KEGG   Streptomyces sp. CCM_MD2014: NI25_30905
Entry
NI25_30905        CDS       T04862                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
strd  Streptomyces sp. CCM_MD2014
Pathway
strd00270  Cysteine and methionine metabolism
strd00450  Selenocompound metabolism
strd00670  One carbon pool by folate
strd01100  Metabolic pathways
strd01110  Biosynthesis of secondary metabolites
strd01230  Biosynthesis of amino acids
strd04980  Cobalamin transport and metabolism
strd04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:strd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    NI25_30905
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    NI25_30905
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    NI25_30905
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    NI25_30905
   04980 Cobalamin transport and metabolism
    NI25_30905
Enzymes [BR:strd01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     NI25_30905
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: AIV37372
UniProt: A0A0N6ZQM8
LinkDB
Position
6964071..6967583
AA seq 1170 aa
MASSPSTPPADTRTRVSALREALATRVVVADGAMGTMLQAQNPTLDDFQQLEGCNEVLNV
TRPDIVRSVHEEYFAAGVDCVGTNTFGANHSALGEYDIPERVQELSEAGARVAREVADEF
AARDGRQRWVLGSIGPGTKLPTLGHAPYTVLRDAYQRNAEGLVAGGADALLVETTQDLLQ
TKASVLGARRALDALGLDLPVIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGMNCAT
GPAEMSEHLRYLARHARIPLTCMPNAGLPVLGKDGAHYPLTAPELADAHETFVREYGLSL
VGGCCGTTPEHLRQVVERVRGSEPTERHPRPEPGAASLYQTVPFRQDTSYLAIGERTNAN
GSKKFREAMLEGRWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTL
PIVLDSTEVDVIRAGLEKLGGRAVINSVNYEDGAGPESRFARVTRLAREHGAALIALTID
EEGQARTAEKKVEIAERLIDDLTGNWGIRESDILVDCLTFTICTGQEESRKDGLATIEGI
RELKKRHPDVQTTLGLSNISFGLNPAARILLNSVFLDECVKAGLDSAIVHASKILPIARF
DEEQVTTALDLIYDRRREGYDPLQKLMQLFEGATAKSLKASKAEELAALPLEERLKRRII
DGEKNGLEQDLDDALRERPALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAV
AHLEPHMEKTDDDGKGTIVLATVRGDVHDIGKNLVDIILSNNGYTVVNLGIKQPVSAILE
AADEHKADVIGMSGLLVKSTVIMKENLEELNQRGLAADYPVILGGAALTRAYVEQDLHEV
YDGEVRYARDAFEGLRLMDALIGIKRGVPGAKLPELKQRRVRAATVEIEDRPEEGSVRSD
VATDNPVPEPPFRGTRVVKGIQLKEYASWLDEGALFKGQWGLKQARTGEGPSYEELVESE
GRPRLRGLLDRLQTENLLEAAVVYGYFPCVSKDDDLIVLDDDGNERTRFTFPRQRRGRRL
CLADFFRPEESGEVDVVGFQVVTVGSRIGEETARMFEANAYRDYLELHGLSVQLAEALAE
YWHARVRSELGFAGEDPADMEDMFALKYRGARFSLGYGACPDLEDRAKIAALLEPERIGV
HLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggcctcgtcgccatccaccccgcccgccgacacccgcacccgcgtgtccgccctccga
gaggccctcgccacccgtgtggtggtcgccgacggcgccatgggcaccatgctccaggcc
cagaaccccacgctggacgacttccagcagctggaggggtgcaacgaggtcctgaacgtg
acccggccggacatcgtgcgctcggtgcacgaggagtacttcgcggccggcgtcgactgc
gtcggcacgaacaccttcggcgccaaccactccgccctcggcgagtacgacatccccgag
cgcgtccaggaactgtccgaggccggcgcccgcgtcgcccgcgaggtcgcggacgaattc
gcggccagggacggacggcagcgctgggtcctgggctccatcgggcccggcaccaagctc
cccaccctgggccacgccccctacaccgtgctgcgcgacgcctatcagcgcaacgccgag
ggcctggtcgccggcggcgccgacgccctgctcgtggagaccacccaggacctgctgcag
accaaggcctccgtgctcggcgcccggcgcgccctcgacgccctcggcctcgacctgccc
