Salmonella enterica subsp. enterica serovar Typhimurium LT2: STM4188
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Entry
STM4188 CDS
T00065
Symbol
metH
Name
(RefSeq) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
stm
Salmonella enterica subsp. enterica serovar Typhimurium LT2
Pathway
stm00270
Cysteine and methionine metabolism
stm00450
Selenocompound metabolism
stm00670
One carbon pool by folate
stm01100
Metabolic pathways
stm01110
Biosynthesis of secondary metabolites
stm01230
Biosynthesis of amino acids
stm04981
Folate transport and metabolism
Module
stm_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
stm00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
STM4188 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
STM4188 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
STM4188 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
STM4188 (metH)
04980 Cobalamin transport and metabolism
STM4188 (metH)
Enzymes [BR:
stm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
STM4188 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-GeneID:
1255714
NCBI-ProteinID:
NP_463053
UniProt:
P37586
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All DBs
Position
4408265..4412035
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AA seq
1256 aa
AA seq
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MSHVARCSLFRQHALCQYGSLRGALSGASVSSKVEQLRAQLNERILVLDGGMGTMIQSYR
LHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAM
ADYRMESLSAEINYAAAKLARACADEWTARTPEKPRFVAGVLGPTNRTASISPDVNDPAF
RNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMI
SGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTA
HPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLLPR
QLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQV
ESGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGK
GIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKILTEE
VGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRG
NDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERL
LDLAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIE
VIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEKGSSNGKMVI
ATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSGLITPSL
DEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALL
SDTQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVAHRLGV
QEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEK
LLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLADFVAPKL
SGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVY
WGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAM
WPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGYDAD
NT seq
3771 nt
NT seq
+upstream
nt +downstream
nt
atgtctcatgttgcccgttgttctcttttccgccagcacgctttgtgccagtatggctcg
ttacgtggagcgttgtcgggagcgagtgtgagcagcaaagttgaacaactgcgtgcgcag
ttaaatgaacgtattctggtgctggacggcggtatgggcactatgatccagagctatcgt
ctacatgaagaagatttccgcggggagcgctttgccgactggccctgcgacctgaaaggc
aacaatgacctgctggtcctcagcaagccggaggtgatcgccgctatccacaacgcctac
tttgaggctggcgcggatatcatcgaaaccaacacctttaactcgacaaccattgcgatg
gcggattaccggatggaatccctgtcggcggaaattaactatgcggcggccaaactggcg
cgcgcctgcgccgatgaatggacggcgcgaacaccagaaaaaccacgctttgttgcgggc
gtgcttggtccaactaaccgcacggcctccatttcgccggacgtcaacgacccggcgttt
cgtaatatcaccttcgatcagctggtggcggcctaccgtgaatccaccaaagcgctggtg
