Streptomyces sp. CA-256286: JHY03_18790
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Entry
JHY03_18790 CDS
T11337
Symbol
aceE_2
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stcz Streptomyces sp. CA-256286
Pathway
stcz00010
Glycolysis / Gluconeogenesis
stcz00020
Citrate cycle (TCA cycle)
stcz00620
Pyruvate metabolism
stcz00785
Lipoic acid metabolism
stcz01100
Metabolic pathways
stcz01110
Biosynthesis of secondary metabolites
stcz01120
Microbial metabolism in diverse environments
stcz01200
Carbon metabolism
stcz01210
2-Oxocarboxylic acid metabolism
Module
stcz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stcz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
JHY03_18790 (aceE_2)
00020 Citrate cycle (TCA cycle)
JHY03_18790 (aceE_2)
00620 Pyruvate metabolism
JHY03_18790 (aceE_2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
JHY03_18790 (aceE_2)
Enzymes [BR:
stcz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
JHY03_18790 (aceE_2)
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QTA31743
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All DBs
Position
2122889..2125621
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AA seq
910 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGDEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDQGDGGDQIFFQGHASPGIYARAFLLDRLSEAQLDAFRQ
EKSKAPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRTGILVNKLNTTPDGQFQTYATETGSYIREHFFGDDPRLR
DMVKDMTDQQILHLGRGGHDHKKVYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVEDLKRFRDRLHIPITDKQLDEGYPPYYHPGRDSEEIQYMHDRRNGLGGYVP
TRVVRAKPLPQPVEKTYAAAKKGSGQQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGYEIAHIMQDGLRRMYGEANEDVFYYLTVYNEPIQHPAEPE
NVDVDGILKGVYRFKQGEAGEIPAQILASGVAVPWAVEAQRILAEEWNVKADVWSATSWN
ELRREAVDVERYNLLHPEEEQRVPYVTRKLEGAGGPFVAVSDWMRSVPDQIARWVPGAYQ
SLGADGFGFADTRGAARRFFHIDAQSIVLAVLTELAKEGKIDRSSLKTALDRYDLLDVAA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttccgagccaggtcccg
gattttgatcccgaagagacccaggaatggctcgactccctcgacgccgccgtcgacgag
cgaggccgtgagcgggcccgctacctcatgctccggctcatcgagcgcgcgcgggagaag
cgcgtcgccgtgccggagatgcgcagcacggactacgtgaacacgatcgccacgaaggac
gagccgttcttccccggcgacgaggagatcgagcgcaaggtcctcaacgcgacccgctgg
aacgcggccgtgatggtctcccgggcgcagcgtcccggaatcggcgtcggcggccacatc
gccaccttcgcctcctccgcctcgctgtacgacgtgggcttcaaccacttcttccgcggc
aaggaccagggcgacggcggcgaccagatcttcttccaggggcacgcgtccccggggatc
tatgcccgcgcgttcctgctcgaccggctgagcgaggcgcagctcgacgcgttccggcag
gagaagtcgaaggccccgaacgggctttccagctacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtctcgatgggtctcggcccgctcggtgcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggtatcgccgacacgtccaagtcgcacgtctgg
gcctatctgggcgacggcgagatggacgagcccgagtcgcttggccagctctccatcgcc
gcgcgtgagggcctggacaacctgaccttcgtcgtcaactgcaacctgcaacgcctcgac
gggcctgtgcgcggcaacggcaagatcatccaggagctggagtcacagttccggggcgcc
ggctggaacgtcatcaagctggtctgggaccggtcctgggacccgctgctggcgcaggac
cgcacgggcatcctggtcaacaagctgaacaccacgccggacgggcagttccagacgtac
gccaccgagaccggctcgtacatccgcgagcacttcttcggtgacgacccgcggctgcgc
gacatggtcaaggacatgaccgaccagcagatcctgcacctggggcgcggcgggcacgac
cacaagaaggtctacgcggcctacgcggcggccaaggcgcacaagggccagccgaccgtg
atcctcgcgcagacggtcaagggctggacgctggggccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctcacggtcgaggacctcaagcggttccgcgaccggctgcac
atcccgatcaccgacaagcagctggacgagggctacccgccctactaccacccgggccgc
gactcggaggagatccagtacatgcacgaccgccgcaacggtctgggcggctatgtgccg
acccgggtggtgcgtgcgaagcccctgccgcagcccgtggagaagacgtacgcggctgcg
aagaaggggtcgggtcagcagtcgatcgccaccaccatggcgttcgtccgcatcctcaag
gacctcatgcgggacaaggagatcggcaagcggttcgtgctgatcgcacccgatgagtac
cgcacgttcgggatggacgcgttcttcccgagcgcgaagatctacaacccgctgggccag
cagtacgaggcggtcgaccgcgatctgctgctcgcgtacaaggagtcgccgacgggtcag
atgctgcacgacggcatctccgaggcgggctgtacggcctcgctgatcgccgccggttcg
gcgtacgcgacgcacggcgagccgctgatcccggtttacgtcttctactcgatgttcggg
ttccagcgcaccggtgaccagttctggcagatggccgaccagctcgcgcgcggtttcgtg
ctgggtgcgaccgccgggcgtacgacgctgaccggtgagggcctccagcacgcggacggc
cactcgcagctgctcgcctcgaccaacccgggctgcgtcgcctacgacccggccttcggg
tacgagatcgcgcacatcatgcaggacgggctgcgccggatgtacggcgaggcgaacgag
gacgtcttctactacctcaccgtctacaacgagccgatccagcacccggccgagcccgag
aacgtcgacgtggacggcatcctcaagggtgtctaccgcttcaagcagggcgaggcgggc
gagatcccggcgcagatcctggcgtccggtgtggcggtcccgtgggccgtcgaggcgcag
cggatcctcgccgaggagtggaacgtcaaggcggacgtctggtcggcgacctcctggaac
gagctgcggcgcgaggccgtggacgtggagcggtacaacctcctccacccggaggaggag
cagcgcgtcccgtacgtgacgcggaagctggaaggggccgggggcccgttcgtggcggtc
tcggactggatgcgttcggtgccggaccagatcgcgcgctgggtgcccggtgcgtaccag
tcgctgggtgcggacggcttcggcttcgccgacacccgtggtgcggcccgccggttcttc
cacatcgacgctcagtcgatcgtcctcgcggtgctcaccgagctcgcgaaggaggggaag
atcgaccggtcctccctgaagacggcgctggaccgttacgacctcctggatgtggccgcg
gccgatccgggcgcggcgggcggcgacgcgtaa
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