Streptomyces sp. ICC1: DRB96_20860
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Entry
DRB96_20860 CDS
T10586
Symbol
kgd
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
stii Streptomyces sp. ICC1
Pathway
stii00020
Citrate cycle (TCA cycle)
stii00630
Glyoxylate and dicarboxylate metabolism
stii00785
Lipoic acid metabolism
stii01100
Metabolic pathways
stii01110
Biosynthesis of secondary metabolites
stii01120
Microbial metabolism in diverse environments
stii01200
Carbon metabolism
stii01210
2-Oxocarboxylic acid metabolism
Module
stii_M00009
Citrate cycle (TCA cycle, Krebs cycle)
stii_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
stii00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
DRB96_20860 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
DRB96_20860 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DRB96_20860 (kgd)
Enzymes [BR:
stii01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
DRB96_20860 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
DRB96_20860 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
DRB96_20860 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
DRB96_20860 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AWZ14312
LinkDB
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Position
complement(4424827..4428726)
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AA seq
1299 aa
AA seq
DB search
MSPQSPSNSSTTTEAGGSGKNPAPGFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGAVAPVKADDPTEKPTPPPAATTTDGASAQAAASVTAATPQASDAAAATTTPVPAPAPV
PATPSGAPAVTVTSQAPAAAPAAPATPATPATPAPAPAAAPTTGAPTGPELVTLRGPAAA
VVKNMNASLEVPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKA
MPSMNYSFAEKDGKPTLVKPEHINFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAY
EDIVRRARVGKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQG
TSQDTLNKLGISKVMTLTSTYDHRTIQGAASGEFLRVVANMLLGESGFYDDVFEALRIPY
EPVRWLRDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYKQRKHPDLDITEHGL
TLWDLEREFAVGGFSGKSMMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRRWIQDRIERP
HSKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARL
EEVAIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGANGTFTGLD
GEQIKVSLVANPSHLEAVDPVLEGVVRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVA
ETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPE
AVVRIARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYT
ESLIGRGDITLEEAEQALQDFQGQLEKVFAEVREAATQPAAIPPIPAPQADFPVAMNTAI
SQEVVKRIAEAQVNIPDTVTVHPRLLPQLQRRAAMIDDGTIDWGMGETLAFGSLLMEGTP
VRLSGQDSRRGTFGQRHAVLIDRETGEDYTPLLYLSDDQARYNVYDSLLSEYAAMGFEYG
YSLARPDALVLWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHS
SARPERFLQMCAQDNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASK
AEEFTTGSFRPVIGDTRVSSGAGDPNEIRKVVFCAGKVYYDLEAEREKRGTTDAAARETA
IIRIERLYPLPGAELQAEIAKFPNAAKYIWAQEEPANQGAWPFIALNLIDHLDLAVGADI
PAGERLRRISRPHGSSPAVGSAKRHQAEQQLLMNEVFEA
NT seq
3900 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcaccacgaccgaagcaggagggagcgggaag
aaccccgccccaggcttcggtgccaatgagtggctcgtcgacgagatttatcagcagtac
ctccaggacccgaactcggtcgaccgggcctggtgggactttttcgccgactacaagccg
gggggcgctgtcgctccggtgaaggcggacgatcccacggagaagccgactcctcccccc
gccgcgacgacgacggacggcgcctccgcacaggccgccgcctccgtcaccgccgcgact
ccgcaggcttccgacgccgccgccgcgaccacgacacctgtgccagctcctgcccctgta
cctgccaccccctctggtgcccctgctgtgactgtcacctcccaggccccggccgccgca
ccggccgctcctgccactcctgccactcctgccactcctgctccggctcccgccgccgcg
cccaccactggggcccccacgggccccgaactggtgacgctccgcggcccggcggctgcc
