Symphalangus syndactylus (siamang): 129486857
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Entry
129486857 CDS
T10134
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn01522
Endocrine resistance
ssyn04012
ErbB signaling pathway
ssyn04062
Chemokine signaling pathway
ssyn04148
Efferocytosis
ssyn04151
PI3K-Akt signaling pathway
ssyn04360
Axon guidance
ssyn04370
VEGF signaling pathway
ssyn04510
Focal adhesion
ssyn04670
Leukocyte transendothelial migration
ssyn04810
Regulation of actin cytoskeleton
ssyn04935
Growth hormone synthesis, secretion and action
ssyn05100
Bacterial invasion of epithelial cells
ssyn05135
Yersinia infection
ssyn05146
Amoebiasis
ssyn05163
Human cytomegalovirus infection
ssyn05165
Human papillomavirus infection
ssyn05170
Human immunodeficiency virus 1 infection
ssyn05200
Pathways in cancer
ssyn05202
Transcriptional misregulation in cancer
ssyn05205
Proteoglycans in cancer
ssyn05208
Chemical carcinogenesis - reactive oxygen species
ssyn05222
Small cell lung cancer
ssyn05417
Lipid and atherosclerosis
ssyn05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129486857 (PTK2)
04370 VEGF signaling pathway
129486857 (PTK2)
04151 PI3K-Akt signaling pathway
129486857 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
129486857 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129486857 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129486857 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
129486857 (PTK2)
04062 Chemokine signaling pathway
129486857 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
129486857 (PTK2)
09158 Development and regeneration
04360 Axon guidance
129486857 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129486857 (PTK2)
05202 Transcriptional misregulation in cancer
129486857 (PTK2)
05205 Proteoglycans in cancer
129486857 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
129486857 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
129486857 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
129486857 (PTK2)
05163 Human cytomegalovirus infection
129486857 (PTK2)
05165 Human papillomavirus infection
129486857 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
129486857 (PTK2)
05100 Bacterial invasion of epithelial cells
129486857 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
129486857 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129486857 (PTK2)
05418 Fluid shear stress and atherosclerosis
129486857 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
129486857 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssyn01001
]
129486857 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
ssyn01009
]
129486857 (PTK2)
Enzymes [BR:
ssyn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129486857 (PTK2)
Protein kinases [BR:
ssyn01001
]
Non-receptor tyrosine kinases
FAK family
129486857 (PTK2)
Protein phosphatases and associated proteins [BR:
ssyn01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
129486857 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_C_FAK1
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
129486857
NCBI-ProteinID:
XP_055143336
LinkDB
All DBs
Position
7:complement(139593608..139938865)
Genome browser
AA seq
1140 aa
AA seq
DB search
MLLELAGQEALKPAGAIYMEKSGCSPFPVCWAKEYDRYLASSKIMAAAYLDPNLNHTPNS
STKTHLGTGMERSPGTMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL
ANSEKQGMRTHAVSVSGVSHCQHKVKKARRFLPLVFCSHDPPSTDEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMES
RRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITA
MAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTALDLRGIGQVLPTHLMEERLIRQ
QQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKK
PPRPGAPGHLGSLASLSSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLV
KAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNS
DLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
NT seq
3423 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaactggcaggccaagaggccctgaaaccagcaggtgccatctatatggag
aaaagcggctgtagtccatttccagtgtgttgggctaaagaatatgacagatacctagca
tctagcaaaataatggcagctgcttaccttgaccccaacttgaatcacacgccaaattcg
agtactaagactcacctgggtactggtatggaacgttctcctggtacaatggagcgagta
ttaaaggtctttcattattttgaaagcaatagtgagccaaccacctgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcatgtggcctgctatggattccgcctcagtcacctgcggtcagaggaggttcac
tggcttcacgtggatatgggcgtctccagtgtgagggagaagtatgagcttgcccaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagataagccaactttgaatttcttctatcaacaggtgaagagcgattatatg
ttagagatagctgatcaagtggaccaggaaattgctttgaagttgggttgtctagaaata
cggcgatcatactgggagatgcggggcaatgcactagaaaagaagtctaactatgaagta
ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag
gccaaaacactaagaaaactgatccaacaaacatttagacaattcgccaaccttaataga
gaagaaagtattctgaaattctttgagatcctgtctccagtctacagatttgataaggaa
tgcttcaagtgtgctcttggttcaagttggattatttcagtggaactggcaatcggccca
gaagaagggatcagttacctaacggacaagggctgcaatcccacacatcttgctgacttc
actcaagtgcaaaccattcagtattcaaacagtgaagacaaggacagaaaaggaatgcta
caactaaaaatagcaggtgcacccgagcctctgacagtgacggcaccatccctaaccatt
gcggagaatatggctgacctaatagatgggtactgccggctggtgaatggagcctcgcag
tcatttatcatcagaccccagaaagaaggtgaacgggctttgccatcgataccaaagttg
gccaacagcgaaaagcaaggcatgcgaacacacgccgtctctgtgtcaggagtcagtcac
tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccatgat
cctccttctacggatgaaattagtggggacgaaacagatgattatgctgagattatagat
gaagaagatacttacaccatgccctcaaaaagctatggaatagatgaagccagggattat
gagattcaaagagaaagaatagaacttggacgatgtattggagaaggccaatttggagat
gtacatcaaggcgtttatatgagtccagagaatccagctttggcggttgcaattaaaaca
tgtaaaaactgtacttcggacagcgtgagagagaaatttcttcaagaagccttaacaatg
cgtcagtttgaccatcctcatattgtgaagctgattggagtcatcacagagaatcctgtc
tggataatcatggagctgtgcacacttggagagctgaggtcatttttgcaagtaaggaaa
tacagtttggatctagcatctttgatcctgtatgcctatcagcttagtacagctcttgca
tatctagagagcaaaagatttgtacacagggacattgctgctcggaatgttctggtgtcc
tcaaatgattgtgtaaaattaggagactttggattatcccgatatatggaagatagtact
tactacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtcaatcaat
tttcgacgttttacctcagctagtgacgtatggatgtttggtgtgtgtatgtgggagata
ctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtaatcggtcgaatt
gaaaatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagccttatg
acgaaatgttgggcctatgaccccagcaggcggcccaggtttactgaacttaaagctcag
ctcagcacaatcctggaggaagagaaggctcagcaagaagagcgcatgaggatggagtcc
agaagacaggccacagtgtcctgggactccggagggtctgatgaagcgccgcccaagccc
agcagaccgggttatcctagtccgaggtccagtgaaggattttatcccagcccacagcac
atggtacaaaccaatcattaccaggtttctggctaccctggttcacatggaatcacagcc
atggctggcagcatctatccaggtcaggcatctcttttggaccaaacagattcatggaat
catagacctcaggagatagcaatgtggcagcccaatgtggaggactctacagcactggac
ctgcgagggattgggcaagtgttgccaactcatctgatggaagagcggctaatccgacag
caacaggaaatggaagaagatcagcgctggctggaaaaagaggaaagatttctgaaacct
gatgtgagactctctcgaggcagtattgacagggaggatggaagtcttcagggtccgatt
ggaaaccaacatatatatcagcctgtgggtaaaccagatcctgcagctccaccaaagaaa
ccgcctcgccctggagctcccggtcatctgggaagccttgccagcctcagcagccctgct
gacagctacaacgagggtgtcaagccatggaggcttcagccccaggaaatcagcccccct
cctactgccaacctggaccggtcgaatgataaggtgtatgagaatgtgacaggcctggtg
aaagctgtcatcgagatgtccagtaaaatccagccagccccaccagaggagtacgtccct
atggtgaaggaagtcggcttggccctgaggacgttattggccactgtggatgagaccatt
cccctcctaccagccagcacccaccgagagattgagatggcacagaaactattgaactct
gacctgggagagctcatcaacaagatgaaactggcccagcagtatgtcatgaccagcctc
cagcaagagtacaaaaagcaaatgctgactgctgctcacgccctggctgtggatgctaaa
aacttactcgatgtcattgaccaagcaagactgaaaatgcttgggcagacgagaccacac
tga
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