KEGG   Symphalangus syndactylus (siamang): 129486883
Entry
129486883         CDS       T10134                                 
Name
(RefSeq) cytochrome P450 11B1, mitochondrial isoform X1
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
ssyn  Symphalangus syndactylus (siamang)
Pathway
ssyn00140  Steroid hormone biosynthesis
ssyn01100  Metabolic pathways
ssyn04927  Cortisol synthesis and secretion
ssyn04934  Cushing syndrome
Module
ssyn_M00108  C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
ssyn_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ssyn00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    129486883
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    129486883
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    129486883
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ssyn00199]
    129486883
Enzymes [BR:ssyn01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     129486883
Cytochrome P450 [BR:ssyn00199]
 Cytochrome P450, animal type
  CYP11 family
   129486883
SSDB
Motif
Pfam: p450 INT1_R3
Other DBs
NCBI-GeneID: 129486883
NCBI-ProteinID: XP_055143437
LinkDB
Position
7:complement(141749270..141756757)
AA seq 503 aa
MALRAKAEVCVAVPWLSLQRAQALGTRAARASRTVLPFEAMPQRPGNRWLRLLQIWREQG
YEHLHLEMHQTFQELGPIFRFDLGGARMVCVMLPEDVEKLQQVDSLHPRRMSLEPWVAYR
QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALRKKVLQNA
RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM
PRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQQYNSIVAELLLNAELS
PDAIKANSMELTAGSVDTTVFPLLMTLFELARNPDVQQALRQESLAAAASISEHPQKATT
ELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNTALFPRP
ERYNPQRWLDIRGSGRNFYHLPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETVTQED
IKMVYSFILRPSTFPLLTFRAIN
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggcactcagggcaaaggcagaggtgtgcgtggcagtgccctggctgtccctgcaaagg
gcacaggcactgggcactagagccgctcgggcctctaggacggtgctgccctttgaagcc
atgccccagcgtccaggcaacaggtggctgaggctgctgcagatctggagggagcagggt
tacgagcacctgcacctggagatgcaccagaccttccaggaactggggcccattttcagg
ttcgacttgggaggagcacgcatggtgtgtgtgatgctgccggaggacgtggagaagctg
cagcaggtggacagcctgcatccccgcaggatgagcctggagccctgggtggcctacaga
caacatcgtgggcacaaatgtggcgtgttcttgctgaatgggcctgaatggcgcttcaac
cgattgcggctgaacccagatgtgctgtcgcccaaggccgtgcagaggttcctcccgatg
gtggatgcggtggccagggacttctcccaggccctcaggaagaaggtgctgcagaacgcc
cgggggagcctgaccctggacgtccagcccagcatcttccactacaccatagaagccagc
aacttagctctttttggagagcggctgggcctggttggccacagccccagctctgccagc
ctgaacttcctccatgccctggaggtcatgttcaaatccactgtccagctcatgttcatg
cccaggagcctgtctcgctggaccagccccaaggtgtggaaggagcactttgaggcctgg
gactgcatcttccagtacggcgacaactgtatccagaaaatctatcaggaactggccttc
aaccgccctcaacagtacaacagcattgtggcggagctcctgttgaatgcggaactgtcg
ccagatgccatcaaggccaactctatggaactcactgcagggagcgtggacacgacggtg
tttcccttgctgatgacgctctttgagctggctcggaaccccgacgtgcagcaggccctg
cgtcaggagagcctggccgccgcagccagcatcagtgaacatccccagaaggcaaccacc
gagctgcccttgctgcgggcggccctcaaggagaccttgaggctctaccctgtgggtctg
tttttggagcgagtggcgagctcagacttggtgcttcagaactaccacatcccagctggg
acattggtgcgcgtgttcctctactctctgggtcgcaacaccgccttgttcccgaggccg
gagcgctataacccccagcgctggctagacatcaggggctccggcaggaacttctaccac
ttgccctttggctttggcatgcgccagtgcctcgggcggcgcctggcagaggcagagatg
ctgctgctgctgcaccatgtgctgaaacacctccaggtggagacagtaacccaagaggat
ataaagatggtctacagcttcatattgaggcccagcacgttccccctcctcaccttcaga
gccatcaactaa

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