Salmonella enterica subsp. enterica serovar Typhimurium LT2: STM0152
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Entry
STM0152 CDS
T00065
Symbol
aceE
Name
(RefSeq) pyruvate dehydrogenase, decarboxylase component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stm
Salmonella enterica subsp. enterica serovar Typhimurium LT2
Pathway
stm00010
Glycolysis / Gluconeogenesis
stm00020
Citrate cycle (TCA cycle)
stm00620
Pyruvate metabolism
stm00785
Lipoic acid metabolism
stm01100
Metabolic pathways
stm01110
Biosynthesis of secondary metabolites
stm01120
Microbial metabolism in diverse environments
stm01200
Carbon metabolism
stm01210
2-Oxocarboxylic acid metabolism
Module
stm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
STM0152 (aceE)
00020 Citrate cycle (TCA cycle)
STM0152 (aceE)
00620 Pyruvate metabolism
STM0152 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
STM0152 (aceE)
Enzymes [BR:
stm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
STM0152 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
PFO_beta_C
Motif
Other DBs
NCBI-GeneID:
1251670
NCBI-ProteinID:
NP_459157
UniProt:
Q8ZRT2
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Position
176240..178903
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AA seq
887 aa
AA seq
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MSERFQNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGAGASNY
INTIAVEDEPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDV
CFNHFFRARNEQDGGDLVYFQGHISPGIYARAFLEGRLTQEQMDNFRQEVHGNGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIVNELEGIFAGAGWNVIKVMWGGRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGKATVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADLEKLPYITFPEGSEEHKYLHERRQALHGYLPSRQPNFTEKLELPQLS
DFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNDLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPAGAEEGIRKGIYKLETL
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAITKFNIDADKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttccaaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgcgctcagtatctgattgaccaactg
ctttctgaagctcgtaaaggcggcgtgaaagtcgcggcaggcgcaggggccagtaattac
atcaacactattgccgttgaagacgaaccggaatacccgggtaatctggagctggaacgt
cgcattcgttctgcgatccgctggaacgccatcatgaccgtgctgcgcgcgtctaaaaaa
gaccttgagttgggcggccacatggcgtccttccagtcttccgccacgatctatgatgtc
tgttttaaccatttcttccgtgcgcgcaacgaacaggatggcggcgacctggtgtacttc
cagggccacatctctccgggcatctacgctcgcgcgttcctggaaggtcgtctgacccag
gaacagatggataacttccgtcaggaagttcacggcaatggcctctcttcctatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtctctatgggtctgggcccaatc
ggtgctatctaccaggcgaaattcctgaaatatctggaacaccgcggcctgaaagatacc
tctaaacaaaccgtttacgccttcctcggcgacggcgagatggatgagccggaatccaaa
ggcgcgatcaccatcgccacccgtgaaaaactggacaacctggtctttgttatcaactgt
aacctgcagcgtcttgacggcccggtcaccggtaacggcaagattgttaacgaactggaa
ggcatctttgcaggtgctggctggaacgttatcaaagtcatgtggggcggtcgttgggat
gaactgctgcgtaaagacaccagcggtaagcttatccagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatccaaagacggcgcttacgtgcgtgagcacttcttcggt
aaatacccggaaaccgcagccctggtggccgactggaccgatgagcagatttgggcgctg
aaccgcggtggtcacgatccgaagaaagtctatgctgcactgaaaaaagcgcaggaaacc
aaaggcaaagcgaccgtaatcctggcccataccattaaaggttacggcatgggcgacacc
gcggaaggcaaaaacatcgctcaccaggtgaagaaaatgaacatggacggcgtgcgttac
gtccgcgatcgtttcaacgtgccggttgccgatgctgatctcgaaaaactgccatacatt
accttcccggaaggttctgaagaacacaaatacctgcatgaacgccgtcaggcgctgcat
ggctacctgccaagccgtcagccgaacttcaccgagaagttagagctgcctcaactttca
gatttcggcgcgctgctggaagagcaaagtaaagagatttccactacgatcgctttcgtg
cgtgccctgaacgtgatgctgaagaacaagtcgatcaaagatcgtctggttccgatcatc
gccgacgaagcgcgtactttcggtatggaaggtctgttccgtcagattggtatctacagc
ccgaacggccagcagtacaccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagattctgcaggaaggtatcaacgagctgggcgcaggcgcatcctggctg
gctgcggcgacctcttacagcaccaacgatctgccgatgatcccgttctacatctactac
tctatgttcgggttccagcgtatcggcgacctgtgctggcaggctggcgaccagcaggct
cgcggcttcctgatcggcgggacttccggtcgtactacgctgaacggcgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcttacgac
ccggcttacgcttacgaagtggctgtcatcatgcatgatggtctggagcgtatgtacggt
gagaaacaagagaacgtttactactacatcaccacgctgaacgaaaactaccacatgccg
gccatgccagcaggtgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccctc
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtgcgt
gaagcagcacagatcctggcgaaagattacggcgtaggttctgacgtatatagcgtgacc
tccttcaccgaactggcgcgtgatggtcaggattgtgaacgctggaacatgctgcacccg
ctggaaaccccgcgcgttccgtacatcgctcaggtgatgaacgacgctccggctgtagca
tctactgactatatgaaactgttcgccgagcaggttcgtacttacgtaccggctgacgac
tatcgcgtactgggtacggatggcttcggccgttccgacagccgtgagaacctgcgtcac
cacttcgaagttgatgcttcttatgtggttgttgcagcgctgggcgaactggctaaacgt
ggcgaaatcgacaagaaagtggtagcggatgcgattaccaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa
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