Streptomyces tanashiensis: LDH80_13735
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Entry
LDH80_13735 CDS
T08718
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
staa
Streptomyces tanashiensis
Pathway
staa00020
Citrate cycle (TCA cycle)
staa00630
Glyoxylate and dicarboxylate metabolism
staa00785
Lipoic acid metabolism
staa01100
Metabolic pathways
staa01110
Biosynthesis of secondary metabolites
staa01120
Microbial metabolism in diverse environments
staa01200
Carbon metabolism
staa01210
2-Oxocarboxylic acid metabolism
Module
staa_M00009
Citrate cycle (TCA cycle, Krebs cycle)
staa_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
staa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
LDH80_13735
00630 Glyoxylate and dicarboxylate metabolism
LDH80_13735
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LDH80_13735
Enzymes [BR:
staa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
LDH80_13735
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
LDH80_13735
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
LDH80_13735
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
LDH80_13735
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UZX21716
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Position
3118912..3122697
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AA seq
1261 aa
AA seq
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MSSQSPSTPSSPAHQDGQGVSPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GASETPAAPAATTQSAPAAAQAGPAQAAPAVPAPAPAPVAAPAPAPAPVKPAAAPAPVAA
KPAAAAPAAAKAAPAKEAPAGPELITLRGPAAAVAKNMNASLEVPTATSVRAVPVKLLFD
NRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKDGKPTLVKPEHVNFGL
AIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVKRARVGKLTMEDFSGVTVSLTNP
GGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQ
GAASGEFLRVVANFLLGEEGFYDEIFKALRIPYEPVRWLKDIDASHDDDVTKAARVFELI
HSYRVRGHVMADTDPLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMKLRDILG
VLRDSYCRTTGVEFMHIQDPKQRKWIQDRVERPHSRVEREEQLRILRRLNAAEAFETFLQ
TKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQI
FREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEAVDPVLEGIVR
AKQDVINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGF
TAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQTFNKDVVIDLICY
RRRGHNEGDNPQFTNPQMYNLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEK
VFAEVREATAAPAATTVPDAQAEFPVGVTTAVSQEVVKRIAESQVSIPERITVHPRLLPQ
MQRRAASIDDGTIDWGFGETLAIGSLLMEGTPVRLSGQDSRRGTFGQRHAVLVDQETGED
YTPLLYLTEDQAHYNVYDSLLSEYAAMGFEYGYSLARPDSLVIWEAQFGDFVNGAQTVVD
EFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNMTVAMPTLPSNYF
HLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKVEEFTTGGFRPVIGDSTANPADVRKVVF
CAGKVYYDLEAERQKRGDTETAIIRLERLYPLPGAELQAEIAKYPNAAKYIWAQEEPANQ
GAWPFIALNLIDHLDLAVGADIPAGERLRRISRPHSSSPAVGSAKRHQAEQQQLVNEVFD
A
NT seq
3786 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaccccgagctccccggcccaccaagacgggcagggcgtg
agccccgcagccgccttcggtgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaattcggtcgatcgtgcctggtgggacttcttcgccgactacaagccc
ggagcgtcggagaccccggccgccccggccgccaccactcagagcgcgcccgccgcggcg
caggcgggccccgcacaggccgcgcctgccgttccggcccccgcgcccgccccggtcgcg
gccccggccccggccccggctccggtgaagcccgccgcggcccccgcgccggtcgccgcg
aagcccgccgccgccgctccggccgcggcgaaggccgcgccggcgaaggaggcccccgcc
ggccccgagctgatcacgctgcgcggccccgccgccgcggtcgcgaagaacatgaacgcc
tccctggaggtgccgacggccacgtccgtccgcgccgtcccggtgaagctgctcttcgac
