Streptomyces sp. JL2001: ACE1OA_23895
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Entry
ACE1OA_23895 CDS
T11502
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stjl Streptomyces sp. JL2001
Pathway
stjl00010
Glycolysis / Gluconeogenesis
stjl00020
Citrate cycle (TCA cycle)
stjl00620
Pyruvate metabolism
stjl00785
Lipoic acid metabolism
stjl01100
Metabolic pathways
stjl01110
Biosynthesis of secondary metabolites
stjl01120
Microbial metabolism in diverse environments
stjl01200
Carbon metabolism
stjl01210
2-Oxocarboxylic acid metabolism
Module
stjl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stjl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
ACE1OA_23895 (aceE)
00020 Citrate cycle (TCA cycle)
ACE1OA_23895 (aceE)
00620 Pyruvate metabolism
ACE1OA_23895 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ACE1OA_23895 (aceE)
Enzymes [BR:
stjl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
ACE1OA_23895 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
XVL71810
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Position
complement(5362464..5365196)
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AA seq
910 aa
AA seq
DB search
MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATRDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAYLLDRLNETQLDAFRQ
EKSKYPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRDGILVNKLNSTPDGQFQTYATETGAYIRDHFFGDDQRLR
SMVENMSDQQILHLGRGGHDHRKIFAAFAAAKAHKGQPTVVLAQTVKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHIPITDKQLDEGYPPYYHPGRDSEEIQYMHDRRKALGGYVP
TRVVRAKPLTLPEDATYAAAKKGSGQQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCIAYDPAFGYEIAHIVKDGLRRMYGPDAEDVFYYLTVYNEPIQHPAEPE
DVDVEGILKGIHLHRRGETGSIPAQIMASGVAVPWAVEAQRILAEEWNVRADVWSATSWN
ELRREAVDVDRHNLLHPDEEQRVPYVTRKLSGAQGPFVAVSDWMRSVPDQISRWVPGAYT
SLGADGFGFADTRGAARRYFHIDAQSIVLAVLTELARDGKVDRSVLKQAVDRYQLLDVAA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttcccagccaggtcccg
gacttcgatcccgaagagacccaggaatggctcgactccctcgacgccgccgtcgacgag
cggggccgggagcgggcccgctacctgatgctccgcctgatcgagcgggcgcgcgagaag
cgtgtcgccgtgcccgagatgcgcagcacggactacgtgaacacgatcgccacccgggac
gagcccttcttccccggcaacgaggagatcgagcgcaaggtcctcaacgcgacccggtgg
aacgcggccgtgatggtctcgcgcgcccagcgcccgggcatcggggtcggcggccacatc
gccaccttcgcctcctcggcctcgctgtacgacgtcggcttcaaccacttcttccggggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctcccccggcatc
tacgcccgcgcctacctcctcgaccggctgaacgagacgcagctcgacgccttccgccag
gagaagtcgaagtacccgaacggcctgtcctcctacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggccccctcggcgcgatctaccaggcc
cggatgaaccggtacatggaggcgcgcggcatcgccgacacctccaagtcgcacgtctgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctcggccagctgtccatcgcc
gcccgcgagggcctggacaacctgaccttcgtcgtgaactgcaacctccagcgcctggac
gggccggtccgcggcaacggcaagatcatccaggagctggagtcgcagttccggggcgcc
ggctggaacgtcatcaagctggtctgggaccgctcctgggacccgctgctcgcacaggac
cgcgacggcatcctggtgaacaagctgaactcgacgccggacggccagttccagacgtac
gcgacggagaccggcgcgtacatccgcgaccacttcttcggcgacgaccagcggctgcgc
tcgatggtcgagaacatgtcggaccagcagatcctgcacctgggccgcggcggccacgac
caccgcaagatcttcgcggccttcgcggcggccaaggcccacaagggccagccgaccgtg
gtgctggcgcagacggtcaagggctggaccctcggcccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccggctgcac
atcccgatcacggacaagcagctggacgagggctacccgccgtactaccacccgggtcgc
gactcggaggagatccagtacatgcacgaccgccgcaaggcgctgggcgggtacgtcccg
acccgggtcgtgcgggcgaagcccctgaccctgcccgaggacgccacctacgcggcggcc
aagaagggctcggggcagcagtcgatcgccaccacgatggccttcgtccgcatcctcaag
gacctcatgcgggacaaggagatcggcaagcgtttcgtgctgatcgcccccgacgagtac
cgcaccttcggcatggacgcgttcttcccgagcgccaagatctacaacccgctgggccag
cagtacgaggccgtggaccgcgaactgctcctggcgtacaaggagtcgccgaccggccag
atgctgcacgacggcatctcggaggcgggctgcacggcctcgctgatcgccgcgggttcg
gcgtacgccacgcacggcgagccgctgatcccggtctacgtcttctactcgatgttcggc
ttccagcggaccggcgaccagttctggcagatggccgaccagctcgcgcgcggcttcgtg
ctcggcgcgaccgccggccgcacgaccctgaccggcgagggcctgcagcacgcggacggc
cactcgcagctgctcgcctcgacgaacccgggctgcatcgcctacgaccccgccttcggc
tacgagatcgcgcacatcgtcaaggacggcctgcgccggatgtacggccccgacgccgag
gacgtcttctactacctcaccgtctacaacgagccgatccagcaccccgcggagccggag
gacgtggacgtcgagggcatcctcaagggcatccacctccaccgtcgcggcgagaccggc
tcgatccccgcgcagatcatggcctccggtgtcgcggtgccgtgggcggtcgaggcacag
cggatcctcgccgaggagtggaacgtacgggccgacgtctggtcggcgacgtcgtggaac
gagctgcgccgcgaggccgtggacgtcgaccggcacaacctcctccaccccgacgaggag
cagcgcgtcccgtacgtgacgcggaagctctccggagcccagggtcccttcgtggcggtc
tcggactggatgcgctccgtccccgaccagatctcccgctgggtcccgggcgcctacacc
tcgctgggcgcggacggcttcggcttcgcggacacgcgcggtgcggcccgccgctacttc
cacatcgacgcccagtcgatcgtgctggcggtcctcaccgagctggcccgtgacggcaag
gtcgaccgctcggtcctgaagcaggccgtggaccgctaccagcttctcgacgtggcggct
gcggacccgggcgccgcgggcggcgacgcctag
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