KEGG   Streptomyces sp. 769: GZL_p00214
Entry
GZL_p00214        CDS       T03587                                 
Name
(GenBank) type II PKS ketoacyl synthase
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
stre  Streptomyces sp. 769
Pathway
stre00253  Tetracycline biosynthesis
stre01056  Biosynthesis of type II polyketide backbone
stre01100  Metabolic pathways
stre01110  Biosynthesis of secondary metabolites
Module
stre_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:stre00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    GZL_p00214
   00253 Tetracycline biosynthesis
    GZL_p00214
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:stre01004]
    GZL_p00214
   01008 Polyketide biosynthesis proteins [BR:stre01008]
    GZL_p00214
Enzymes [BR:stre01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     GZL_p00214
    2.3.1.260  tetracycline polyketide synthase
     GZL_p00214
Lipid biosynthesis proteins [BR:stre01004]
 Polyketide synthase
  Component type
   GZL_p00214
Polyketide biosynthesis proteins [BR:stre01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     GZL_p00214
    Nonaketide PKS
     GZL_p00214
    Decaketide PKS
     GZL_p00214
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C BLH_phosphatase Thiolase_N
Other DBs
NCBI-ProteinID: AJC62144
UniProt: A0A0A8F2H5
LinkDB
Position
pSGZL:218473..219534
AA seq 353 aa
MDRAAQFAVVCAREAHAASGLDFTHVDPQRVGVTIGSAVGCTMGLEEEYSVVSAAGRDWL
VDHTYAVPQLYGYSVPSSLSAEVAWTVGAEGPATVVSTGCTSGLDSVGYAADLIREGSAD
VMFAGATDAPISPITVACFDAIKATTPRNEDAEHASRPFDRSRNGFVLGEGAAVFVLEEL
QAARRRGVHIYAEIAGFASRSNAFHMTGLRPDGREMAEAISASMSAAAVTAAELGYINAH
GSGTRQNDRHETAAFKRSLGEHAYTTPVSSIKSMIGHSLGAIGSLEIAASLMAIETGVIP
PTANLHEPDPECDLDYVPLVAREQHTDTVLSVGSGFGGFQSAMVLTRPREDRR
NT seq 1062 nt   +upstreamnt  +downstreamnt
atggaccgcgcggctcagttcgcggtggtctgcgcacgggaggcgcacgccgcgagcgga
ctcgacttcacccacgtcgacccgcagcgcgtcggcgtcaccatcggcagcgcggtcggc
tgcaccatggggctggaagaggagtactccgtggtcagcgccgcaggacgggactggctc
gtcgaccacacctacgccgttccgcaactgtacggatactccgtcccgagctcgctcagc
gccgaagtcgcctggactgtgggtgccgaagggccggcgaccgtcgtctcgacggggtgc
acatccggattggactccgtgggctacgcagcggacctgatccgggaaggctccgccgac
gtcatgttcgcgggtgccactgacgcgcccatttcgccgatcaccgtggcgtgcttcgac
gcgatcaaggctacgacgccgcgaaacgaagacgcagagcatgcttcacgcccgttcgac
cgcagccgtaacggctttgtcctgggagaaggcgcagccgtctttgtactggaagaactc
caggccgcacggcgccgcggggtacacatctacgcggagatcgcagggttcgcctcccgc
tccaacgccttccacatgaccggcctgcggccggacggccgggagatggccgaggcgatc
tccgcgtcgatgtcggctgccgcggtcaccgccgccgaactgggatacatcaatgcgcat
ggctcaggcacccggcaaaacgaccgccacgagacggcggcgttcaaaaggagcctgggg
gagcacgcctacaccaccccggtgagctccatcaagtccatgatcgggcactcgctcggt
gccatcggctcactggagatcgcggcttcgctgatggccatcgagaccggagtcatcccg
ccgacggccaaccttcacgagcccgatcccgagtgcgacctcgactacgtccccctcgtg
gcacgcgaacagcacacagacaccgtgctcagcgtgggcagtggattcggcggattccag
agcgcgatggtgctgactcggccccgggaggaccggcggtga

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