KEGG   Streptomyces tirandamycinicus: DDW44_27780
Entry
DDW44_27780       CDS       T06843                                 
Name
(GenBank) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
stir  Streptomyces tirandamycinicus
Pathway
stir00253  Tetracycline biosynthesis
stir01056  Biosynthesis of type II polyketide backbone
stir01100  Metabolic pathways
stir01110  Biosynthesis of secondary metabolites
Module
stir_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:stir00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    DDW44_27780
   00253 Tetracycline biosynthesis
    DDW44_27780
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:stir01004]
    DDW44_27780
   01008 Polyketide biosynthesis proteins [BR:stir01008]
    DDW44_27780
Enzymes [BR:stir01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     DDW44_27780
    2.3.1.260  tetracycline polyketide synthase
     DDW44_27780
Lipid biosynthesis proteins [BR:stir01004]
 Polyketide synthase
  Component type
   DDW44_27780
Polyketide biosynthesis proteins [BR:stir01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     DDW44_27780
    Nonaketide PKS
     DDW44_27780
    Decaketide PKS
     DDW44_27780
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_N
Other DBs
NCBI-ProteinID: AWI32176
UniProt: A0A2S1T0N5
LinkDB
Position
complement(6379739..6381007)
AA seq 422 aa
MTRRVAITGIGVVAPGGIGTKQFWQTITGGRTATRTITLFDPAPFRSRIAAECDFDAAEQ
GLSAEDAERLDRAAQFALVALREAVTDSGLEPGPDTAHRTGVSLGSAVGCTQKLEAEYVA
LSGGGREWLVDHTAASAHLYDHFVPSSMAAELAWEAGAEGPCTVVSAGCTSGLDSVGHAA
ALIREGSADVMIAGATDAPISPITVACFDAIRATSPRNDDPATALRPFDRTRNGFVLGEG
AAVLVLEELTAALRRGAHVYAEIAGYASRGNAYHMTGLRTDGRELAAAVGAALDEARLGP
ADLGYVNAHGTATKQNDVHETAALKRSLGAHAREIPVSSIKSMIGHSLGAIGSIEVAATA
LALENCVVPPTANLTEPDPELDLDYVPLHARERPMSAALTVGSGFGGFQSAMVLRRPEGR
AA
NT seq 1269 nt   +upstreamnt  +downstreamnt
gtgacccggcgggtggcgatcaccggtatcggtgtggtggcccccggcggcatcggcacc
aagcagttctggcagaccatcaccggcggccgcaccgccacccggaccatcaccctcttc
gacccggcccccttccgctccaggatcgcggccgagtgcgacttcgacgccgcggagcag
ggcctgagcgccgaggacgccgagcggctcgaccgggccgcgcagttcgccctggtcgcg
ctgcgcgaggccgtcaccgacagcggcctggaacccggccccgacaccgcgcaccgcacc
ggcgtcagcctgggcagcgcggtcggctgcacccagaagctggaagcggagtacgtggcc
ctgagcggcggcggacgggagtggctggtcgaccacaccgccgccagcgcgcatctgtac
gaccacttcgtgccgagctccatggccgccgagctcgcctgggaggccggcgccgagggc
ccctgcaccgtcgtgtcggccggctgcacctccggcctcgactcggtcgggcacgccgcc
gccctcatccgcgagggcagcgccgacgtgatgatcgccggggccaccgacgcccccatc
tccccgatcaccgtggcctgcttcgacgccatccgggccacctcgccccgcaacgacgac
ccggcgaccgcgctgcgccccttcgaccgcacccgcaacggcttcgtcctcggcgagggt
gccgcggtcctggtcctcgaggaactcaccgcggccctgcgccggggcgcccacgtgtac
gccgagatcgccggctacgcctcccgcggcaacgcgtaccacatgaccggactgcgcacg
gacggacgggagctggccgcggccgtcggcgccgccctcgacgaggcccggctcgggccc
gccgacctgggctacgtcaacgcccacggcaccgccaccaagcagaacgacgtgcacgag
accgcggccctcaagcggagcctcggagcgcacgcccgcgagatcccggtgagctccatc
aagtcgatgatcgggcactcgctgggcgccatcggctccatcgaggtcgccgccaccgcg
ctcgccctggagaactgcgtcgtcccgccgaccgccaacctcaccgagcccgacccggaa
ctcgacctggactacgtcccgctgcacgcccgggagcggcccatgtcggccgcgctcacc
gtgggcagcggcttcggcggcttccagagcgcgatggtgctgcgccggcccgaggggcgg
gccgcatga

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