Sphaerodactylus townsendi (Townsend's least gecko): 125433778
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Entry
125433778 CDS
T08213
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
stow
Sphaerodactylus townsendi (Townsend's least gecko)
Pathway
stow04120
Ubiquitin mediated proteolysis
stow04144
Endocytosis
stow04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
stow00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
125433778 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
125433778 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
125433778 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
stow04131
]
125433778 (ITCH)
04121 Ubiquitin system [BR:
stow04121
]
125433778 (ITCH)
Enzymes [BR:
stow01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
125433778 (ITCH)
Membrane trafficking [BR:
stow04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
125433778 (ITCH)
Ubiquitin system [BR:
stow04121
]
Ubiquitin ligases (E3)
HECT type E3
125433778 (ITCH)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
125433778
NCBI-ProteinID:
XP_048354552
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Position
LG05:103331912..103393292
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AA seq
877 aa
AA seq
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MSGNGSRSESVSGLTMKSQLQVTVISAKLKDNKNKWFGPSPYVEVSVDGQSKKTEKCNNT
NSPKWKQHLTVIVTPFSKLSFRVWSHQTLKSDILLGSATLDVHETLKANNMKFEEVIVNL
LLVGDKEPVEVIGDLSVCLDGMQVDPELLTNGDTSSVRSPTQNDGSRAKNEARNSVHNSE
NAEIPGSNESRIANSSDCPLVANGGFKPSRPPRPSRPPPPTPRRPSAPAVCTNGPSPSST
EPEGASTGLVPTSTASAGAEQNFEGTASGAAVPTSAALTTPPISRQVQPVTPTSQSHHAV
PQGPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRT
TTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDFTQSKEFDPLGPLPHGWEK
RTDCNGRVYFVNHNTRITQWEDPRNQGQLNDKPLPEGWEMRFTVDGIPYFVDHNRRTTTY
IDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVSRKTLFEDSFQQIM
SLSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINP
ASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYN
SLIWVKENNIEECGLEMYFSVDKELLGEIKSHDLKPNGSNILVTEENKEEYIRLVAEWRL
SRGVEEQTQAFFEGFNEILPQTYLQYFDAKELEVLLCGMQEIDLTDWQRHAIYRHYTRTS
KQIVWFWQFVKDIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLP
RSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2634 nt
NT seq
+upstream
nt +downstream
nt
atgtctggtaatgggtcaagatcagagtctgtcagtggactaactatgaaatcacaactt
caggttactgttatttctgcaaagttgaaagacaacaaaaacaaatggtttggacctagt
ccttatgtggaagtatcagtagatggacagtcaaagaagacagaaaaatgcaacaataca
aatagtccaaaatggaaacagcatcttacagtaattgttactccatttagcaaactaagc
tttcgcgtatggagtcaccaaacgttgaagtctgatatcttattgggaagtgccactcta
gatgttcatgagacgctcaaagccaacaatatgaagtttgaagaagtaatcgtgaacttg
cttcttgttggtgacaaagaaccagttgaagtgattggagacttgtctgtctgtttagat
ggcatgcaagtagatcctgagctgctaactaatggagatacttcaagtgtaagaagcccc
acgcagaatgatggctccagagcaaaaaatgaggcaaggaatagcgtacataattctgaa
aacgctgagatccccgggtctaatgaaagcaggatagctaatagcagtgattgtcctttg
gttgcaaatggaggttttaagccttctagacctcccagaccttctcgaccacctccaccc
actccacgaaggccctctgctccagctgtatgtaccaatggcccatcaccttcatccaca
gaaccagaaggggccagtacaggattggtgccaacttcaactgcaagtgctggagcggaa
caaaactttgaagggacagcatcaggagcagctgtacccacatcagctgctttgaccaca
ccaccaatatccagacaagttcagccagtaactcctacatcgcagtcacatcatgcagtc
cctcaaggtcctcttccacctggttgggagcaaagagtggaccagcatggtcgagtgtat
tatgttgatcatgttgaaaaaagaactacgtgggacaggccagagccgcttcctccaggc
tgggaacgcagagttgacaacatgggacggatttattatgtggatcactttaccagaacg
acaacatggcagcggccaactttggaatctgtccggaattatgaacaatggcagcttcag
cgcagccaacttcaaggagctatgcagcagtttaatcagagattcatatatgggaatcaa
gacttcacacagagcaaagaattcgatcctcttggtcccttgccgcacggatgggaaaag
agaacagactgcaatggcagagtatattttgtaaatcataatacccgcatcacacagtgg
gaagatcctagaaatcaaggtcagttgaatgacaaacctttaccagagggctgggagatg
agattcactgtggatggaattccatattttgttgatcacaataggagaacaacaacatat
atagatcctcgtactggaaagtctgctctagacaatggacctcagatagcctatgtccgt
gatttcaaagcaaaagtccagtatttccggttttggtgtcagcaattggctatgccccag
cacataaaaatcacagtgagcagaaagacattgtttgaagactcctttcaacagataatg
agtctcagccctcaggatttacgaagacgcttgtgggtcattttccccggagaagaagga
ttagattatggtggtgttgcacgggaatggttctttctgttgtcgcatgaagtgctgaat
ccaatgtattgcctgtttgaatatgcagggaaggataactactgcctacagataaatcct
gcttcttatatcaatccagaccacttgaaatacttccgctttattggcagatttattgcc
atggcattgttccatgggaaatttatagacacaggtttttctctaccattctacaaacgt
atcctcaacaagccagtgggactgaaagatttagaatccatagatccagagttttacaac
tcgctcatctgggtaaaggaaaacaatattgaggaatgtggcctggaaatgtatttctca
gtggataaagaacttctaggtgaaatcaagagccatgatctgaagcccaatggtagtaat
atcttggttaccgaggagaacaaagaagagtacattaggctagtagcagaatggagactt
tcccgaggtgttgaagaacagacccaagctttctttgaaggcttcaatgagattttaccg
cagacgtacttgcagtactttgatgccaaggagctagaggtgcttttgtgtggcatgcag
gagatcgacttaactgactggcaaagacatgccatctaccggcattacaccagaacaagc
aaacagattgtatggttttggcagtttgtgaaggacatagacaatgagaagagaatgaga
ctgctacagtttgttaccggaacatgccgattaccagttggaggatttgctgatctcatg
gggagcaatggaccacaaaagttttgtattgaaaaagttggtaaagaaaactggttgcct
agaagccatacttgtttcaaccgcttggacttgccaccatacaagagttatgaacaactg
aaggagaagcttttgtttgccatagaagaaacagaaggatttggacaagagtaa
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