Streptomyces sp. 769: GZL_03424
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Entry
GZL_03424 CDS
T03587
Name
(GenBank) 2-oxoglutarate dehydrogenase C E1 subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
stre
Streptomyces sp. 769
Pathway
stre00020
Citrate cycle (TCA cycle)
stre00630
Glyoxylate and dicarboxylate metabolism
stre00785
Lipoic acid metabolism
stre01100
Metabolic pathways
stre01110
Biosynthesis of secondary metabolites
stre01120
Microbial metabolism in diverse environments
stre01200
Carbon metabolism
stre01210
2-Oxocarboxylic acid metabolism
Module
stre_M00009
Citrate cycle (TCA cycle, Krebs cycle)
stre_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
stre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
GZL_03424
00630 Glyoxylate and dicarboxylate metabolism
GZL_03424
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
GZL_03424
Enzymes [BR:
stre01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
GZL_03424
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
GZL_03424
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
GZL_03424
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
GZL_03424
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AJC56010
UniProt:
A0A0A8EIK1
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All DBs
Position
3671139..3674903
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AA seq
1254 aa
AA seq
DB search
MSLQSPNSASVSTEQGAQGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GDATAPAKPAQGSAPAPAPSAPAPAAAPKPAAAPAAKPVAAAPVAPVAPAKAAPAKPAAK
PASAATQPAEAPEGPELVTLRGPSAAVAKNMSASLELPTATSVRAVPVKLLFDNRIVINN
HLKRARGGKVSFTHIIGYAMVQALKAMPSMNNSFAEKDGKPTLVKPPHINLGLAIDLVKA
KGERQLVVAAIKKAETMTFFEFWQAYEDIVRRARDNKLTMADFTGVTASLTNPGGIGTVH
SVPRLMPGQSMIMGVGSMDYPAEFQGTSQDALNKLGVSKVMTLTSTYDHRVIQGAASGEF
LRIMSQLLLGENDFFDDIFKSLRIPYEPIRWLRDIDASHDDDVTKAARVFELIHSYRVRG
HVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMKLRDILGVLRDSYC
RTTGIEFMHIQDPKQRKWIQDRVERTHKSPERDEQLRILRRLNSAEAFETFLQTKYVGQK
RFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGN
LDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLTANPSHLEAVDPVVEGVSRAKQDIIN
KGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESS
RSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNE
SDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVRD
ATTAPVTPEVPQPKAEFPVFVDTAISQEVVKRIAESQVNIPDHITVHPRLLPQLQRRAAM
IEDDTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHAVLIDRKTGEDYTPLLYL
SDDQARFNVYDSLLSEYAAMGFEYGYSLARPESLVMWEAQFGDFANGAQTVIDEFISSAE
QKWGQTSGVTLLLPHGYEGQGPDHSSARIERYLQLCAQNNMTVAMPTLPSNYFHLLRWQV
HNPHHKPLIVFTPKSMLRLKAAASKTAEFTTGGFRPVIGDSTVKAEDVRKVVFCSGKVYY
DLEAEREKRGAFDTALVRIERLYPLPGAELQAEIKKFPNAGKYLWAQEEPANQGAWPFLG
LNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQAQLMAEVFDA
NT seq
3765 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacagtgcgagtgtctcgaccgaacagggagcgcaggggaag
aatcctgccgccgcgttcgggcccaacgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggcgatgccaccgcgccggccaagcccgcgcagggctcggcccccgccccggctccgtcg
gcgccggcccccgcggccgcaccgaagcccgccgccgcccccgcggccaagcccgtcgcg
gctgcgccggtcgcgccggtcgcgccggccaaggctgcccccgcgaagcccgcggcgaag
ccggcgtcggccgccacgcagcccgccgaggcccccgagggtccggagctcgtgacgctg
cgcggcccgtcggcggccgtggcgaagaacatgagcgcgtccctggagctgccgacggcc
acgtccgtccgcgcggtcccggtgaagctgctgttcgacaaccggatcgtcatcaacaac
cacctcaagcgcgcccgcggcgggaaggtctccttcacgcacatcatcgggtacgccatg
