Streptomyces sp. CNQ-509: AA958_32215
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Entry
AA958_32215 CDS
T03968
Name
(GenBank) squalene-hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
strc
Streptomyces sp. CNQ-509
Pathway
strc00909
Sesquiterpenoid and triterpenoid biosynthesis
strc01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
strc00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
AA958_32215
Enzymes [BR:
strc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
AA958_32215
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
AA958_32215
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
AKH86116
UniProt:
A0A0F7ND16
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Position
7582865..7584898
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AA seq
677 aa
AA seq
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MKATADGGNANDTAPAGAAASLLAARQAVERASANLLGRQDVEGWWKGDLETNVTMDAED
LFLREFLGVRDEHTTRAAARFIRGRQGAEGAWATFHGGPGDISATVEAYVALRLAGDAPD
EEHMAQAAAWVRAHGGIAATRVFTRIWLALFGWWRWEDLPELPPELIYLPSWFPLNIYDF
GCWARQTIVPLTVVSAKRPVHPAPFALDELHTDPAVPNPPRRQAPATSWDGLFQRLDRAL
HVYRKVAVRPLRKAALRSCARWIIERQESDGCWGGIQPPAVYSVIALNLLGYDLDHPVLK
AGLESLDRFAVWTDAAEKPAADTGAASDTGDTRDDGPVRMIEACQSPVWDTCLATIALVD
AGVPADHPQLVKAADWMLAEQVLATGDWSVRRPGLTPGGWAFEFHNDNYPDTDDTAEVVL
ALRRVAHPDQARVDAAVERAVRWLAGMQSKNGAWGAFDADNTSALPNKLPFCDFGEVIDP
PSADVTAHVVEMLAGEKLGDDPHARRGVAWLLAEQEAAGGWFGRWGVNYVYGTGSAVPAL
VAAGLPTSHPAIRRAVSWLESVQNEDGGWGEDLRSYPDPQWIARGDSTASQTGWALLALL
AAGEHDSAAVERGVAWLVRTQLPDGSWDEPQFTGTGFPWDFSINYHLYRMVFPLTALGRY
LSATAGLTPAAGDGREV
NT seq
2034 nt
NT seq
+upstream
nt +downstream
nt
atgaaagccactgccgatggcggcaacgcaaacgacaccgcccccgcgggggcggcggct
tccttactggccgcgaggcaggccgtcgagcgggccagcgccaacctgctcggccggcag
gacgtcgaaggctggtggaagggcgacctggagaccaacgtcaccatggacgccgaggat
ctgttcctccgcgagttcctgggcgtacgggacgagcacaccacccgcgccgccgcccgc
ttcatccgcggccggcagggcgcggagggcgcctgggcgacgttccacggcggccccggg
gacatctccgcgaccgtggaggcgtacgtcgcgctgcggctcgccggcgacgcgcccgac
gaggagcacatggcgcaggccgccgcctgggtgcgcgcgcacggcggcatcgccgccacc
cgcgtcttcacccgcatctggctggcgctcttcggctggtggcgctgggaggacctgccc
gagctgccgcccgagctgatctacctgccgtcctggttcccgctgaacatctacgacttc
ggctgctgggcccggcagacgatcgtgccgctgaccgtcgtctccgccaagcgcccggtg
caccccgccccgttcgccctcgacgagttgcacaccgaccccgccgtgcccaacccgccc
cggcggcaggcgccggcgacgagctgggacggcctcttccagcggctggaccgggcgctg
cacgtgtaccgcaaggtcgccgtgcgcccgctgcgcaaggcggcgctgcgcagttgcgcc
cgctggatcatcgagcgccaggagagcgacggctgctggggcggcatccagccgcccgcc
gtctactcggtgatcgcgctgaacctgctcggctacgacctggaccacccggtgctgaag
gccgggctcgagtccctggaccgcttcgcggtctggaccgacgccgcggagaagcccgcg
gccgacaccggcgccgcgagtgacacgggagacacgcgcgacgacggcccggtccggatg
atcgaggcgtgccagtccccggtctgggacacctgcctggcgaccatcgcgctcgtcgac
gccggcgtgcccgccgaccacccccagctcgtcaaggccgccgactggatgctggcggaa
caggtgctggccaccggcgactggtcggtacgccgcccgggactcacccccggcggctgg
gcgttcgagttccacaacgacaactaccccgacaccgacgacaccgcggaggtcgtcctg
gccctgcgccgcgtcgcccaccccgaccaggcgcgcgtcgacgccgccgtggagcgcgcc
gtgcgctggcttgcgggcatgcagtcgaagaacggcgcctggggcgcgttcgacgcggac
aacacctcggcgctccccaacaagctgccgttctgcgacttcggcgaggtcatcgacccg
ccgtcggccgacgtcacggcgcacgtcgtggagatgctcgccggcgagaagctcggcgac
gacccgcacgcccgccgcggcgtggcctggctgctcgccgagcaggaggcggccggcggc
tggttcggccgctggggcgtcaactacgtgtacggcacgggctccgcggtgcccgcgctg
gtcgccgccgggctgcccacgtcgcacccggcgatccggcgggccgtctcgtggctggag
agcgtgcagaacgaggacggcggctggggcgaggatctgcgctcgtacccggacccgcag
tggatcgcccgcggcgactccaccgcctcgcagaccgggtgggcactgctcgcgctgctg
gccgcgggcgagcacgacagcgcggcggtggagcgcggcgtcgcctggctggtccgcacc
caactgcccgacgggtcctgggacgagccgcagttcaccggcaccggcttcccgtgggac
ttctccatcaactaccacctgtaccggatggtcttcccgctcaccgcgctcggccgctat
ctgtccgcgaccgccggcctgacaccggccgccggtgacggccgggaggtctga
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