Streptomyces sp. 769: GZL_06337
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Entry
GZL_06337 CDS
T03587
Name
(GenBank) 2-oxoacid dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stre
Streptomyces sp. 769
Pathway
stre00010
Glycolysis / Gluconeogenesis
stre00020
Citrate cycle (TCA cycle)
stre00620
Pyruvate metabolism
stre00785
Lipoic acid metabolism
stre01100
Metabolic pathways
stre01110
Biosynthesis of secondary metabolites
stre01120
Microbial metabolism in diverse environments
stre01200
Carbon metabolism
stre01210
2-Oxocarboxylic acid metabolism
Module
stre_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
GZL_06337
00020 Citrate cycle (TCA cycle)
GZL_06337
00620 Pyruvate metabolism
GZL_06337
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
GZL_06337
Enzymes [BR:
stre01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
GZL_06337
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AJC58907
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Position
complement(6819796..6822471)
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AA seq
891 aa
AA seq
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MPDPVRLPYSQLDQLPDRDPEETAEWRESLDAVTKAAGPHRAAYLMRRALEHTAHTEGTD
LPSLVETDYVNTIPTSAEPAFPGDEAMEARITAWNRWNAAAMVTRGSKLGLGGHIATFAS
AAWLYETGFQHFFRGKEGDGSGDQLYIQGHASPGVYARAFLEGRLTEDQLDHFRQEAGGE
GLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLEHRGIKDTGNSHVWAFLGDGE
MDEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRPNFKIVQELEAQFRAAGWNVVKA
LWGQAWDEIFALDTDGALIQRLRETPDAQFQTYATRDAAYLREHFFGASDTLKAIGARLS
DAKLLELFQTSRAGHEPRKVYAAYRAAVEHKGAPTVILAQTVKGYTLGTGFESRNANHQM
KKLTMAEFRTMRDLLELPIPDSALEGDLVPYWRPAEDSPEMQYLRTRRAALDGPAPARKV
VAKPLPMPADKAFDALKKGSGSQEIATTMAFVRLVKDLMRDKETGKRWVPIVPDEARTFG
MESLFPTAGLYSPKGATYDPVDRDQLLWYKEARNGQILNEGITEAGSLADFTAAATSYAT
HGEPMIPFYIFYSMFGWQRTADQFWALADQLGRGFVIGATAGRTTMTGEGLQHADGHSHL
IASTNPAALSYDPAFAYEVAVIVKEGLRRMYGPDAEDVFYYLTVYNETKVQPAMPEGVEE
GILKGLYRFKEATSIEGAEVPRLQLLASGTAIHWALEAQALLAADWGVAADVWSAPSWTE
LRRDALECDAARLEGEDRIPYVTRALAGAPGPVVAVSDWMRAVPDQIAPWVEQDWTSIGT
DGFGLSDTREAARRYFGVDPQSVVVQALAALARRGDVKPESVKEARERYGL
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atgcccgatcccgtgcgcctgccgtacagccagctcgaccagctcccggaccgcgatccc
gaggagacggccgaatggcgcgagtcgctggacgccgtcaccaaggcagcgggcccgcat
cgcgccgcgtacctgatgcgccgcgccctggagcacaccgcgcacaccgaaggcaccgac
ctgccctcgctggtggagacggactacgtcaacaccatcccgacctccgccgagcccgcg
ttcccgggtgacgaggcgatggaggcccggatcaccgcctggaaccgctggaacgccgcc
gccatggtgacccgcggctccaagctcggcctgggcggccacatcgccaccttcgcctcg
gccgcctggctgtacgagaccggcttccagcacttcttccgcggcaaggaaggcgacggc
agcggcgaccagctctacatccagggccacgcctcccccggcgtctacgcccgcgccttc
ctcgaaggccggctcaccgaggaccagctcgaccacttccgccaggaggccggcggcgag
ggcctgccctcctacccgcacccgcggcggctgccctggctgtgggagttccccaccgtc
tccatgggcctcggcccgctctcggcgatctaccaggcgcgcttcaaccgctacctggag
caccgcggcatcaaggacaccggcaactcgcacgtctgggccttcctgggcgacggcgag
atggacgagccggagtcgaccgccgcactggcgctggccggccgcgagggcctggacaac
ctgaccttcgtcatcaactgcaacctgcagcgcctggacggcccggtccgccccaacttc
aagatcgtgcaggagctggaggcccagttccgtgccgccggctggaacgtcgtcaaggcc
ctgtggggccaggcgtgggacgagatcttcgcgctcgacaccgacggcgcgctgatccag
cgcctccgtgagaccccggacgcgcagttccagacgtacgccacccgcgacgccgcctac
ctgcgcgagcacttcttcggcgcgagcgacaccctcaaggcgatcggcgcgcggctctcc
gacgccaagctgctggagctgttccagacgtcccgcgccggccacgagccgcgcaaggtg
tacgccgcgtaccgggccgccgtcgagcacaagggcgcgccgacggtcatcctggcgcag
accgtcaagggctacaccctgggcacgggcttcgagtcccgcaacgccaaccaccagatg
aagaagctgacgatggcggagttccgcaccatgcgggacctgctcgaactccccatcccg
gacagcgccctggagggcgacctggtgccgtactggcgcccggccgaggactccccggag
atgcagtacctgcgcacccggcgcgccgccctggacggcccggccccggcccgcaaggtc
gtggccaagccgctgccgatgcccgcggacaaggcgttcgacgcgctgaagaagggctcg
ggcagccaggagatcgccaccaccatggcgttcgtccggctggtcaaggacctgatgcgg
gacaaggagaccggcaagcgctgggtcccgatcgtcccggacgaggcccgcaccttcggc
atggagtcgctcttcccgaccgccggcctctactcccccaagggcgcgacctacgacccg
gtcgaccgggaccagctgctctggtacaaggaggccaggaacggccagatcctcaacgag
gggatcaccgaggccggttcgctggccgacttcaccgccgccgcgacgtcgtacgcgacg
cacggcgagccgatgatccccttctacatcttctactcgatgttcggctggcagcgcacc
gccgaccagttctgggcgctcgccgaccagctgggccgcggcttcgtgatcggcgccacc
gccggccgcacgacgatgaccggtgagggcctccagcacgccgacggccactcgcacctg
atcgcctcgaccaacccggcggcgctctcgtacgacccggcgttcgcctacgaggtcgcg
gtgatcgtcaaggagggtctgcgccggatgtacggcccggacgcagaggacgtcttctac
tacctgacggtctacaacgagaccaaggtgcaaccggcgatgccggagggcgtcgaggag
ggcatcctcaagggcctctaccgcttcaaggaggccacgtccatcgagggcgccgaggtc
ccgcggctccagctgctggcctccggcaccgcgatccactgggccctggaggcacaggcg
ctgctggccgccgactggggcgtggcggcggacgtgtggtccgctccgtcctggacggag
ctccgccgcgacgccctggagtgcgacgcggcccgcctggagggcgaggaccggatcccc
tacgtcacccgtgcactggccggcgcccccggtccggtcgtcgcggtgagcgactggatg
cgggcggtcccggaccagatcgccccgtgggtcgagcaggactggacgtccatagggacg
gacggcttcggcctgtccgacacccgcgaggcggcccgccggtacttcggcgtcgacccg
cagtcggtggtcgtccaggcgctggcggccctcgcccggcgcggcgacgtcaagccggag
tcggtcaaggaggcccgggagcgctacgggctgtga
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