Symphalangus syndactylus (siamang): 129488275 Help Entry 129488275         CDS       T10134                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X3   KO K04398   caspase 8 [EC:3.4.22.61] Organism ssyn  Symphalangus syndactylus (siamang) Pathway ssyn01524   Platinum drug resistance ssyn04115   p53 signaling pathway ssyn04210   Apoptosis ssyn04215   Apoptosis - multiple species ssyn04217   Necroptosis ssyn04620   Toll-like receptor signaling pathway ssyn04621   NOD-like receptor signaling pathway ssyn04622   RIG-I-like receptor signaling pathway ssyn04623   Cytosolic DNA-sensing pathway ssyn04625   C-type lectin receptor signaling pathway ssyn04657   IL-17 signaling pathway ssyn04668   TNF signaling pathway ssyn04932   Non-alcoholic fatty liver disease ssyn04936   Alcoholic liver disease ssyn05010   Alzheimer disease ssyn05016   Huntington disease ssyn05022   Pathways of neurodegeneration - multiple diseases ssyn05132   Salmonella infection ssyn05134   Legionellosis ssyn05142   Chagas disease ssyn05145   Toxoplasmosis ssyn05152   Tuberculosis ssyn05160   Hepatitis C ssyn05161   Hepatitis B ssyn05162   Measles ssyn05163   Human cytomegalovirus infection ssyn05164   Influenza A ssyn05165   Human papillomavirus infection ssyn05167   Kaposi sarcoma-associated herpesvirus infection ssyn05168   Herpes simplex virus 1 infection ssyn05169   Epstein-Barr virus infection ssyn05170   Human immunodeficiency virus 1 infection ssyn05200   Pathways in cancer ssyn05203   Viral carcinogenesis ssyn05416   Viral myocarditis ssyn05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ssyn00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     129488275 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     129488275 (CASP8)    04215 Apoptosis - multiple species     129488275 (CASP8)    04217 Necroptosis     129488275 (CASP8)    04115 p53 signaling pathway     129488275 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     129488275 (CASP8)    04621 NOD-like receptor signaling pathway     129488275 (CASP8)    04622 RIG-I-like receptor signaling pathway     129488275 (CASP8)    04623 Cytosolic DNA-sensing pathway     129488275 (CASP8)    04625 C-type lectin receptor signaling pathway     129488275 (CASP8)    04657 IL-17 signaling pathway     129488275 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129488275 (CASP8)    05203 Viral carcinogenesis     129488275 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     129488275 (CASP8)    05161 Hepatitis B     129488275 (CASP8)    05160 Hepatitis C     129488275 (CASP8)    05164 Influenza A     129488275 (CASP8)    05162 Measles     129488275 (CASP8)    05168 Herpes simplex virus 1 infection     129488275 (CASP8)    05163 Human cytomegalovirus infection     129488275 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     129488275 (CASP8)    05169 Epstein-Barr virus infection     129488275 (CASP8)    05165 Human papillomavirus infection     129488275 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     129488275 (CASP8)    05134 Legionellosis     129488275 (CASP8)    05152 Tuberculosis     129488275 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     129488275 (CASP8)    05142 Chagas disease     129488275 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     129488275 (CASP8)    05016 Huntington disease     129488275 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     129488275 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     129488275 (CASP8)    05416 Viral myocarditis     129488275 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     129488275 (CASP8)    04932 Non-alcoholic fatty liver disease     129488275 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     129488275 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ssyn01002]     129488275 (CASP8) Enzymes [BR:ssyn01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      129488275 (CASP8) Peptidases and inhibitors [BR:ssyn01002]  Cysteine peptidases   Family C14: caspase family    129488275 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  129488275 NCBI-ProteinID:  XP_055146188 LinkDB All DBs Position 8:105532303..105589309 Genome browser AA seq 496 aa AA seqDB search MVPGKGGADYILLPFEKMDFSRNLYDIGEQLGSEDLASLKFLSLDYIPQRKQEPIKDALM LFQRLQEKRMLEESNLSFLKELLFRINRLDLLIAYLNTRKEEMERELQTPGRAQISAYRV MLYQISEEVSRSELKSFKFLLQKEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRV CAQINKSLLKIINNYEEFSRERRSSLEGNPDEFSNVEELCGVMTISDSPREQDSESQTLD KVYQMKSKPRGYCLIINNYDFTKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKP HNDCTVQQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGKEAPIYELTSQFTGL KCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQARYIPDEADFLLGM ATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQM PQPTFTLRKKLVFPSD NT seq 1491 nt NT seq  +upstreamnt  +downstreamnt atggtgccaggaaagggtggagcggattatattctcctgccttttgaaaagatggacttc agcagaaatctttatgatattggggaacaactgggcagtgaagatctggcctccctcaag ttcctgagcctggactacattccacaaaggaagcaagaacccatcaaggatgccttgatg ttattccagagactccaggaaaagagaatgttggaggaaagcaatctgtccttcctgaag gagctgctcttccgaattaatagactggatttgctgattgcctacctaaacactagaaag gaggagatggaaagggaacttcagacaccaggcagggctcagatttctgcctacagggtc atgctgtatcagatttcagaagaagtgagcagatcagaattgaagtcttttaagtttctt ttgcaaaaggaaatctccaaatgcaaactggatgatgacatgaacctgctggatattttc atagagatggagaagagggtcatcctgggagaaggaaagttggacatcctgaaaagagtc tgtgcccaaatcaacaagagcctgctgaagataatcaacaactatgaagaattcagcaga gagagaagaagcagccttgaaggaaatcctgatgaattttcaaatgtggaggagttgtgt ggggtaatgacaatctcggactctccaagagaacaggatagtgaatcacagactttggac aaagtttaccaaatgaaaagcaaacctcgaggatactgtctgatcatcaacaattatgat tttacaaaagcacgggagaaagtgcccaaacttcacagcattagggacaggaatggaaca cacttggatgcaggggctttgaccacgacctttgaagagcttcattttgagatcaagccc cacaatgactgcacagtacagcaaatctatgagattttgaaaatctaccaactcatggac cacagtaacatggactgcttcatctgctgtatcctctcccatggagacaagggcatcatc tacggcactgatggcaaggaggcccccatctatgagctgacatctcagttcactggtttg aagtgcccttcccttgctggaaaacccaaagtgttttttattcaggcttgtcagggggat aactaccagaaaggtatacctgttgagactgattcagaggagcaaccctatttagaaatg gatttatcatcacctcaagcgagatatatcccggatgaggctgactttctgctggggatg gccactgtgaataactgtgtttcctaccgaaatcctgcagagggaacctggtacatccag tcactttgccagagcctgagagagcgatgtcctcgaggcgatgatattctcaccatcctg actgaagtgaactatgaagtaagcaacaaggatgacaagaaaaacatggggaaacagatg ccgcagcctactttcacactaagaaaaaaacttgtcttcccttctgattga

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