Streptomyces sp. HU2014: M1P56_28085
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Entry
M1P56_28085 CDS
T11358
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sthu Streptomyces sp. HU2014
Pathway
sthu00020
Citrate cycle (TCA cycle)
sthu00630
Glyoxylate and dicarboxylate metabolism
sthu00785
Lipoic acid metabolism
sthu01100
Metabolic pathways
sthu01110
Biosynthesis of secondary metabolites
sthu01120
Microbial metabolism in diverse environments
sthu01200
Carbon metabolism
sthu01210
2-Oxocarboxylic acid metabolism
Module
sthu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sthu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sthu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
M1P56_28085
00630 Glyoxylate and dicarboxylate metabolism
M1P56_28085
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M1P56_28085
Enzymes [BR:
sthu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
M1P56_28085
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
M1P56_28085
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
M1P56_28085
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
M1P56_28085
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UQI47920
LinkDB
All DBs
Position
6702739..6706560
Genome browser
AA seq
1273 aa
AA seq
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MSPQSPNTSSISTGQDGQGKSPADVFGSNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GQAAAAPPTALTGATPPQPARPAAAPVAAQAAPAAAPAAPAQPAPAQAAPAAPVAKAPAA
PQQAPAKPAAAAPAKPAAKAPEKAAPATEAPAGPEYVTLRGPSAAVAKNMNASLELPTAT
SVRAVPVKLLFDQRIVINNHLKRARGGKVSFTHLIGYAMVQALKLMPSMNHSFTEKDGKP
TLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARVGKLTMD
DFTGVTASLTNPGGIGTVHSVPRLMPGQGLILGVGAMDYPAEFQGTSQDALNRMGISKVM
TLTSTYDHRVIQGAASGEFLRIMAQLLLGENDFYDEIFKALRIPYEPVRWLRDIDVSHDD
DVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFA
GKAMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERGHSKPEREEQLRILRR
LNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDAAAESRLDEVVIGMAHRGRLNV
LANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHL
ETVDPVVEGIARAKQDIIGKAGTDFTVLPVQLHGDAAFAGQGVVAETLNMSQLRGYRTGG
TVHIVINNQVGFTAPPESSRSSMYCTDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQA
FNKDVVIDLICYRRRGHNESDNPGFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAE
QALQDYQGQLEKVFIEVRQADTAPAPLEVPAPQTGFPVQVDTAISQEVVKRIAESQVTLP
DGVTVHPRLLPQLQRRAASVEDGTIDWGMGETLAFGSLLMEGTPVRLAGQDSRRGTFGQR
HAVLVDRETGDDYTPLLYLSEDQARYNVYDSLLSEYAAMGFEYGYSLARPDALVLWEAQF
GDFVNGAQSIIDEFISSSEQKWNQTSGVTLLLPHGYEGQGPDHSSARVERFLQLCAQDNM
TVAMPTSPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKAEEFTTGSFRPVIGDD
TVATADVRKVVFCSGKVYYDLIAERDKRGANDTAIVRIERLYPLPGAELQAEIAKYSGAE
KYIWAQEEPANQGAWPFIALNLIDHLDLAVGADIPARERLRRISRPHSSSPAVGSAKRHQ
VEQQALVAEVFDA
NT seq
3822 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccaacacctcgagcatctcgacaggccaagacgggcagggcaag
agccctgcggatgtcttcggctccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtcgaccgagcctggtgggacttcttcgccgactacaagccc
ggccaggccgcggccgcgccgccgacggcgctgacgggggccacgcccccgcagcccgcc
cggcccgccgccgcgcccgtcgcggcgcaggcggctccggccgccgctccggctgccccc
gcgcagcccgccccggcccaggccgccccggccgcgccggtcgccaaggctccggccgcc
ccgcagcaggctcccgccaagccggccgcggccgcgccggcgaagcccgccgcgaaggca
cccgagaaggccgctccggccaccgaggcgcccgccggtcccgagtacgtgacgctgcgc
ggcccctcggccgccgtcgccaagaacatgaacgcctccctggagctgccgacggccacg
tccgtccgcgcggtcccggtgaagctgctgttcgaccagcgcatcgtgatcaacaatcac