aaccggatcgtgatcaacaaccacctgaagcgcgcccggggcgggaagatctccttcacg
cacctcatcggctacgcgatggtgcaggcgatcaaggccatgccgtcgatgaactactcc
ttcgcggagaaggacggcaagccgaccctggtcaagccggagcacgtgaacttcggtctc
gcgatcgacctggtcaagcccaacggcgaccgccagctcgtcgtcgcgggcatcaagaag
gccgagacgctcaacttcttcgagttctggcaggcctacgaggacatcgtcaagcgcgcc
cgcgtgggcaagctgacgatggaggacttctccggcgtcacggtctccctgaccaacccc
ggcggcctcggcaccgtccactccgtgccgcgtctgatgcccggacagtcggtcatcatg
ggcgtcggctcgatggactacccggcggagttccagggcacttcccaggacaccctgaac
aagctgggcatctccaaggtcatgaccctgacctcgacgtacgaccaccgcgtcatccag
ggcgccgcctccggcgagttcctgcgcgtcgtcgccaacttcctcctcggcgaggagggc
ttctacgacgagatcttcaaggccctgcgcatcccctacgagccggtccgctggctcaag
gacatcgacgcctcgcacgacgacgacgtcaccaaggccgcgcgcgtcttcgagctgatc
cactcctaccgggtccgcggccacgtcatggccgacaccgacccgctggagtacaagcag
cgcaagcaccccgacctggacatcaccgagcacggcctcaccctgtgggacctggagcgc
gagttcgcggtcggcggcttcgccggcaagtcgatgatgaagctccgcgacatcctcggc
gtgctccgcgactcgtactgccgcaccaccggcgtcgagttcatgcacatccaggacccg
aagcagcgcaagtggatccaggaccgcgtcgagcgcccgcactcccgcgtggagcgcgag
gagcagctgcggatcctgcgccggctgaacgcggcggaggccttcgagaccttcctgcag
acgaagtacgtcggccagaagcgcttctccctggagggcggcgagtccgtcatcccgctg
ctcgacgcggtcatcgactcggccgccgagtcgcgcctcgacgaggtcgtcatcggcatg
gcccaccgcggccggctgaacgtcctggcgaacatcgtcggcaagtcgtacgcgcagatc
ttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtgaag
taccacctgggcgccgagggcaccttcacgggcctcgacggcgagcagatcaaggtctcc
ctggccgccaacccctcgcacctggaggcggtcgacccggtcctggaaggcatcgtccgc
gccaagcaggacgtcatcaacaagggcggcacggacttcaccgtcctgcccgtcgccctc
cacggcgacgcggccttcgccggccagggtgtcgtcgccgagacgctgaacatgtcgcag
ctgcggggctaccgcaccggcggcacggtccacatcgtcatcaacaaccaggtcggcttc
accgccgccccggagtcctcgcgttcctcgatgtacgcgaccgacgtggcccgcatgatc
gaggcgccgatcttccacgtgaacggcgacgacccggaggccgtcgtccgcgtcgcgcgg
ctcgccttcgagttccgccagacgttcaacaaggacgtcgtgatcgacctcatctgctac
cgccgccgcggtcacaacgagggcgacaacccgcagttcaccaacccgcagatgtacaac
ctgatcgacaagaagcgttcggtgcgcaagctgtacaccgagtcgctcatcggtcgcggc
gacatcaccctcgaagaggcggagcaggcgctccaggacttccagggccagctggagaag
gtgttcgcggaggtccgcgaggccaccgccgccccggcggcgacgaccgtcccggacgcg
caggccgagttcccggtcggcgtgaccaccgcggtctcccaggaggtcgtgaagcggatc
gccgagtcgcaggtcagcatcccggagcggatcacggtccacccgcgtctgctcccgcag
atgcagcgccgtgccgcctcgatcgacgacggcaccatcgactggggcttcggcgagacc
ctcgccatcggctccctgctgatggagggcaccccggtccgcctctcgggccaggactcc
cgccgcggcaccttcggccagcgccacgcggtcctggtcgaccaggagaccggcgaggac
tacaccccgctgctctacctgaccgaggaccaggcccactacaacgtctacgactcgctg
ctcagcgagtacgcggcgatgggcttcgagtacggctactcgctggcccgcccggactcc
ctggtcatctgggaggcccagttcggtgacttcgtcaacggcgcgcagaccgtcgtcgac
gagttcatctcctcggccgagcagaagtggggccagacctccggcgtcacgctgctcctg
ccgcacggctacgagggccagggcccggaccactcgtccgcgcgcccggagcgcttcctc
cagatgtgcgcccaggacaacatgacggtcgccatgccgacgctgccgtcgaactacttc
cacctcctgcgctggcaggtgcacaacccgcaccacaagccgctcatcgtcttcaccccg
aagtcgatgctgcgtctgaaggccgcggcgtccaaggtggaggagttcaccaccggcggc
ttccgcccggtgatcggcgactcgacggccaacccggccgatgtccgcaaggtcgtcttc
tgcgccggcaaggtctactacgacctggaggccgagcgtcagaagcgcggtgacacggag
accgcgatcatccgtctggagcgtctgtacccgctgccgggtgccgagctgcaggccgag
atcgccaagtacccgaacgccgcgaagtacatctgggcgcaggaggagccggcgaaccag
ggtgcctggccgttcatcgcgctcaacctgatcgaccacctggacctggcggtcggcgcg
gacatcccggcgggcgagcgcctgcgccggatctcgcgtccgcactcctcctccccggcg
gtcggctcggccaagcgccaccaggcggagcagcagcagctggtcaacgaggtcttcgac
gcctga
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