Streptomyces sp. HP-A2021: MQE23_30960
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Entry
MQE23_30960 CDS
T11535
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sthp Streptomyces sp. HP-A2021
Pathway
sthp00010
Glycolysis / Gluconeogenesis
sthp00020
Citrate cycle (TCA cycle)
sthp00620
Pyruvate metabolism
sthp00785
Lipoic acid metabolism
sthp01100
Metabolic pathways
sthp01110
Biosynthesis of secondary metabolites
sthp01120
Microbial metabolism in diverse environments
sthp01200
Carbon metabolism
sthp01210
2-Oxocarboxylic acid metabolism
Module
sthp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sthp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MQE23_30960 (aceE)
00020 Citrate cycle (TCA cycle)
MQE23_30960 (aceE)
00620 Pyruvate metabolism
MQE23_30960 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MQE23_30960 (aceE)
Enzymes [BR:
sthp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MQE23_30960 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
RL
Motif
Other DBs
NCBI-ProteinID:
UOB13200
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Position
complement(6849794..6852541)
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AA seq
915 aa
AA seq
DB search
MASASDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIPTKSEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAFLLDRLSEQHLDGFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARMNRYMHARGIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESIFRGA
GWNVIKLVWDRTWDPLLAQDRDGVLVNKMNTTPDGQFQTYATETGAYIRDHFFGDDHRLR
AMVEGMTDDQILHLGRGGHDHKKIFAAYKAAVEHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPISDKELESGVPPYYHPGPDSEEIQYMHDRRRGLGGYVP
TRVVRSKPLPLPEDKTYATVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRDLLLAYKEAPNGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMSDQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGFEIAHIVKDGLRRMYGGSEEHPHGEDVFYYLTVYNEPIQH
PAEPENVDVEGILKGVYRFSEGTGGSIPAQIMASGVAVPWAVEAQKILAEEWNVKADVWS
ATSWNELRREAVACEEHNLLHPEEEQRVPYVTRKLAGAEGPVVAVSDWMRSVPDQIARWV
PQTYQSLGADGFGFADTRGAARRFFHIDAQSIVVGVLTELAREGKVDRSVLKQAIDRYQL
LDVSAADPGVAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccgcatccgatcgcaacccgatcatcattggcggccttccgagtcaggttcct
gacttcgatcccgaagagacgcaggaatggctcgactccctcgacgccgccgtcgacgag
cgcggccgcgagcgcgcccgctatctgatgctgcggctgatcgagcgggctcgcgagaag
cgcgtggccgtgccggagatgcgcagcacggactacgtcaacaccatccccaccaagagc
gagccgttcttcccgggcaacgaggagatcgagcggaagatcctcaacgcgacccgctgg
aacgcggcggtgatggtctcccgggcccagcgccccggcatcggcgtcggcggccacatc
gccacgttcgcgtcctccgcctccctctacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccaggtcttcttccaggggcacgcctcgccgggcatc
tacgcccgcgccttcctgctggaccggctcagcgagcagcacctggacggcttccgccag
gagaagtcgaaggcgccctacggcctgtcgtcgtacccgcacccgcgcctcatgccggac
ttctgggagttcccgacggtgtcgatgggcctcggcccgatcggcgcgatctaccaggcg
cggatgaaccgctacatgcacgcgcgcgggatcgccgacacctcgaagtcgcacgtgtgg
gcgttcctcggcgacggcgagatggacgagcccgagtcgctgggccagctgtccatcgcc
gcccgcgagggcctggacaacctcacgttcgtcgtcaactgcaacctgcagcgcctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgatcttccgcggcgcc
ggctggaacgtgatcaagctggtctgggaccgcacctgggacccgctgctcgcccaggac
cgcgacggcgtgctggtcaacaagatgaacaccacgccggacggacagttccagacgtac
gccacggagaccggcgcgtacatccgcgaccacttcttcggtgacgaccaccgcctgcgc
gcgatggtcgagggcatgaccgacgaccagatcctgcacctggggcgcggcggtcacgac
cacaagaagatcttcgcggcgtacaaggcggccgtggagcacaagggccagccgacggtg
atcctcgccaagacgatcaagggctggacgctgggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccgcctgcac
ctgccgatctccgacaaggagctggagtccggcgtcccgccgtactaccacccgggcccg
gactcggaggagatccagtacatgcacgaccgccgcaggggtctcggcggttacgtcccc
acacgcgtcgtacggtccaagccgctgccgctgcccgaggacaagacgtacgcgaccgtg
aagaagggctcgggccagcagtcgatcgccacgacgatggccttcgtacgcctgctcaag
gacctcatgcgggacaaggagatcggcaagcggttcgtgctgatcgcgccggacgagtac
cgcacgttcggcatggactcgttcttcccgagcgcgaagatctacaacccgctcggccag
cagtacgagtcggtcgaccgtgacctgctgctcgcctacaaggaggcgccgaacggccag
atgctgcacgacggcatctcggaggcgggctgcaccgcgtccctgatcgccgccggctcg
gcctacgcgacccacggcgagccgctgatcccggtctacgtcttctactcgatgttcggc
ttccagcgcaccggcgaccagttctggcagatgtccgaccagctggcgcgcggcttcgtc
ctgggcgcgaccgccggccggacgacgctgaccggcgagggcctccagcacgccgacggc
cactcgcagctgctggcctccaccaaccccggctgcgtggcgtacgacccggcgttcggt
ttcgagatcgcccacatcgtgaaggacggcctgcgccggatgtacggcggctccgaggag
cacccgcacggcgaggacgtcttctactacctgaccgtctacaacgagccgatccagcac
ccggccgagcccgagaacgtggacgtcgagggcatcctcaagggcgtctaccgcttcagc
gagggcaccggcggctcgatcccggcgcagatcatggcgtcgggtgtcgcggtgccgtgg
gcggtcgaggcgcagaagatcctggccgaggagtggaacgtcaaggccgacgtctggtcg
gcgacctcctggaacgagctgcggcgcgaggctgtggcctgcgaggagcacaacctgctg
cacccggaggaggagcagcgggtgccgtacgtgacgcggaagctggcgggcgcggagggc
ccggtcgtggccgtgtccgactggatgcgatcggttccggaccagatcgcgcgctgggtg
ccgcagacgtaccagtcgctcggcgcggacggcttcggcttcgcggacacgcggggcgct
gcccgccgcttcttccacatcgacgcgcagtcgatcgtggtgggggtgctgaccgagctg
gcccgtgagggcaaggtcgaccggtcggtgctcaagcaggccatcgaccggtaccagctg
ctcgacgtgtcggcggccgacccgggggtcgcgggcggcgacgcgtaa
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