gtggtcaagaacatgaacgcctcgctggaagtgccgacggccacgtccgtccgcgccgtc
ccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcccgc
ggtgggaagatctcgttcacccacctcatcggctacgcgatggtgcaggccatcaaggcc
atgccgtcgatgaactactccttcgcggagaaggacggcaagccgaccctggtcaagccg
gagcacatcaacttcggtctcgcgatcgacctggtgaagcccaacggcgaccgccagctc
gtcgtcgccggcatcaagaaggccgagaccctcaacttcttcgagttctggcaggcgtac
gaggacatcgtccgccgcgcccgcgtcggcaagctgacgatggacgacttcaccggggtg
acggtctccctcaccaaccccggcggcctgggcaccgtccactccgtgccccgcctgatg
cccggacagtcggtcatcatgggcgtcggctcgatggactaccccgcggagttccagggc
acctcgcaggacaccctgaacaagctgggcatctccaaggtcatgaccctgacctcgacg
tacgaccaccggaccatccagggcgcggcctccggcgagttcctgcgcgtcgtggcgaac
atgctgctcggcgagagcggcttctacgacgacgtcttcgaggcgctgcgcatcccgtac
gagccggtccgctggctccgggacatcgacgcctcgcacgacgacgacgtcacgaaggcc
gcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacacc
gacccgctggagtacaagcagcgcaagcaccccgacctcgacatcaccgagcacggcctc
accctgtgggacctggagcgcgagttcgcggtcggcggcttctccggcaagtcgatgatg
aagctccgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcgtcgag
ttcatgcacatccaggacccgaagcagcgccgctggatccaggaccgcatcgagcgcccg
cactccaagccggagcgcgaggagcagctgcggatcctgcgccggctgaacgccgcggag
gccttcgagaccttcctgcagacgaagtacgtcggccagaagcgcttctcgctggagggc
ggcgagtccgtcatcccgctgctcgacgccgtcatcgactcggccgccgaggcccgcctc
gaagaggtcgcgatcggcatggcccaccgcggccggctgaacgtgctcgccaacatcgtc
ggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtccatg
cacggctccggcgacgtcaagtaccacctgggcgccaacggcaccttcacgggcctggac
ggggagcagatcaaggtctcgctcgtcgcgaacccctcgcacctggaggcggtggacccg
gtcctggagggcgtcgtccgcgccaagcaggacatcatcaacaagggcggcacggacttc
acggtcctgcccgtcgccctgcacggcgacgcggccttcgcgggccagggtgtggtcgcc
gagacgctgaacatgtcgcagctgcgcggctaccgcaccggcggcaccgtgcacgtggtc
atcaacaaccaggtcggcttcaccgccgccccggagtcctcgcgttcctcgatgtacgcg
accgacgtggcccgcatgatcgaggcgccgatcttccacgtgaacggcgacgacccggag
gccgtggtccgcatcgcgcggctcgccttcgagttccgtcaggcgttcaacaaggacgtg
gtcatcgacctcatctgctaccgccgccgcgggcacaacgagtccgacaacccggcgttc
acgcagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtacacc
gagtccctcatcggtcgcggcgacatcaccctggaagaggccgagcaggcgctccaggac
ttccagggccagctggagaaggtcttcgcggaggtccgcgaggccgccacgcagcccgcg
gccatcccgccgatcccggccccgcaggccgacttcccggtggcgatgaacacggcgatc
tcccaggaggtcgtcaagcgcatcgccgaggcccaggtcaacatccccgacacggtcacc
gtccacccgcgcctgctgccgcagctgcagcgccgcgccgcgatgatcgacgacggcacc
atcgactggggcatgggcgagaccctcgccttcggctcgctgctgatggagggcaccccg
gtccggctgtccggccaggactcccgccgcggcacgttcggccagcgccacgcggtcctc
atcgaccgggagaccggcgaggactacaccccgctgctctacctgtcggacgaccaggcc
cgctacaacgtctacgactcgctgctctcggagtacgcggcgatgggcttcgagtacggc
tactcgctggcccgcccggacgcgctggtcctctgggaggcgcagttcggcgacttcgtc
aacggcgcgcagaccgtcgtcgacgagttcatctcctcggccgagcagaagtggggccag
acgtccggcgtcacgctcctcctgccgcacggctacgagggccagggcccggaccactcc
tccgcgcgccccgagcgcttcctgcagatgtgcgcgcaggacaacatgacggtggccatg
cccacgctcccgtcgaactacttccacctgctgcgctggcaggtccacaacccgcaccac
aagccgctcatcgtcttcaccccgaagtcgatgctgcgcctgaaggccgcggcgtcgaag
gcggaggagttcacgaccggttccttccgtccggtcatcggcgacacgcgcgtctcctcc
ggagccggtgacccgaacgagatccgcaaggtcgtcttctgcgcgggcaaggtctactac
gacctcgaggccgagcgggagaagcgcggtaccaccgacgctgcggctcgcgaaacggcg
attatccgcatcgagcggctgtacccgctgccgggcgcggaactccaggcggagatcgcc
aagttcccgaacgcggcgaagtacatctgggcccaggaggagccggcgaaccagggtgcg
tggccgttcatcgcgctgaacctgatcgaccacctcgacctggcggtcggcgcggacatc
ccggccggcgagcgcctgcgccgcatctcccgcccgcacggctcctcgccggcggtcggt
tcggccaagcgccaccaggcggagcagcagctcctcatgaacgaggtcttcgaggcgtag
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