Streptomyces sp. HP-A2021: MQE23_32105
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Entry
MQE23_32105 CDS
T11535
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sthp Streptomyces sp. HP-A2021
Pathway
sthp00010
Glycolysis / Gluconeogenesis
sthp00020
Citrate cycle (TCA cycle)
sthp00620
Pyruvate metabolism
sthp00785
Lipoic acid metabolism
sthp01100
Metabolic pathways
sthp01110
Biosynthesis of secondary metabolites
sthp01120
Microbial metabolism in diverse environments
sthp01200
Carbon metabolism
sthp01210
2-Oxocarboxylic acid metabolism
Module
sthp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sthp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MQE23_32105 (aceE)
00020 Citrate cycle (TCA cycle)
MQE23_32105 (aceE)
00620 Pyruvate metabolism
MQE23_32105 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MQE23_32105 (aceE)
Enzymes [BR:
sthp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MQE23_32105 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
UOB13409
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Position
complement(7105487..7108189)
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AA seq
900 aa
AA seq
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MTDPNAIQPSELDQLPDRDPEETAEWQASLDAVTEAAGPHRAAYLMRRTLERAEGAGIAL
PKLLETDYVNSIPTAAEPAVPGDEAMEQRITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFKGKEADGSGDQLYIQGHASPGIYARAFLDGRLTEEQLDNFRREAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDTSASHVWAFLGDGEM
DEPESTAALALAAREELDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKTL
WGTAWDELFQLDTTGALVRRLRQVPDAQIQTYQTRDAAYIRQDFFGADPALAELAKLLSD
DKILECFHFSRGGHESRKVYAAYKAAVEHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLTVDEFKNMRDLLGLPIKDSDFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH
PAAPLPAPAEKAFASFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTSYAT
HGETMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEVAVIVKDGLRRMYGEAAPGEDQNVFYYLTVYNEPLPQPAKPS
VDGIDEGIVKGLYRFNTAESAGITPPANAPRIQLLGSGTAIHWALKAQALLAEEWGVAAD
VWSATSWSELRRDALEADEALLRGEERMPFVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDWSSLGADGFGLSDTREAARRHFGVDAESIVVAALAQLAGRGEVKATAVKEARAKYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgagctcgaccagctcccggaccgggacccg
gaggagaccgccgaatggcaggcctccctggacgcggtgaccgaggcggccgggccgcac
cgtgccgcgtacctgatgcggcgcacgctggagcgtgccgagggcgccggcatcgcgctg
ccgaagctcctggagaccgactacgtcaactccatccccaccgccgccgagccggccgtg
cccggtgacgaggcgatggagcagcggatcaccgcgtggaaccgctggaacgcggccgcg
atggtcacccggggcagcaagtacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttcaaaggcaaagaggccgacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgcgttcctc
gacggccgtctgaccgaggagcagctcgacaacttccgccgcgaggcgggcggcaacggc
ctgccctcctacccgcacccgcgccgcctgccctggctgtgggagttcccgaccgtctcc
atgggtctgggcccgctctccgccatctaccaggcgcgcttcaaccgctacctcaccaac
cgcggcatcaaggacacctccgcctcgcacgtgtgggcgttcctcggcgacggcgagatg
gacgagcccgagtcgacggcggcactcgcgctggcggcccgtgaggagctggacaacctc
accttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttcaag
atcgtgcaggagttggaggcccagttccgaggcgccggctggaacgtcgtcaagacgctg
tggggcacggcctgggacgagctgttccagctcgacaccacgggcgcgctggtacgccgt
ctgcgccaggtaccggacgcgcagatccagacgtaccagacccgcgacgcggcctacatc
cgccaggacttcttcggcgccgacccggcgctggcggagctggcgaagctgctgagcgac
gacaagatcctcgagtgtttccacttctcgcgcggtggtcacgagtcccgcaaggtgtac
gccgcgtacaaggcggccgtcgagcacaagggcgcaccgacggtgatcctggcccagacg
gtcaagggccacaccctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaagaacatgcgcgacctgctcggcctgccgatcaaggac
agcgacttcgtcgacggcgtggtcccctacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcggcgtgccgccctcggcggtccggccccggcccgccgcgtccac
ccggccgcgccgctgcccgccccggcggagaaggcgttcgcgtccttcgacaagggctcg
ggttcgcagaacgtggcgacgacgatggcgttcgtccgcctggtcaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtcccggacgaggcgcgcaccttcggt
atggagagcctcttcccgtccctgggcatctactcgcccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccaagaacggccagatcctcaacgag
gggatcaccgaggccggttcgatggccgacttcatcgccgcctcgacgtcgtacgcgacg
cacggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggcgccacg
gcgggccgcacgacgctgaccggtgagggcctccagcacgccgacggccactcccccgtc
atcgccgcgacgaacccggcggcgctgacatacgacccggcgttcgcgtacgaggtcgcg
gtcatcgtcaaggacggtctgcgccggatgtacggcgaggcggccccgggtgaggaccag
aacgtcttctactacctgaccgtctacaacgagccgctgccgcagcccgcgaagccgtcc
gtggacggcatcgacgagggcatcgtcaagggcctgtaccgcttcaacacggcggagtcg
gcgggcatcacgcccccggccaacgccccgcggatccagctgctcggctccggtacggcg
atccactgggcgctgaaggcgcaagcgctgctcgccgaggagtggggcgtggcggccgac
gtgtggtcggcgacctcgtggagcgagctgcgccgggatgccctggaggcggacgaggcg
ctgctgcgcggcgaggagcggatgccgttcgtccggcaggcgctccagggtgccgagggc
ccggtgctggcggtctccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactggtcctcgctgggcgccgacggcttcggcctctcggacacccgtgaggcg
gcccgccgccacttcggcgtcgacgccgagtcgatcgtcgtcgcggccctggcacagctc
gcggggcgcggcgaggtcaaggcgacggccgtgaaggaagcgcgcgcgaagtacggcctg
taa
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