Streptomyces sp. FR-008: SFR_2010
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Entry
SFR_2010 CDS
T11627
Name
(GenBank) Alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
stfr Streptomyces sp. FR-008
Pathway
stfr00020
Citrate cycle (TCA cycle)
stfr00630
Glyoxylate and dicarboxylate metabolism
stfr00785
Lipoic acid metabolism
stfr01100
Metabolic pathways
stfr01110
Biosynthesis of secondary metabolites
stfr01120
Microbial metabolism in diverse environments
stfr01200
Carbon metabolism
stfr01210
2-Oxocarboxylic acid metabolism
Module
stfr_M00009
Citrate cycle (TCA cycle, Krebs cycle)
stfr_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
stfr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SFR_2010
00630 Glyoxylate and dicarboxylate metabolism
SFR_2010
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SFR_2010
Enzymes [BR:
stfr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SFR_2010
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SFR_2010
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SFR_2010
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SFR_2010
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Trypco1
Motif
Other DBs
NCBI-ProteinID:
ALM38625
LinkDB
All DBs
Position
2089729..2093625
Genome browser
AA seq
1298 aa
AA seq
DB search
MWCDFHDGCPARPAPLGDEGVAFIPAVHHLVKRKRAVAAVSPQSPSNSSVSTDQAGQGKS
PAAAFGSNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPGGGGTAPVETAAPSAATPVAP
AKPAPAAKAPEAKPAAAPAKPAEQAPAAKAAPAKTAPAKAAPAKPAAKAAEPAAPAEGPE
FVTLRGPSAAVAKNMSASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLI
GYAMVQAIKAMPSMNNSFAQKDGKPTLVKPEHINLGLAIDLVKPNGDRQLVVAAIKKAET
LNFFEFWQAYEDIVRRARDNKLTMDDFSGVTVSLTNPGGIGTVHSVPRLMPGQSVILGVG
AMEYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRIVANLLLGENEFYD
DIFKALRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYHQRKH
PDLDINEHGLTLWDLERTFAVGGFAGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQR
KWIQDRVERGPGKPEREEQLRILRRLNSAEAFETFLQTKYVGQKRFSLEGGESVIPLLDA
VLDSAAEARLDEVVVGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHL
GAEGTFTGLDGEQIKVSLTANPSHLEAVDPVMEGVVRAKQDIINKGGTDFTVLPVALHGD
AAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAP
IFHVNGDDPEAVVRVGRLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLID
KKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVREATSHPVEHEPEGPEAE
FPVTVNTAVSPEVVKRIAESQVNIPERVTVHPRLLPQLQRRAAMVEDGTIDWGMGETLAI
GSLLMEGTPVRLSGQDSRRGTFGQRHAVLIDRETGDDYTPLLYLSDNQARYNIYDSLLSE
YAAMGFEYGYSLARPESLVLWEAQFGDFVNGAQTVVDEFISSAEQKWSQHSGVTLLLPHG
YEGQGPDHSSARPERFLQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSM
LRLKAAASKAEEFTTGGFRPVIGDDSVDASQVRKVVLCAGKVYYDLEAERQKRGVTDTAI
IRVERLYPLPGAELQAEIAKYPNAEKFLWAQEEPANQGFWPFIALNLIDHLDLGVGADLP
AAERLRRISRPHSSSPAVGSAKRHQAEQAQLVAEVFDA
NT seq
3897 nt
NT seq
+upstream
nt +downstream
nt
atctggtgtgactttcacgacggatgcccggcccggcctgcacctctcggtgacgaaggc
gtagcctttattcccgctgtccaccaccttgtgaagcggaagagggcggttgccgccgtg
tcgccacagtcccccagtaattcgagcgtctcgaccgaccaagcggggcagggcaagagt
cctgccgccgcgttcgggtcgaacgagtggctcgtcgacgagatctaccagcagtacctc
caggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagcccggc
gggggtggcacggctcccgtggagaccgcggccccctcggccgcgaccccggtcgcgccg
gccaagcccgctccggcggccaaggcccccgaggcgaagccggctgccgcgccggccaag
cccgccgagcaggcgccggccgccaaggccgcccccgcgaagacggcccccgccaaggcc
gctccggccaagcccgccgcgaaggccgccgagcctgccgcgcccgcggaaggcccggag
ttcgtcacgctgcgtggcccctcggccgcggtcgcgaagaacatgagcgcctcgctggag
