Sphaerodactylus townsendi (Townsend's least gecko): 125443600
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Entry
125443600 CDS
T08213
Symbol
MLKL
Name
(RefSeq) mixed lineage kinase domain-like protein
KO
K08849
mixed lineage kinase domain-like [EC:
2.7.11.1
]
Organism
stow
Sphaerodactylus townsendi (Townsend's least gecko)
Pathway
stow04217
Necroptosis
stow04623
Cytosolic DNA-sensing pathway
stow05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
stow00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
125443600 (MLKL)
09150 Organismal Systems
09151 Immune system
04623 Cytosolic DNA-sensing pathway
125443600 (MLKL)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
125443600 (MLKL)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
stow01001
]
125443600 (MLKL)
Enzymes [BR:
stow01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
125443600 (MLKL)
Protein kinases [BR:
stow01001
]
Serine/threonine kinases: TKL group
Other
125443600 (MLKL)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MLKL_N
PK_Tyr_Ser-Thr
Pkinase
RPW8
DUF7792
DUF7118
LMBR1
Motif
Other DBs
NCBI-GeneID:
125443600
NCBI-ProteinID:
XP_048371781
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Position
LG14:9638980..9653836
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AA seq
474 aa
AA seq
DB search
MDTVTNILGAAQTIYALFERVKCCKCQSRRLVERVRILMRPIETLQARSTKTVSPQLEEM
LQKLLSVLEKAKNLLVKYSQQNWMQKLLKANECLEEFSSVNEQLSDAAEGLSLLLQVEQT
FKKSFQRDVLRREDSQDFEADRASLEEMHKNSKDTRDGVENIQREVVQLQNKLDKVLQKL
DAGQRSSLADVETVEIEKRLLTKWTLLREFDSHVLYKGEYHKSPVAIKVFKNPVITSTQK
VRELFSKEIKAMKRFESPHILRMYGICIDESGSRPEFSIVTEYCEKGTLREVVRKEPDLP
WKIRLQMALHAAVGVYRLHQTGDKSQLHGSINSNKFLVAEGYNVKLSGFELSQTESSLRR
KHKEKKEKEISPSAYVCPQGLASVNHIYDLPSEIYSFGIVLWEIATSKTPFRGCTSQEIY
QKVCKEGYQEPLGKDCPAGLLEVINLCRSYQPSKRPSAEAIVDALWSISSTTTL
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atggacacggtgacaaatattttgggtgcggcacaaaccatctatgctctgtttgagcgg
gtgaagtgctgtaagtgccaaagccgacgccttgtggagcgcgtccggattctgatgcgg
cccattgagactctgcaggctcgatccaccaagacggtctctccccaactggaagagatg
ctgcagaaactgctgagcgtcctggaaaaggccaagaatctgcttgtgaaatacagccag
cagaactggatgcagaaactcctgaaagccaatgaatgtttggaagagttttcaagcgtg
aatgagcaactcagcgatgctgcggaagggctgtcgttgctactgcaagtggaacagacc
ttcaagaagagttttcagagagatgtcctgcgccgggaggacagccaagactttgaggct
gacagggcatctttggaagagatgcacaaaaacagcaaggacaccagggatggtgtggaa
aacatccagcgtgaagtagtacaacttcagaataaactggacaaagttctgcaaaagttg
gatgcaggacagagaagttccttagcggatgtggaaactgtcgagattgaaaaaagactt
ctcactaagtggactcttttgagggagttcgatagccatgtgctttataaaggagagtat
cacaagtcccccgtggctatcaaagtcttcaaaaacccagtgattaccagcacacagaaa
gtgagagagctcttcagcaaggagatcaaagcgatgaagagatttgaatcgcctcacatc
cttcgtatgtatggcatctgcatagacgagagcggttcaagacctgaattctccattgtc
acagaatattgtgagaaaggcaccttgcgggaggtggtgaggaaagaaccagacttaccc
tggaagattcgcttacaaatggcccttcatgctgctgttggcgtgtacaggttgcaccag
actggggacaagtctcagctgcatggctcaatcaacagcaacaagttcctggtggctgaa
ggctacaatgtcaaactgtcaggctttgaactatctcaaacagaatcatctctccgacgg
aaacacaaggagaaaaaagagaaagaaatctctccttctgcctacgtgtgcccccagggg
ctggcatcagtgaatcacatatatgacttgccaagtgaaatctacagctttggcattgtg
ctttgggagattgcaactagcaagaccccttttagagggtgcacttcacaggagatctat
cagaaagtttgtaaggaaggctaccaagaacccctgggaaaagactgtcctgctggcctg
ctggaggtcatcaacctctgtcggagctaccagccttctaaacgcccatcagctgaagcg
attgtggatgctctctggtccatctcttccactacaaccttgtga
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