gtgcaggccctcaaggccatgccgtcgatgaacaactccttcgcggagaaggacggcaag
ccgacgctggtcaagcccccgcacatcaacctcggcctggcgatcgacctggtcaaggcg
aagggcgagcgccagctggtcgtcgcggccatcaagaaggccgagacgatgaccttcttc
gagttctggcaggcgtacgaggacatcgtccgccgggcccgtgacaacaagctcacgatg
gccgacttcaccggggtcaccgcgtcgctgacgaaccccggcggcatcggcaccgtccac
tcggtgccccgtctgatgcccggccagtccatgatcatgggcgtcggctcgatggactac
ccggccgagttccagggcacctcgcaggacgccctgaacaagctgggcgtctccaaggtc
atgacgctgaccagcacctacgaccaccgggtgatccagggcgccgcctccggcgagttc
ctgcggatcatgagccagctgctgctcggcgagaacgatttcttcgacgacatcttcaag
tcgctgcggatcccctacgagccgatccgctggctgcgcgacatcgacgcctcgcacgac
gacgacgtcaccaaggccgcccgggtcttcgagctgatccactcctaccgggtccgcggc
cacgtcatggccgacaccgacccgctggagtaccaccagcgcaagcaccccgacctggac
atcaccgagcacggcctcaccctgtgggacctggagcgggagttcgcggtcggcggcttc
gccggcaagtccatgatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgc
cgcaccaccggcatcgagttcatgcacatccaggaccccaagcagcgcaagtggatccag
gatcgggtcgagcgcacgcacaagtcgcccgagcgcgacgagcagctgcgcatcctgcgc
cggctgaactccgccgaggcgttcgagaccttcctgcagaccaagtacgtcggccagaag
cggttctcgctggagggcggcgaatcggtcatcccgctgctggacgcggtcatcgactcc
gcggccgaggcgcggctggacgaggtcgtcatcggcatggcccaccgcggccgcctcaac
gtcctcgccaacatcgtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaac
ctcgacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggc
accttcaccggcctggacggcgagcagatcaaggtctcgctgaccgccaacccctcccac
ctggaggccgtggacccggtcgtcgagggtgtctcccgcgccaagcaggacatcatcaac
aagggcggcacggacttcaccgtcctgccgatccagctgcacggcgacgcggcgttcgcc
ggccagggcgtggtcgccgagacgctgaacatgtcgcagctgcgcggctaccgcaccggc
ggcacggtccacgtcgtcatcaacaaccaggtcggcttcaccgcggcccccgagtcctcg
cgttcctccatgtacgcgacggacgtggcccgcatgatcgaggccccgatcttccacgtc
aacggcgacgaccccgaggccgtcgtccgcgtcgcgcggctcgccttcgagttccgccag
gcgttcaacaaggacgtggtcatcgacctgatctgctaccgccgccgcggccacaacgag
tcggacaacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgctcg
gtgcgcaagctctacaccgagtcgctgatcggccggggcgacatcaccctcgaagaggcc
gagcaggcgctgcaggacttccagggccagctggagaaggtcttcaccgaggtccgcgac
gccacgacggccccggtcacccccgaggtgccgcagcccaaggccgagttcccggtcttc
gtggacaccgcgatctcccaggaggtcgtcaagcggatcgccgagtcccaggtcaacatc
cccgaccacatcaccgtccacccgcgtctgctgccgcagctgcagcgccgggcggcgatg
atcgaggacgacaccatcgactggggcatgggcgagaccctggccatcggctcgctgctg
atggagggcaccccggtccggctcgccggccaggactcccgccgcggcacgttcggccag
cgccacgcggtgctgatcgaccggaagaccggcgaggactacaccccgctgctgtacctg
tccgacgaccaggcccgcttcaacgtctacgactcgctgctcagcgagtacgcggcgatg
ggcttcgagtacggctactcgctggcgcgtccggagtcgctggtcatgtgggaggcgcag
ttcggcgacttcgccaacggcgcgcagaccgtcatcgacgagttcatctcctcggcggag
cagaagtggggccagacctccggcgtcaccctgctgctcccgcacggctacgagggccag
ggcccggaccactcctcggcccggatcgagcgctacctccagctgtgcgcgcagaacaac
atgaccgtcgcgatgccgacgctcccgtcgaactacttccacctgctgcgctggcaggtg
cacaacccgcaccacaagccgctgatcgtcttcaccccgaagtcgatgctgcgtctgaag
gcggcggcgtcgaagacggcggagttcaccaccggcggcttccgtccggtcatcggcgac
agcacggtcaaggccgaggacgtccgcaaggtcgtcttctgctccggcaaggtctactac
gacctggaggccgagcgggagaagcgcggcgccttcgacaccgcgctggtccgcatcgag
cggctgtacccgctgccgggtgccgagctccaggcggagatcaagaagttcccgaacgcc
gggaagtacctgtgggcgcaggaggagccggcgaaccagggtgcctggccgttcctcggt
ctcaacctgatcgaccacctggacctggcggtcggcgccgacgtcccgcacggtgagcgc
ctgcgccgcatctcgcggccgcacggctcgtcgccggcggtcggctccgccaagcggcac
caggccgagcaggcccagctcatggcggaggtcttcgacgcctga
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