Streptomyces sp. HU2014: M1P56_22550
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Entry
M1P56_22550 CDS
T11358
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
sthu Streptomyces sp. HU2014
Pathway
sthu00909
Sesquiterpenoid and triterpenoid biosynthesis
sthu01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
sthu00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
M1P56_22550 (shc)
Enzymes [BR:
sthu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
M1P56_22550 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
M1P56_22550 (shc)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Motif
Other DBs
NCBI-ProteinID:
UQI46932
LinkDB
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Position
complement(5295197..5297200)
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AA seq
667 aa
AA seq
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MTATTDGSTGAPPLPAAAAKDSTTVTPPPDGGPAAATTAAERATARAVDHLLSRQDPEGW
WKGDLQTNVTMDAEDLLLRQFLGIQDERTTRAAALFIRSEQRPDGTWATFLGGPPELSAT
IEAYVALRLAGDAPDAPHMATASAWIRAQGGIAASRVFTRIWLALFGWWKWDDLPELPPE
IMYVPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPRRPNPPRPLAP
ATSWDGVFQRLDKALHRYRRFPVKPLRRAALNAAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLDHPVLRAGLASLDRFAVWREDGSRMIEACQSPVWDTCLAAIALADAGVAPD
HPALVKAADWMLDEQILRPGDWTVRRPELPPGGWAFEFHNDNYPDIDDTAEVVLALKRVA
HPDRARLDAAVERAARWNLGMQSKDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVLGRQHDPRTRRGIEWLLAEQEENGGWFGRWGVNYVYGTGSVVPALVTAGLP
ASHPAIRRAVRWLESVQNDDGGWGEDLRSYRDPEWIGRGASTPSQTAWALMALLAAGERD
GKAVERGVARLVETQAEDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPF
AADRQEA
NT seq
2004 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggagcccctccgctccccgcagccgcggccaag
gacagcaccaccgttacgcccccgcccgacggcgggccggcggcggccacgacggccgcc
gagcgggccaccgccagggcggtcgaccacctcctgtcccggcaggaccccgaggggtgg
tggaagggcgacctccagaccaacgtcaccatggacgccgaggacctgctcctccgccag
ttcctcgggatccaggacgagcggaccacccgcgccgccgccctcttcatccgctccgag
cagcggcccgacggcacctgggccaccttcctcggcggaccgcccgaactctcggccacc
atcgaggcctatgtcgcgctgaggctcgccggggacgcccccgacgccccgcacatggcc
accgcctccgcctggatccgcgcgcagggcggcatcgccgcctcccgggtcttcacccgc
atctggctggccctcttcggctggtggaagtgggacgacctgccggagctgccgcccgag
atcatgtacgtgccgaagtgggtcccgctcaacatctacgacttcggctgctgggcccgg
cagaccatcgtgccgctcaccgtcgtctcggcgaagcggcccgtgcgccccgcgcccttc
gcgctggacgagctgcacaccgacccgcgccggccgaacccgccccgcccgctcgccccg
gccaccagctgggacggcgtcttccagcgcctggacaaggcgctccaccggtaccgcagg
ttccccgtcaagcccctgcgccgcgccgcgctcaacgccgcagcccgctggatcatcgag
cgccaggagaacgacggctgctggggcggcatccagccacccgccgtctactccgtcatc
gccctgcacctcctcggctacgacctcgaccaccccgtgctgcgcgcgggcctcgcgtcg
ctggaccgtttcgccgtctggcgcgaggacggctcgcggatgatcgaggcgtgtcagtcc
ccggtgtgggacacctgtctcgccgcgatcgcgctcgccgacgcgggcgtggccccggac
cacccggcgctcgtcaaggccgccgactggatgctcgacgagcagatcctccggcccggc
gactggacggtgcgcaggccggaactgcccccgggcggctgggccttcgagttccacaac
gacaactaccccgacatcgacgacaccgccgaggtcgtcctcgcgctcaagcgcgtcgcc
catcccgaccgcgcccggctggacgcggccgtggagcgcgccgcccgctggaacctgggc
atgcagtcgaaggacggcgcctggggcgccttcgacgccgacaacaccagccccttcccc
aaccggctgccgttctgcgacttcggcgaggtcatcgacccgccgtccgccgacgtcacc
gcgcacgtggtggagatgctggccgtcctcggcaggcagcacgacccgcgcacccggcgc
ggcatcgagtggctgctcgccgagcaggaggagaacggcggctggttcggccgctggggc
gtcaactacgtctacggcaccgggtcggtcgtccccgccctcgtcaccgccgggctcccc
gcctcgcacccggcgatccgccgggccgtgcgctggctggagagcgtgcagaacgacgac
ggcggctggggcgaggacctgcgctcgtaccgcgacccggagtggatcggccgcggcgcc
tccaccccctcccagacggcctgggccctgatggccctgctcgccgcgggggagcgggac
ggcaaggcggtcgagcgcggggtggcccggctggtggagacccaggccgaggacggctcc
tgggacgagccgcacttcaccggcaccggcttcccctgggacttctccatcaactaccac
ctgtaccgccaggtcttccccctcacggccctcggccgctacgtccacggggagcccttc
gccgccgaccgccaggaggcgtga
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