ctgcccacggccacgtccgtgcgcgcggtgccggtcaagctcctcttcgacaaccgcatc
gtcatcaacaaccacctgaagcgcgcccggggcgggaagatctccttcacgcacctgatc
ggctacgccatggtgcaggccatcaaggccatgccgtcgatgaacaactccttcgcgcag
aaggacggcaagccgacgctggtcaagcccgagcacatcaacctcgggctcgccatcgac
ctggtcaagcccaacggcgaccgccagctcgtcgtcgcggccatcaagaaggccgagacc
ctcaacttcttcgagttctggcaggcgtacgaggacatcgtccgccgggcccgggacaac
aagctgacgatggacgacttctcgggcgtcaccgtctcgctgaccaaccccggcggcatc
ggcaccgtccactcggtgccgcgtctgatgcccggccagtcggtgatcctcggcgtgggc
gcgatggagtacccggcggagttccagggcacctcgcaggacaccctgaacaagctcggc
atctcgaaggtcatgaccctgacgtcgacctacgaccaccgggtcatccagggcgccgcc
tccggcgagttcctgcggatcgtcgccaacctgctgctcggcgagaacgagttctacgac
gacatcttcaaggcgctgcgcatcccctacgagccggtccgctggctcaaggacatcgac
gcctctcacgacgacgacgtcaccaaggccgcccgcgtcttcgagctgatccactcctac
cgggtccgcggccacgtcatggccgacaccgacccgctcgagtaccaccagcgcaagcac
cccgacctcgacatcaacgagcacgggctcacgctgtgggacctggagcgcaccttcgcc
gtcggcggcttcgccggcaagtcgatgatgaagctccgcgacatcctcggcgtcctgcgc
gactcgtactgccgcaccaccggcatcgagttcatgcacatccaggacccgaagcagcgc
aagtggatccaggaccgggtggagcgcggtccgggcaagcccgagcgcgaggagcagctg
cgcatcctgcggcggctcaacagcgccgaggcgttcgagaccttcctgcagaccaagtac
gtcggccagaagcggttctcgctggagggcggcgagtccgtcatcccgctgctcgacgcg
gtcctggactcggcggccgaggcgcggctggacgaggtcgtcgtcggcatggcccaccgc
ggccgcctcaacgtcctcgccaacatcgtcggcaagtcgtacgcgcagatcttccgggag
ttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtcaagtaccacctg
ggcgccgagggcaccttcaccggcctggacggcgagcagatcaaggtctcgctcaccgcc
aacccctcccacctggaggcggtcgacccggtcatggagggcgtggtccgcgccaagcag
gacatcatcaacaagggcggcacggacttcaccgtcctgcccgtcgccctccacggtgac
gcggccttcgcgggccagggcgtggtggccgagacgctcaacatgtcgcagctgcgcggc
taccgcaccggcggcacggtccacatcgtcatcaacaaccaggtcggcttcaccgccgcg
ccggagtcctcgcgctcctcgatgtacgccaccgacgtggcccgcatgatcgaggcgccg
atcttccacgtgaacggtgacgacccggaggccgtcgtccgcgtcggacggctcgccttc
gagttccgccaggcgttcaacaaggacgtcgtcatcgacctgatctgctaccgccgccgc
ggccacaacgagtcggacaacccggccttcacccagccgctgatgtacgacctgatcgac
aagaagcgctcggtgcgcaagctctacaccgagtcgctgatcggccggggcgacatcacc
ctcgaagaggcggagcaggcgctccaggacttccagggccagctggagaaggtcttcacc
gaggtccgcgaggccacctcgcacccggtggagcacgagccggagggccccgaggcggag
ttcccggtcacggtcaacaccgcggtctccccggaggtcgtcaagcggatcgccgagtcg
caggtcaacatccccgagcgggtcaccgtccacccccgtctgctgccgcagctccagcgc
cgcgcggcgatggtcgaggacggcacgatcgactggggcatgggcgagaccctggccatc
ggctcgctgctgatggagggcaccccggtgcgcctctccggccaggactcgcgccgcggc
accttcggccagcgccacgcggtcctcatcgaccgggagaccggcgacgactacacgccg
ctgctgtacctctcggacaaccaggcccgctacaacatctacgactcgctgctctccgag
tacgcggcgatgggcttcgagtacggctactcgctggcccgtccggagtcgctggtgctg
tgggaggcccagttcggtgacttcgtcaacggcgcgcagaccgtcgtcgacgagttcatc
tcctcggccgagcagaagtggagccagcactccggtgtgacgctgctgctgccgcacggc
tacgagggccagggcccggaccactcctcggcccgcccggagcggttcctccagctctgc
gcgcagaacaacatgacggtcgccatgccgaccctcccgtcgaactacttccacctcctg
cggtggcaggtgcacaacccgcaccacaagccgctggtggtcttcacgccgaagtcgatg
ctgcgcctgaaggccgccgcgtcgaaggcggaggagttcacgacgggcggcttccgcccg
gtcatcggcgacgactcggtggacgcctcgcaggtccgcaaggtcgtcctctgcgccggc
aaggtctactacgacctggaggccgagcggcagaagcgcggcgtcacggacaccgcgatc
atccgcgtcgagcgcctgtacccgctgccgggtgccgagctccaggcggagatcgccaag
tacccgaacgccgagaagttcctgtgggcccaggaggagccggcgaaccagggcttctgg
ccgttcatcgcgctcaacctgatcgaccacctggacctgggtgtcggcgcggacctcccg
gcggccgagcggctgcggcgcatctcgcgtccgcactcctcgtccccggcggtcggttcg
gccaagcgccaccaggccgaacaggcccagctggtcgccgaggtcttcgacgcctga
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