KEGG   Winmispira thermophila DSM 6578: Spith_0199
Entry
Spith_0199        CDS       T02016                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
stq  Winmispira thermophila DSM 6578
Pathway
stq00270  Cysteine and methionine metabolism
stq00450  Selenocompound metabolism
stq00670  One carbon pool by folate
stq01100  Metabolic pathways
stq01110  Biosynthesis of secondary metabolites
stq01230  Biosynthesis of amino acids
stq04980  Cobalamin transport and metabolism
stq04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:stq00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Spith_0199
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Spith_0199
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Spith_0199
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Spith_0199
   04980 Cobalamin transport and metabolism
    Spith_0199
Enzymes [BR:stq01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Spith_0199
SSDB
Motif
Pfam: S-methyl_trans Met_synt_B12 Pterin_bind B12-binding B12-binding_2 CdhD
Other DBs
NCBI-ProteinID: AEJ60486
UniProt: G0GCR7
LinkDB
Position
complement(245085..248726)
AA seq 1213 aa
MAHPIEELLKERILILDGAMGTMIQRYHFSEADYRGVLFEKGPTVDGREVALKGNHDLLA
LTRPHVIEEIHRAYLEAGADIIETNTFNATRVSQREYGTEDLVERINLEAARLARRVADE
YSARTPHRPRFVAGVLGPTSKTLSLSPRADDPAFRELSFGELEEDYFGAVRALVEGGADL
ILIETVFDTLNAKAALAAVARFCRESGRAVPVMLSATISDAAGRLLSGQTPRAFLHSVLH
GRPLSVGFNCAFGPEMMRPHLKAIQDAPCAVSVHPNAGLPNALGEYDQGPDQMAATLALY
AREGLLNIAGGCCGTTPDHIRAIAEALEGIPPRPIPSPRPVAVFTGLEVLDQEEAGFILV
GERTNVAGSARFRRLLREERWEEALEVARAQISAGAQMIDVNVDDPLLDPPRFMRRFLSL
AASDPTVARVPVMIDSSDWEVLRAGLESLQGKGVVNSLSLKDGEEVFLERARVVREMGAA
VLVMCFDEEGQAETFERKIAVAQRAYRLLVEEVGIPPWEIVIDPNIFAIGTGMEEHARYG
LDYLEAVRWIKEHLPHARTSGGISNVSFAFRGHEGLRDAIHAVFLHHARAAGLDMAIVNP
QRMMAYEEVPEEVRGLIEDLVFDRRRDATERLLEAARGFSGAGPRVRGEDRAWRDLPVEE
RLAYALKEGIQAYLVEDLEEAHRKAGSALGVIEGPLLTGMEEVGRLFGEGRLFLPQVVRA
ARVMREAVAILEPRLKAEQGGVGKARGVVVLATVKGDVHDIGKNIVKVVLECNGYRVVDL
GVMVPPERVVEAARQGADAVGLSGLITPSLERMRETAEAIDRAGPAVPLLIGGAATSRLH
TALRIAPAYRGPVIHVRDASEAVQVMGRLLSEGREEFVREVRAEQARLREQGVKGRGGVP
GLGEARRRRLRPGPASPVEPRVRGPQVVRMGVAEVRPYLDWRMFYKGWGLPARTPERMRE
AERAEAVRLREEAEGVLARMEGRVRIEGVVGFFPARDVGEDCIGVLGWGGEGVIRRLPML
RQQAVKEGEPTRSLVDFLPHEGHDYLGLFVITAGKDIERFLAEEGPGEPYRELMVRLLAD
RLAEAASEYLHMLVRTTLWGYAPEEHLSPEEVLAGRYRGIRPAPGHAACPDHSLKQDIFE
LLGAEARLEVRLTESFMMVPPSSVAGFYFSHPESRYFAVGRITEEQLRDYARRRERPVDE
VRGWLDHIVVADS
NT seq 3642 nt   +upstreamnt  +downstreamnt
atggcccaccccatagaggagctcctcaaggagcgcatcctcatcctcgacggtgccatg
ggcaccatgatccagcgctaccacttctcggaggccgactaccggggggtcctgttcgag
aaggggcccacggtggacggccgcgaggtcgctctcaaggggaatcacgacctcctcgcg
ctcaccaggccccacgtgatagaggagatccaccgggcctacctcgaggcgggcgccgac
atcatcgagaccaacaccttcaacgccacgagggtctcccagcgcgagtacgggaccgag
gacctggtggagcggatcaacctggaggcggcgcgcctcgcgcgtcgcgtggccgacgag
tactcggcccgtacccctcacaggccgcggttcgtcgcaggggtgctcggccccacgagc
aagaccctctccctctcgccccgggcggacgacccggcctttcgcgagctctcgttcggg
gagctggaggaggactacttcggcgcggtgcgtgccctcgtggagggcggggcggacctc
atcctcattgagacggtgttcgacaccctcaacgccaaggcggccctcgcagcggtcgcg
cggttttgcagggagagcgggcgggcggtgccggtgatgctctcggccaccataagcgat
