KEGG   Streptomyces sp. CMC78: SCMC78_30520
Entry
SCMC78_30520      CDS       T11197                                 
Name
(GenBank) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
stcm  Streptomyces sp. CMC78
Pathway
stcm00253  Tetracycline biosynthesis
stcm01056  Biosynthesis of type II polyketide backbone
stcm01100  Metabolic pathways
stcm01110  Biosynthesis of secondary metabolites
Module
stcm_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:stcm00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    SCMC78_30520
   00253 Tetracycline biosynthesis
    SCMC78_30520
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:stcm01004]
    SCMC78_30520
   01008 Polyketide biosynthesis proteins [BR:stcm01008]
    SCMC78_30520
Enzymes [BR:stcm01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     SCMC78_30520
    2.3.1.260  tetracycline polyketide synthase
     SCMC78_30520
Lipid biosynthesis proteins [BR:stcm01004]
 Polyketide synthase
  Component type
   SCMC78_30520
Polyketide biosynthesis proteins [BR:stcm01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     SCMC78_30520
    Nonaketide PKS
     SCMC78_30520
    Decaketide PKS
     SCMC78_30520
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_N Calici_MSP
Other DBs
NCBI-ProteinID: BFP53245
UniProt: A0AB33KNL8
LinkDB
Position
complement(3356723..3357991)
AA seq 422 aa
MERRAVITGIGVCAPGGTGVDSFWELMCDGRTATRGITLFDPSPYRSRVAAEIDFDPRAH
GLTPQEIRRMDRAAQFGVVTAREAFADSGLAGAALDPFRTGVSLGTAIGAAGGLDAEYRV
VSDDGRLELVDHRYATPHLYDLFVPSSFATEVAWAVGAEGPATVVSTGCTAGIDAVGHAV
EAIRDGSADVMVTGAVDAPITPLTMAAFDAIRATTSLNDEADTASRPFDASRKGFVLGEG
AAVFVLEEAEHARRRGAYVYAEIAGYASRGNAFHMTGLRSDGAELAAAIRAALDEARLDA
SAVDYVNAHGSGTRQNDRHETVALKSALGQHAHRVPVSAIKSMVGHSLGAIGSIEIAACA
LAMRHHVIPPTANLHTPDPECDLDYVPLTARAQRTDAVLTIGSGFGGFQSAMVLARPDRS
AA
NT seq 1269 nt   +upstreamnt  +downstreamnt
gtggaacgccgggcagtgatcacgggaatcggtgtgtgcgcaccgggcggaaccggtgtg
gacagcttctgggagctgatgtgcgacggccggacggccacccgcggcatcaccctcttc
gacccgtctccgtaccgctccagggtcgccgccgagatcgacttcgacccgcgggcgcac
ggactgacgccgcaggagatccggcggatggaccgggccgcgcagttcggcgtggtgacg
gcacgggaggccttcgccgacagcgggctcgccggcgccgcgctcgatccgttccgtacg
ggagtcagcctcggcaccgcgatcggcgcggccggcggcctggacgcggagtaccgcgtg
gtcagcgacgacggccggctggagctggtcgaccaccggtacgcgacaccgcatctgtac
gacctgttcgtgccgagctccttcgcgaccgaagtggcctgggccgtcggcgcggaagga
ccggcgacggtggtgtccaccggctgcaccgccgggatcgacgcggtgggccacgcggtg
gaggcgatccgcgacggcagcgccgatgtgatggtcaccggcgcggtggacgcgccgatc
accccgctcacgatggcggccttcgacgcgatccgcgccaccacgtccctcaacgacgag
gcggacaccgcctcccgccccttcgacgcgtcacgcaagggcttcgtcctcggtgagggg
gcggcggtgttcgtcctggaggaggcggagcacgcacggcgcagaggcgcgtacgtgtac
gcggagatcgccggatacgcctcgcgcggcaacgccttccacatgaccggactgcggtcc
gacggagcggagctggccgccgcgatccgggcggcgctggacgaggcccggctcgacgcg
tcggcggtggactacgtcaacgcgcacggctccggcacccgccagaacgaccggcacgag
acggtcgcgctcaagtcggctctgggacagcacgcccaccgggtgccggtcagcgcgatc
aagtcgatggtcgggcactcgctcggggcgatcggctccatcgagatcgccgcctgcgca
ctggccatgcggcaccacgtcatccctccgaccgccaatctgcacaccccggatcccgag
tgcgatctcgactatgtcccgctgacggcccgcgcgcagcgcaccgatgccgtcctcacc
atcggcagcggattcggcggcttccagagcgcgatggtgctggcccgtcccgacaggagc
gccgcgtga

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