ctcaagcgcgcccgcggtggcaaggtctccttcacgcacctcatcggctacgccatggtg
caggcgctgaagctcatgccgtccatgaaccactccttcacggagaaggacggcaagccg
accctcgtcaagcccgagcacgtcaacctcggcctggcgatcgacctggtcaagcccaac
ggtgaccgccagctcgtggtcgcggccatcaagaaggccgagacgctcaacttcttcgag
ttctggcaggcgtacgaggacatcgtccgccgcgcccgcgtcggcaagctgacgatggac
gacttcaccggcgtcaccgcctcgctgaccaaccccggcggcatcggcaccgtgcactcc
gtgccgcgcctgatgcccggccagggtctgatcctcggcgtcggcgcgatggactacccg
gccgagttccagggcacctcgcaggacgccctgaaccgcatgggcatctccaaggtcatg
accctgacctcgacgtacgaccaccgcgtgatccagggcgccgcctccggcgagttcctg
cggatcatggcccagctgctgctcggcgagaacgacttctacgacgagatcttcaaggcc
ctgcggatcccgtacgagccggtccgctggctgcgcgacatcgacgtctcccacgacgac
gacgtcaccaaggccgcccgggtcttcgagctgatccactcctaccgggtccgcggccac
gtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctggacatc
accgagcacggcctcaccctgtgggacctggagcgcgagttcgcggtcggcggcttcgcc
ggcaaggcgatgatgaagctgcgcgacatcctgggcgtgctgcgcgactcgtactgccgc
accaccggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggatccaggac
cgggtggagcgcggccactccaagccggagcgcgaggagcagctgcgcatcctgcgccgg
ctgaacgccgccgaggccttcgagaccttcctccagacgaagtacgtcggccagaagcgc
ttctcgctggagggcggcgagtccgtcatcccgctgctcgacgcggtgctggacgcggcc
gccgagtcgcgcctggacgaggtcgtcatcggcatggcccaccgtggccgcctcaacgtc
ctcgccaacatcgtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaacctc
gacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcacc
ttcacgggcctggacggcgagcagatcaaggtctcgctggccgccaacccgtcgcacctg
gagaccgtcgacccggtcgtcgagggcatcgcccgcgccaagcaggacatcatcggcaag
gccggcacggacttcacggtcctccccgtccagctgcacggcgacgcggccttcgcgggc
cagggcgtcgtcgcggagacgctgaacatgtcgcagctgcgcggctaccgcaccggcggc
accgtgcacatcgtcatcaacaaccaggtcggcttcaccgcgccgccggagtcctcgcgc
tcgtcgatgtactgcaccgacgtcgcccggatgatcgaggcgccgatcttccatgtgaac
ggtgacgacccggaggccgtggtccgcgtcgcgcggctcgccttcgagttccgccaggcg
ttcaacaaggacgtcgtcatcgacctgatctgctaccgccgccgcggccacaacgagtcc
gacaacccgggcttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtg
cgcaagctgtacaccgagtccctcatcggtcgtggcgacatcacgctggaagaggccgag
caggcgctccaggactaccaggggcagctggagaaggtcttcatcgaggtccgccaggcc
gacacggccccggccccgctggaggtcccggccccgcagaccggcttcccggtccaggtg
gacaccgcgatctcccaggaggtcgtcaagcggatcgccgagtcgcaggtcaccctgccc
gacggcgtcacggtgcacccgcgcctgctgccgcagctccagcgccgcgcggccagcgtc
gaggacggcacgatcgactggggcatgggcgagaccctggccttcggttcgctgctgatg
gagggcaccccggtccggctcgccggccaggactcccgccgcggcaccttcggccagcgg
cacgcggtcctcgtcgaccgggagaccggcgacgactacaccccgctgctgtacctctcc
gaggaccaggcgcgttacaacgtctacgactcgctcctcagcgagtacgcggcgatgggc
ttcgagtacggctactccctggcccgcccggacgcgctggtgctgtgggaggcccagttc
ggtgacttcgtcaacggcgcccagtcgatcatcgacgagttcatctcctcctccgagcag
aagtggaaccagacctctggtgtcaccctgctgctgccgcacggctacgagggccagggc
ccggaccactcctcggcccgtgtcgagcgcttcctccagctctgcgcgcaggacaacatg
acggtcgccatgccgacgtcgccgtcgaactacttccacctgctgcgctggcaggtccac
aacccgcaccacaagccgctgatcgtcttcaccccgaagtcgatgctgcgtctgaaggcc
gcggcgtcgaaggcggaggagttcaccaccggttcgttccgtccggtgatcggtgacgac
accgtcgccacggcggacgtccgcaaggtcgtcttctgctccggcaaggtctactacgac
ctgatcgccgagcgggacaagcgcggcgcgaacgacacggccatcgtccgcatcgagcgg
ctgtacccgctgccgggtgccgagctccaggcggagatcgccaagtactccggcgcggag
aagtacatctgggcgcaggaggagccggcgaaccagggtgcctggccgttcatcgcgctc
aacctgatcgaccacctggacctggccgtgggtgccgacatcccggcccgggagcgactg
cgccggatctcccggccgcactcctcctccccggcggtcggctcggccaagcgccaccag
gtggagcagcaggctctggtcgccgaggtcttcgacgcctga
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