gtcatcgtctccgtcaccgtcgagaccaccggcaccatgctcctcggctccgagatcggc
gccgcgctcaccgcgctggagccgctcggcatcgacatgatcggcatgaactgcgcgacc
ggcccggcggagatgagcgagcacctgcgctacctcgcccgtcacgcccggatcccgctg
acctgcatgcccaacgccggtctgcccgtcctcggcaaggacggcgcccactacccgctg
accgcgcccgagctggccgacgcccacgagaccttcgtccgcgaatacggcctgtcgctg
gtcggcggctgctgcggcaccacccccgagcacctgcgccaggtcgtcgagcgggtccgc
ggcagcgaacccaccgagcgccacccgcgcccggagcccggcgccgcctccctctaccag
accgtgcccttccgccaggacacctcgtacctggccatcggggagcgcacgaacgccaac
ggctccaagaagttccgcgaggccatgctggagggccgctgggacgactgtgtggagatg
gcccgggaccagatccgcgagggcgcgcacatgctcgacctgtgcgtggactacgtcggc
cgggacggcgtcgccgacatggaggagctggccggccggttcgccaccgcctcgacgctg
ccgatcgtgctggactccaccgaggtcgacgtgatccgggcgggtctggagaagctcggc
ggccgcgcggtgatcaactccgtgaactacgaggacggtgccggacccgagtcccgcttc
gcccgcgtcacccggctggcccgggagcacggggccgcgctgatcgcgctgaccatcgac
gaggagggccaggcccgcaccgccgagaagaaggtcgagatcgccgaacggctcatcgac
gacctcaccggcaactggggcatccgtgagtccgacatcctcgtcgactgcctgaccttc
acgatctgcaccggtcaggaggagtcccgcaaggacggcctggccaccatcgagggcatc
cgggagctgaagaagcgccacccggacgtgcagaccacgctcggcctgtcgaacatctcc
ttcggcctcaacccggccgcccgcatcctgctgaactccgtcttcctcgacgagtgcgtg
aaggcgggcctggactcggcgatcgtgcacgcgtcgaagatccttccgatcgcccgtttc
gacgaggagcaggtcaccaccgccctcgacctcatctacgaccgccgccgcgagggctac
gacccgctccagaagctcatgcagctcttcgagggcgccacggccaagtccctgaaggcg
tccaaggccgaggaactggccgccctcccgctggaggagcgcctcaagcgccgcatcatc
gacggcgagaagaacggcctcgaacaggacctggacgacgccctccgggagcgtccggcg
ctcgacatcgtcaacgacacgctgctcgacggcatgaaggtcgtcggcgaactgttcggc
tccggccagatgcagctgccgttcgtgctccagtccgccgaggtcatgaagaccgcggtg
gcccacctggagccgcacatggagaagaccgacgacgacggcaagggcaccatcgtgctg
gccacggtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctgtcc
aacaacggctacaccgtcgtcaacctcggcatcaagcagcccgtgtccgcgatcctggag
gcggccgacgagcacaaggccgacgtcatcggcatgtccggcctcctggtcaagtccacg
gtgatcatgaaggagaacctggaggagctcaaccagcgggggctggccgccgactacccg
gtcatcctcggcggcgccgccctcaccagggcctacgtcgaacaggacctgcacgaggtc
tacgacggcgaggtccgctacgcccgcgacgccttcgagggcctgcgcctgatggacgcc
ctgatcggcatcaagcgcggcgttcccggcgccaagctgcccgagctgaagcagcgccgg
gtgcgggcggccacggtcgagatcgaggaccgtccggaagagggcagcgtccgctccgac
gtcgccaccgacaaccccgtgcccgagccgccgttccgcggcacccgcgtggtcaagggc
atccagctcaaggagtacgcgtcctggctcgacgagggcgcgctcttcaagggccagtgg
ggtctcaagcaggcccgcaccggcgaggggccctcctacgaggaactcgtcgagagcgag
ggccggccccggctgcgggggctgctggaccggctccagacggagaacctgctggaggcg
gccgtggtctacggctacttcccctgcgtgtccaaggacgacgacctgatcgtcctggac
gacgacggcaacgagcgcacccgcttcaccttcccgcgccagcgccgcggccggcgcctg
tgcctggccgacttcttccgcccggaggagtccggcgaggtcgacgtggtcggtttccag
gtcgtcaccgtcggctcccgcatcggcgaggagacggcccggatgttcgaggccaacgcc
taccgggactacctcgagctgcacggactgtccgtccagctcgccgaggccctcgccgag
tactggcacgcacgcgtgcgctccgaactgggcttcgccggggaggacccggccgacatg
gaggacatgttcgccctgaagtaccggggggcccgcttctccctcggctacggcgcctgc
cccgacctggaggaccgcgccaagatcgccgccctcctcgagcccgagcgcatcggcgtc
cacctctccgaggagttccagctccaccccgagcagtccaccgacgccatcgtcatccac
cacccggaggcgaagtacttcaacgcccgctag

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