Streptomyces tirandamycinicus: DDW44_06000
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Entry
DDW44_06000 CDS
T06843
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stir
Streptomyces tirandamycinicus
Pathway
stir00010
Glycolysis / Gluconeogenesis
stir00020
Citrate cycle (TCA cycle)
stir00620
Pyruvate metabolism
stir00785
Lipoic acid metabolism
stir01100
Metabolic pathways
stir01110
Biosynthesis of secondary metabolites
stir01120
Microbial metabolism in diverse environments
stir01200
Carbon metabolism
stir01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
stir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
DDW44_06000 (aceE)
00020 Citrate cycle (TCA cycle)
DDW44_06000 (aceE)
00620 Pyruvate metabolism
DDW44_06000 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DDW44_06000 (aceE)
Enzymes [BR:
stir01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
DDW44_06000 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AWI28390
UniProt:
A0A2S1SPT5
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Position
1358256..1361003
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AA seq
915 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETREWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGVYARAFLLDRLNETQLDAFRQ
EKSKFPDGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARMNRYMEARGIADTSRSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESIFRGA
GWNVIKLIWDRTWDPLLARDRDGVLVNKLNTTPDGQFQTYATETGDYIRRHFFGDDQRLR
AMVENMTDHQILMLGRGGHDHRKIFAAYSAARAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVDDLKGFRDRLHLPISDRELESGLPPYYHPGRDSEEIQYMHDRRKGLGGYVP
TRVVRSKPLALPDDKTYAAVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLSRGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACIAYDPAFGFEIAHIVQDGLRRMYGGDAEHPHGEDVFYYLTVYNEPIQH
PAEPENVDVDGILKGIHRFREGEAGRIPAQIMASGVAVPWALEAQRILAEEWDVKAGVWS
ATSWNELRREAVAAEEYNLLHPEEEQRVPYVTRKLGSAEGPFVAVSDWMRSVPDQIARWV
PGRYTSLGADGFGFADTRGAARRYFHIDAQSIVLAVLTELAHEGKVDRSVLKQAVDRYQL
LDVAAADPGPAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatcagatcgcaacccgatcatcattggcggccttccgagccaggtcccg
gacttcgatccggaggagacccgggagtggctcgactcgctcgacgccgccgtcgacgag
cgcggccgtgagcgggcccgctacctcatgctgcgactgatcgagcgggcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtgaacaccatcgcgaccaaggac
gagcccttcttcccgggcaacgaggagatcgagcggaaggtcctgaacgccacccgctgg
aacgccgcggtgatggtgtcccgcgcccagcgccccgggatcggcgtcggcggccacatc
gccaccttcgcctcctccgcgtccctctacgacgtgggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctcgcccggtgtc
tacgcccgcgcgttcctgctggaccggctgaacgagacccagctcgacgccttccgccag
gagaagtcgaagttccccgacggcctgtcgtcgtacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggcccgatcggggcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgccgacacctcccgctcgcacgtgtgg
gccttcctcggcgacggcgagatggacgagccggagtcgctcggccagctctcgatcgcc
gcccgcgagggcctggacaacctgaccttcgtggtgaactgcaacctgcagcggctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgatcttccgcggcgcc
ggctggaacgtgatcaagctgatctgggaccgcacctgggacccgctgctcgcccgggac
cgcgacggtgtgctggtcaacaagctgaacaccacgcccgacggccagttccagacgtac
gccacggagaccggcgactacatccgccggcacttcttcggcgacgaccagcggctgcgc
gccatggtcgagaacatgaccgaccaccagatcctgatgctgggccgcggcggccacgac
caccggaagatcttcgcggcgtactccgcggcccgcgcccacaagggccagccgacggtg
atcctcgcgcagacggtcaagggctggacgctgggaccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgacggtcgacgacctcaaggggttccgggaccggctgcac
ctcccgatcagcgaccgcgagctggagtccggcctgccgccgtactaccacccgggccgg
gactcggaggagatccagtacatgcacgaccgccgcaagggcctgggcgggtacgtgccg
acccgcgtggtgcggtcgaagccgctggccctgccggacgacaagacgtacgcggccgtg
aagaagggttccggccagcagtcgatcgccaccaccatggcgttcgtccggctgctgaag
gacctcatgcgggacaaggagatcggcaagcggttcgtgctgatcgcaccggacgagtac
cgcacgttcggcatggactcgttcttcccgagcgcgaagatctacaacccgctcggccag
cagtacgaggccgtggaccgcgagctgctcctcgcgtacaaggagtcgccgaccgggcag
atgctgcacgacggcatctcggaggcgggctgcaccgcctcgctgatcgcggccggctcg
gcctacgccacccacggcgagccgctgatcccggtctacgtcttctactcgatgttcggt
ttccagcggaccggtgaccagttctggcagatggctgaccagctctcgcgcggattcgtc
ctcggtgcgaccgccgggcgcacgaccctgaccggtgagggtctgcagcacgcggacggc
cactcccagctgctggcctccaccaacccggcctgcatcgcctacgacccggcgttcggc
ttcgagatcgcgcacatcgtccaggacggcctgcgtcggatgtacgggggcgacgccgag
cacccgcacggcgaggacgtcttctactacctgaccgtctacaacgagccgatccagcac
ccggccgagcccgagaacgtcgacgtggacggcatcctcaagggcatccaccgcttccgg
gaaggcgaggcgggccggatcccggcacagatcatggcgtccggcgtcgccgttccctgg
gctctggaggcccagcggatcctcgccgaggagtgggacgtcaaggccggcgtctggtcg
gcgacctcctggaacgagctgcggcgcgaggccgtggcggcggaggagtacaacctgctc
caccccgaggaggagcagcgcgtcccgtatgtgacgcgcaagctcggcagcgccgaggga
ccgttcgtggccgtgtccgactggatgcgcagcgtcccggaccagatcgcccgctgggtg
cccggccgctacacctcgctgggtgccgacggcttcggcttcgcggacacccggggcgcg
gcccgccggtacttccacatcgacgcgcagtcgatcgtgctggcggtcctcaccgagctc
gcccacgagggcaaggtcgaccgctcggtgctgaagcaggccgtggaccgctaccagctg
ctggacgtggcggcggccgacccgggccccgcgggcggcgacgcctag
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