gaaggtggcgcagatctgattctgattgagaccgtttttgacaccctgaatgcgaaagcg
gcggtgtttgcggtgaaagaagagtttgaagcgctgggcgttgacctgccgatcatgatt
tccggcaccatcaccgacgcctctggccgtacgctttccggccagactaccgaagccttt
tataactcgctgcgccacgccgaggcgctcacttttggccttaactgcgcactggggcca
gatgaactgcgccagtacgtccaggaactgtcgcggattgccgaatgctacgtcaccgcg
cacccgaacgccggcctgccgaacgctttcggcgagtatgacctcgacgccgacaccatg
gcgaaacagattcgcgaatgggcggaagcgggcttcctgaatatcgttggcggctgctgc
ggcaccacgccggagcatattgcggcgatgagccgcgccgttgccggtttgctgccgcgc
cagctgccggatatcccggtcgcctgccgcctttccggcctggagccgctgaacattggc
gacgatagcctgtttgtgaacgtcggcgaacgtactaacgtcaccggctcggccaaattt
aaacggctgatcaaagaagagaaatacagcgaagcgctggatgtcgcccgtcagcaggta
gaaagcggcgcgcagattattgatatcaatatggatgaggggatgctcgacgccgaagcg
gcgatggtgcgtttcctcagcctgattgccggtgagccggacattgcccgtgtaccaatc
atgatcgactcctccaaatgggaggttatcgaaaaagggctgaagtgcattcagggtaaa
ggcatcgtcaactctatttcgatgaaagagggcgtggaagcctttattcatcatgcgaag
cttctgcgtcgctacggcgcggcagtggtggtgatggcctttgatgagcaggggcaggcc
gatacccgcgcgcgtaaaatcgaaatttgccgccgagcctacaaaattctcaccgaagag
gtgggtttcccgccggaagacatcatcttcgacccgaatatcttcgccgtggcgaccggt
attgaagagcacaacaactacgcgcaggactttatcggcgcttgcgaagacatcaaacgc
gagctgccgcacgcgctgatctccggcggcgtgtctaacgtgtccttctcgttccgcggc
aacgacccggtacgtgaggctatccacgcggtattcctctactacgccatccgcaacggt
atggacatgggcatcgtcaacgccggacagctggctatctacgacgacctgcccgccgag
ctgcgcgatgcggttgaagatgtcattcttaaccgtcgcgatgacggcactgagcgtttg
ctggatttggcggagaaataccgcggcagcaaaaccgacgaagctgccaacgcccagcag
gcggaatggcgtagctgggacgtgaaaaagcgtctcgaatactcgctggtgaaaggcatt
accgaatttatcgaacaggataccgaagaagcccgtcagcaggccgcccgcccgattgag
gtgattgaagggccgttgatggacggcatgaacgtggtcggcgacctgttcggcgaaggg
aaaatgttcctgccgcaggtggtgaaatccgctcgcgtgatgaaacaagcggtggcctac
ctggagccgtttattgaagccagcaaagaaaaaggctccagcaacggcaagatggtgatc
gccaccgtgaagggcgatgtgcacgatattggtaaaaatatcgttggcgtggtgctgcaa
tgtaacaactacgaaatcgtcgatcttggcgtgatggtgccagcggagaaaatcctcaga
acggcgcgtgaagtgaatgccgatctgatcggtctttccgggctgattaccccgtcgctg
gacgaaatggtcaacgtggcgaaagagatggagcgtcagggctttactatcccgctactg
atcggcggcgcaaccacttcgaaagcgcatacggcggtgaaaatcgagcagaactacagc
ggtccgacggtctacgtgcagaatgcttcgcgtaccgtgggcgtggtggcggcgctactc
tccgacacccagcgtgatgactttgtcgcccgtacccgcaaagagtacgaaaccgtgcgt
attcagcacgcccgcaaaaaaccgcgcacgccgccggtcacgctggaggcggcgcgcgat
aacgatctggcattcgattgggaacgctacaccccgccggtagcccaccgtctgggcgtg
caggaggtggaagccagcatcgaaactctgcgcaactatatcgactggacgccgttcttt
atgacctggtcgctggccggcaaatacccgcgcattctggaagatgaggtggtgggcgtt
gaggcgcagcgtctgtttaaagacgccaatgatatgctggataaactgagcgccgagaaa
ctgttgaatccgcgtggcgtggtgggcctgttcccggcgaaccgtgtgggtgacgacatc
gaaatctatcgcgacgaaacccgtactcatgttctgacggtcagccaccacctgcgccag
cagaccgagaaagtcggttttgccaactactgtctggcggattttgtcgcgccgaaactg
agcggcaaagcggattacatcggtgctttcgcggtgaccggcggtctggaggaggatgcg
ctggcggacgccttcgaagcgcaacacgacgactataacaagatcatggtgaaagcgatt
gccgaccgtctggcggaagcgttcgcggaatatctgcatgagcgtgtacgtaaggtttac
tggggatatgcgccgaacgagagcctgagtaacgacgaattaatccgcgaaaactaccag
gggattcgcccggcgccgggttatcctgcctgcccggaacataccgaaaaaggcactatc
tggcagctactggatgtcgaaaaacacaccgggatgaagctcaccgaatctttcgccatg
tggccaggcgcgtcggtctccggctggtacttcagccatcctgagagcaaatacttcgcg
gtagcgcagatccaacgcgatcaggtgacagattatgctttccgtaaaggaatgagcgtt
gaggatgttgagcggtggctcgcgccgaacctgggttacgatgcggactga
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integrated database retrieval system