gcggcgggccgcctcctctcgggccagaccccccgcgccttcctccactcggtgctccac
ggccggccgctctcggtggggttcaactgcgccttcggtcccgagatgatgcgccctcac
ctcaaggccattcaggatgcgccctgcgccgtgagcgtgcatccgaacgcggggctcccc
aatgccctcggcgagtacgaccaggggccggaccagatggccgcaaccctcgccctttac
gcgagggaggggctcctcaacatcgcaggcgggtgctgcggcaccacgccggaccacatc
cgggcgatcgcagaggccctggaggggatccctccccggcccatcccctcccccaggccg
gtggcggtcttcaccgggctggaggtgctcgaccaggaggaggcgggcttcatcctggtg
ggcgagcgcaccaacgtggcgggttctgcgaggttccgccgcctcctccgggaggagcgg
tgggaggaggccctggaggtggcgcgggcgcagatctccgcgggcgcccagatgatcgac
gtgaacgtggacgatccgctcctcgatcccccccgtttcatgcggcgcttcctctccctg
gcggcctcggatcccacggtggcgcgggtgccggtgatgatcgattcctcggactgggag
gtgctgagggcagggctcgagtccctccaggggaagggcgtggtcaactccttgagcctc
aaggacggggaggaggtcttcctcgaacgggcgcgggtggtgcgggagatgggggctgcg
gtcctcgtgatgtgcttcgacgaggagggacaggccgagaccttcgagcgcaagatcgcc
gtggcgcagcgggcctaccggctcctggtggaggaggtggggatcccgccgtgggagatc
gtgatcgatccgaacatcttcgccatcgggacggggatggaggagcacgcccgctacggc
ctcgactacctggaggcggtgcgctggatcaaggagcatctcccccacgcgcgcacctcg
ggtgggatcagcaatgtctcgttcgccttcagggggcacgagggcctcagggatgcgatc
cacgcggtcttcctccaccacgcgagggcggcggggctcgatatggcgatcgtgaatccc
cagcggatgatggcctacgaggaggtgccggaggaggtgcgggggctgatcgaggatctg
gtcttcgaccggcggagggatgcgacggagcgtctcctcgaggcggcccgggggttttcc
ggcgccgggccgagggtgcggggcgaggatcgggcgtggagagacctgccggtggaggag
cggctcgcctacgccctgaaggaggggatccaggcgtacctcgtggaggatctggaggag
gcgcaccggaaggcggggagcgcgctgggggtgatcgaggggccgctccttacggggatg
gaggaggtggggaggctcttcggcgaggggaggctgttcctgccgcaggtggtgagggcg
gcgcgggtgatgagggaggcggtggcgatcctggagccgaggctcaaggcggagcaggga
ggggtcgggaaggcgaggggggtggtggtgctcgccacggtgaagggggatgtccacgat
atcgggaagaacatcgtgaaggtggtgctcgagtgcaacgggtaccgtgtggtggacctg
ggggtgatggtgccgcccgagagggtggtggaggcggcgcggcagggggccgatgcggtg
gggctgtcggggctcatcacgccgtcgctcgagcggatgcgggagacggccgaggcgatc
gatcgggcggggccggcggtgccgctcctcataggtggggcggcgacgagcagactccac
acggcgctcaggatcgccccggcctaccgggggccggtgatccacgtgcgggatgcctcg
gaggcggtgcaggtgatggggcggctcctctcggaggggcgggaggagttcgtccgggag
gtgagggcggagcaggcgcggctgagggagcagggggtgaaggggagagggggcgtgccg
gggctgggggaggcgcggcggaggaggctgcggcctgggccggcttcgccggtcgagccg
cgggtgcgggggcctcaggtggtgcggatgggggtggccgaggtgcgcccctacctggac
tggcggatgttctacaaggggtgggggctccctgcgcgcacgcccgagcggatgcgggag
gcggagcgggcggaggcggtgcggctgcgggaggaggcggagggggtgctcgcgcggatg
gaggggagggtgcggatcgagggggtggtggggttcttcccggcgcgggatgtgggggag
gactgcatcggggtgctggggtgggggggagagggggtgatccggcggctgcccatgcta
cggcagcaggcggtgaaggaaggggagcccacccggtccctcgtggatttcctgcctcac
gaagggcatgactacctcggcctcttcgtcattaccgcaggcaaggacatagagcgcttc
ctcgcagaggaggggcctggagaaccctatcgcgagctcatggtacggctcctcgccgac
agactcgccgaggcggcgagcgagtacctccacatgctcgtgcgcaccaccctctggggc
tatgcccctgaggaacacctctcccccgaggaggtgctcgcaggcaggtaccggggcatc
cgacctgcacccggacacgccgcctgccccgaccacagcctcaaacaggacatcttcgag
ctcctcggggcagaggcacgcctggaggtcaggctcaccgagtcgttcatgatggtcccc
ccatcctcggtcgcgggcttctacttctcgcatcccgagagccgctatttcgccgtggga
cgcatcaccgaggaacaactccgcgactatgcacgccgcagggaaaggcctgttgacgaa
gtgcgaggctggctcgaccacatcgtggtcgcagattcatga

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