KEGG   Symphalangus syndactylus (siamang): 129485911
Entry
129485911         CDS       T10134                                 
Symbol
SQSTM1
Name
(RefSeq) sequestosome-1 isoform X1
  KO
K14381  sequestosome 1
Organism
ssyn  Symphalangus syndactylus (siamang)
Pathway
ssyn04137  Mitophagy - animal
ssyn04140  Autophagy - animal
ssyn04217  Necroptosis
ssyn04218  Cellular senescence
ssyn04380  Osteoclast differentiation
ssyn05014  Amyotrophic lateral sclerosis
ssyn05022  Pathways of neurodegeneration - multiple diseases
ssyn05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssyn00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    129485911 (SQSTM1)
   04137 Mitophagy - animal
    129485911 (SQSTM1)
  09143 Cell growth and death
   04217 Necroptosis
    129485911 (SQSTM1)
   04218 Cellular senescence
    129485911 (SQSTM1)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129485911 (SQSTM1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    129485911 (SQSTM1)
   05022 Pathways of neurodegeneration - multiple diseases
    129485911 (SQSTM1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    129485911 (SQSTM1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ssyn04131]
    129485911 (SQSTM1)
   03029 Mitochondrial biogenesis [BR:ssyn03029]
    129485911 (SQSTM1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ssyn04147]
    129485911 (SQSTM1)
Membrane trafficking [BR:ssyn04131]
 Autophagy
  Mitophagy
   Cargo receptors
    129485911 (SQSTM1)
  Pexophagy
    129485911 (SQSTM1)
  Aggrephagy
    129485911 (SQSTM1)
  Xenophagy
    129485911 (SQSTM1)
  ER-phagy
   ER-phagy recepters
    129485911 (SQSTM1)
  Other autophagy associated proteins
   Midbophagy
    129485911 (SQSTM1)
Mitochondrial biogenesis [BR:ssyn03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    129485911 (SQSTM1)
Exosome [BR:ssyn04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   129485911 (SQSTM1)
SSDB
Motif
Pfam: UBA_5 PB1 ZZ
Other DBs
NCBI-GeneID: 129485911
NCBI-ProteinID: XP_055140928
LinkDB
Position
7:complement(7450466..7482603)
AA seq 439 aa
MASLTVKAYLLGKEDAAREIRRFSFCFSPEPEAEAEAAAGPGPCERLLSRVAALFPALRP
GGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRN
MVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFS
HSRWLRKMKHGHFGWPGWEMGPPGNWSPRPPRAGDARPGPTAESASAPSEDPSVNFLKNV
GESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEKSSSQPSSCCSEPSKPGGNVE
AATQSLAEQMRKIALESEGRPEEQMESDNCSGGDEDWTHLSSKEVDPSTGELQSLQMPES
EGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKN
YDIGAALDTIQYSKHPPPL
NT seq 1320 nt   +upstreamnt  +downstreamnt
atggcgtcgctcaccgtgaaggcctaccttctgggcaaggaggacgcggcgcgcgagatc
cgccgcttcagcttctgcttcagccccgagcctgaggcggaagccgaggctgcggcaggt
cccgggccctgcgagcggctgctgagccgggtggccgccctgttccccgcgctgcggccc
ggcggcttccaggcgcactaccgcgatgaggacggggacttggttgccttttccagtgat
gaggaattgacaatggccatgtcctatgtgaaggatgacatcttccgaatctacattaaa
gagaaaaaagagtgccggcgggaccaccgcccaccgtgtgctcaggaggcgcctcgcaac
atggtgcaccccaatgtgatctgtgatggctgcaatgggcccgtggtaggaacccgctac
aagtgcagcgtctgcccagactacgacttgtgtagcgtctgtgagggaaagggcttgcac
cggggacacaccaagctcgcgttccccagccccttcgggcacctgtctgagggcttctcg
cacagccgctggctccggaagatgaaacacgggcacttcgggtggccaggatgggaaatg
ggtccaccaggaaactggagcccacgtcctcctcgtgcaggagatgcccgccctggtccc
acggcggaatcagcttctgctccatcggaggatcccagcgtgaatttcctgaagaacgtg
ggggagagtgtggcagctgcccttagccctctgggcattgaagttgacattgatgtggag
cacggagggaaaagaagccgcctgacccccgtctctccagagagttccagcacagagaag
agcagctcacagccaagcagctgctgctctgaacccagcaagccgggtgggaacgttgag
gccgccacgcagtctctggcggagcagatgagaaagatcgccttggagtccgaggggcgc
cctgaggaacagatggagtcggataactgttcaggaggagatgaagactggacccacttg
tcttcaaaagaagtggacccgtctacaggtgaactccagtccctacagatgccagaatcc
gaagggccaagctctctggacccctcccaggagggacccacagggctgaaggaagctgcc
ttgtacccgcatctcccgccagaggctgacccacggctgattgagtccctctctcagatg
ctgtccatgggcttctctgatgaaggcggctggctcaccaggctcttgcagaccaagaat
tatgacatcggggcggctctggacaccatccagtattcaaagcatcccccgccattgtga

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