Streptomyces sp. HP-A2021: MQE23_34140
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Entry
MQE23_34140 CDS
T11535
Symbol
cobJ
Name
(GenBank) precorrin-3B C(17)-methyltransferase
KO
K13541
cobalt-precorrin 5A hydrolase / cobalt-factor III methyltransferase / precorrin-3B C17-methyltransferase [EC:
3.7.1.12
2.1.1.272
2.1.1.131
]
Organism
sthp Streptomyces sp. HP-A2021
Pathway
sthp00860
Porphyrin metabolism
sthp01100
Metabolic pathways
sthp01240
Biosynthesis of cofactors
Module
sthp_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
sthp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MQE23_34140 (cobJ)
Enzymes [BR:
sthp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.131 precorrin-3B C17-methyltransferase
MQE23_34140 (cobJ)
2.1.1.272 cobalt-factor III methyltransferase
MQE23_34140 (cobJ)
3. Hydrolases
3.7 Acting on carbon-carbon bonds
3.7.1 In ketonic substances
3.7.1.12 cobalt-precorrin 5A hydrolase
MQE23_34140 (cobJ)
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Motif
Pfam:
TP_methylase
CbiG_C
CbiG_N
DUF8611
Motif
Other DBs
NCBI-ProteinID:
UOB13792
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Position
complement(7556654..7558336)
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AA seq
560 aa
AA seq
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MIGLISATAAGAAARDRLAAAWPDRTRVYEGPVGDAVGAAFAQCEQLVCFLATGAVVRLV
APLLSGKTADPGVVCVDEGGRFAVSLVGGHAGGANELAREVAEVLGAEPVVTTATDAADL
PGLDTLGLPVEGDVAGVSRALLDGEAVALRAEVAWPLPPLPVAAEGSYTIRLTDRLVETA
ERQVVLRPPSLVVGVGASKGAPVEEVLGLIEGVLREAGLSAASVAELATVDAKAEEPGIV
EAARRVGVPLVTYSAGELAAVDVPNPSDAPLAAVGTPSVAEAAALVSGGELLVPKRKSAA
SPAMATCAVVRRPGRGRLAVVGLGPGARDLLTPRAKAELRRASVLVGLDQYVEQIRDLLR
PGTRILESGLGAEEERARTAVEEARKGRAVALIGSGDAGVYAMASPALAEASDDIDVVGV
PGVTAALAAGAILGAPLGHDHVSISLSDLHTPWEVIERRVRAAAEADIVVTFYNPRSRGR
DWQLPKALDILAEHRAPTTPVGVVRNASRPDESARLTTLAALDPATVDMMTVVTVGNTAT
REIAGRMVTPRGYRWQEEPE
NT seq
1683 nt
NT seq
+upstream
nt +downstream
nt
gtgatcggcctcatctccgccacggcggcaggagcggctgcgcgggaccggctggccgcc
gcgtggccggaccgcacgcgcgtgtacgagggtcccgtcggggacgccgtaggggccgcg
ttcgcacagtgcgagcagctcgtgtgcttcctggcgaccggcgcggtggtgcggctggtg
gcgccgctgctgtccggcaagacggcggacccgggcgtggtgtgcgtcgacgagggcggc
cggttcgcggtgtccctggtgggcgggcatgccggcggagccaacgaactcgcccgagaa
gtcgcggaggtgctgggtgccgagccggtcgtgaccacggcgacggacgcggcggacctg
cccggcctggacaccctcggcctgcccgtggagggcgatgtcgccggggtctcccgggcg
ttgctggacggtgaggcggtggcgctgcgggccgaggtggcctggccgctgccgccgctc
ccggtggccgccgaggggtcgtacacgatccggctgaccgaccggctcgtcgagacggcc
gagcggcaggtggtgctgcgcccgccgtcgctggtcgtcggggtcggggcgtcgaagggc
gcacccgtcgaggaagtgctcgggctgatcgagggcgttctgcgggaggccgggctgtcc
gcggcgtcggtcgccgagctcgccaccgtcgacgccaaagcggaggagcccggcatcgtc
gaggccgcccggcgggtcggtgtgcccctggtgacgtactccgccggggagttggccgca
gtcgacgtgcccaatccgtccgacgcgcccctggccgccgtcggcaccccctcggtcgcg
gaggccgccgccctggtgagcgggggcgaactcctcgtccccaagcggaagtcggccgcg
agccccgccatggcgacctgtgccgtcgtacggcgcccggggcgcgggcggctcgcggtg
gtcgggctcgggccgggtgcccgggacctgctcacgccgcgcgcgaaggcggaactccgg
cgcgcttccgtgctcgtcggactcgaccagtacgtcgagcagatccgcgatctgctgcgg
cccggcacccggatcctggagtcgggcctcggggccgaggaggagcgggcgcgcacggcc
gtcgaggaggcccgcaaggggcgggccgtcgcgctgatcggcagcggggacgcgggcgtg
tacgccatggcctcgcccgcgctcgccgaggcctccgacgacatcgacgtggtcggtgtg
cccggcgtgacggcggcgctcgcggccggcgcgatcctgggcgccccgctgggccacgac
cacgtgtcgatcagcctgtccgacctgcacacgccgtgggaggtcatcgagcggcgggta
cgggcggcggccgaggccgacatcgtggtgacgttctacaacccgcgctcgcgcggccgc
gactggcagctgcccaaggcgctggacatcctcgccgagcaccgggcgccgacgacgccg
gtcggtgtcgtgcgcaacgcctcgcggccggacgagtccgcccggctcacgacgctggcc
gcgctcgacccggcgacggtcgacatgatgacggtcgtcaccgtgggcaacaccgcgacc
cgcgagatcgccgggcgcatggtgacgccgcgcggctaccgctggcaggaggagcccgag
tga
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