Streptomyces tirandamycinicus: DDW44_27260
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Entry
DDW44_27260 CDS
T06843
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
stir
Streptomyces tirandamycinicus
Pathway
stir00909
Sesquiterpenoid and triterpenoid biosynthesis
stir01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
stir00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
DDW44_27260 (shc)
Enzymes [BR:
stir01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
DDW44_27260 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
DDW44_27260 (shc)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
AWI32078
UniProt:
A0A2S1T0B2
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All DBs
Position
6246146..6248176
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AA seq
676 aa
AA seq
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MTATTDGSGGAPALRSPSASDHTTDHRPAPGDSAGLCTTALLTAQRSVEHLLGRQAPQGW
WKADLETNVTMDAEDLLLRQFLGVHDEKTTAAAAVFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDRPDDPHMERAAAWIRARGGIAASRVFTRIWLALFGWWKWEDLPELPPE
LIYLPSWFPLNIYDFGCWARQTIVPLTVVSATRPVRPAPFALDELHTDRHRPNPPRPLAP
AGSWDGVFQRLDRLLHGYRAVALRPLRRAAMNRAARWIIERQENDGCWGGIQPPAVYSLI
ALHLLGYDLDHPVMRAGLESLDRFAVWREGTAGPGDRREGPARMVEACQSPVWDTCLTVV
ALSDAGVPADHPALVRAADWMLGEQITRPGDWAVRRPRLAPGGWAFEFHNDNYPDIDDTA
EVVLALRRVKHPDPARVEEAVARAGNWTLGMQSKCGAWGAFDADNTGTFPNRLPFCDFGE
VVDPPSADVTAHVVEMLAQEGRAHHPRTRRGVDWLLREQEPHGAWFGRWGVNHLYGTGAV
VPALTAAGVPVSHPAIRRAVGWLESVQNDDGGWGEDLRSYREESWIGRGVSTPSQTGWAL
LALLAAGERDGSAVERGIAFLAATQREDGSWDERYFTGTGFPWDFSINYHIYRQVFPLMA
LGRYVHGQPPAGRNGD
NT seq
2031 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcggcggggcccccgcgctccgctcgccctcggccagc
gaccacaccaccgatcaccgtccggccccgggggactccgcgggcctgtgcaccaccgcc
ctgctgacggcgcagcgctccgtcgagcacctgctcggcaggcaggccccgcagggctgg
tggaaggccgacctcgagaccaatgtcaccatggacgccgaggacctgctgctccgtcag
ttcctcggcgtccacgacgagaagacgaccgcggccgcggccgtcttcatccgcggcgag
cagcgcgaggacggcacctgggccaccttctacggcggccccggcgaactctccaccacc
atcgaggcgtacgtcgccctccgcctcgccggcgaccggccggacgacccccacatggaa
cgcgccgccgcatggatccgggcgcggggcggcatcgccgcgagccgtgtcttcacccgc
atctggctggcgctcttcggctggtggaagtgggaggacctgcccgagctgccgcccgag
ctcatctacctcccctcctggttcccgctcaacatctacgacttcggctgctgggcccgc
cagaccatcgtgccgctcaccgtcgtctccgccacgcggcccgtacgccccgcgccgttc
gcgctcgacgaactgcacacggaccgccaccgccccaacccgccccggccgctcgctccc
gcgggcagctgggacggggtgttccagcgcctcgaccggctgctgcacggctaccgcgcg
gtggccctgcgcccgctgcgccgcgcggcgatgaacagggccgcccgctggatcatcgag
cggcaggagaacgacggctgctggggcggcatccagccgcccgccgtctactcgctgatc
gccctccatctgctcggctacgacctcgaccacccggtgatgcgggccggactggagtcg
ctggaccgcttcgccgtgtggcgtgaggggaccgccgggccgggtgaccggcgggagggc
ccggccaggatggtcgaggcctgccagtcgcccgtgtgggacacctgcctcaccgtcgtc
gcgctctccgacgccggggtgcccgcggaccacccggctctggtccgggccgccgactgg
atgctcggcgagcagatcacccggcccggcgactgggccgtgcgcaggccgcgtctcgcc
ccgggcggctgggcgttcgagttccacaacgacaactaccccgacatcgacgacacggcc
gaggtcgtcctggccctgcgccgggtgaagcacccggacccggcccgggtcgaggaggcc
gtcgcccgggccggcaactggacgctggggatgcagtcgaagtgcggagcctggggcgcc
ttcgacgccgacaacaccggcaccttccccaaccggctgccgttctgcgacttcggtgag
gtcgtcgaccccccgtccgcggacgtcaccgcgcacgtcgtggagatgctggcccaggag
ggccgggcccaccacccgcggacccgccgcggggtcgactggctgctgcgcgaacaggag
ccgcacggcgcctggttcggccggtggggcgtcaaccacctctacggcacgggcgcggtc
gtccccgcgctcaccgcggccggggtgccggtctcgcaccccgcgatccggcgggcggtc
ggctggctggagtccgtccagaacgacgacgggggctggggcgaggatctgcgctcgtac
cgcgaggagtcgtggatcggccgcggtgtctccaccccctcgcagaccggctgggccctg
ctggccctgctggccgcgggggagcgggacggcagcgcggtcgagcggggcatcgcgttc
ctcgccgccacccagcgcgaggacggctcctgggacgagcggtacttcaccggcaccggc
ttcccctgggacttctccatcaactaccacatctaccggcaggtgttcccgctgatggcc
ctcggccggtacgtgcacggacagccgcccgccggccggaacggtgactga
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