KEGG   Streptomyces sp. 4F: ASR50_10640
Entry
ASR50_10640       CDS       T04265                                 
Name
(GenBank) pyruvate dehydrogenase
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
strf  Streptomyces sp. 4F
Pathway
strf00010  Glycolysis / Gluconeogenesis
strf00020  Citrate cycle (TCA cycle)
strf00620  Pyruvate metabolism
strf00785  Lipoic acid metabolism
strf01100  Metabolic pathways
strf01110  Biosynthesis of secondary metabolites
strf01120  Microbial metabolism in diverse environments
strf01200  Carbon metabolism
strf01210  2-Oxocarboxylic acid metabolism
Module
strf_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:strf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    ASR50_10640
   00020 Citrate cycle (TCA cycle)
    ASR50_10640
   00620 Pyruvate metabolism
    ASR50_10640
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    ASR50_10640
Enzymes [BR:strf01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     ASR50_10640
SSDB
Motif
Pfam: PDH_E1_M Transketolase_C_1 Transketolase_N Transketolase_C DUF3135 DUF6245
Other DBs
NCBI-ProteinID: ALV49827
LinkDB
Position
2397413..2400115
AA seq 900 aa
MTDPNAIQPSELDQLPDRDPEETAEWQASLDAVTAAAGPHRAAYLMRRTLERAEGAGVAL
PKLLETDYVNTIPTAAEPAVDGDEALEQRITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRIGEEQLDNFRREAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPISAIYQARFNRYLTSRGIKDVSDSHVWAFLGDGEM
DEPESTTALTLASREQLDNLTFVVNCNLQRLDGPVRANFKIVQELEAQFRGAGWNVIKTL
WGTAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALVEMAKLLSD
DKILECFHLSRGGHESRKVYAAYKAALSHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLTVDEFKAMRDRLELPIPDSRFVDGVVPYVHPGADSPEVRYLQERRAALGGPAPARRVH
PVAPLPQPADKAFAAFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPMGQTYEPVDRDQLMYYKEAKNGQIFNEGITEAGAMAEFIAASTSYST
HGETMIPFYIYYSMFGWQRTGDQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEIAVIVKEGLRRMFGEAKPDEDQNVFYYLTVYNEPLPQPAKPQ
AAGVDEGIVKGLYRFNTAESAGLSPAANAPRIQLLGSGTAIHWALKAQAMLAEEWGVSAD
VWSATSWTELRRDAMEADEALLRGEDRVPYVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDYSSLGADGFGLSDTREAARRHFGVDAESIVVAALAQLARRGEVKATAVKEAREKYGL
NT seq 2703 nt   +upstreamnt  +downstreamnt
atgaccgaccccaacgccatccagccgagcgagctcgaccagctcccggaccgcgacccg
gaggagaccgccgagtggcaggcctccctggacgccgtgaccgcggcggccgggccgcac
cgtgccgcgtacctgatgcggcgcacgctggagcgtgccgagggcgccggcgtcgcgctg
cccaagctgctcgagacggactacgtcaacacgatccccaccgcggccgagcccgcggtg
gacggcgacgaggcgctggagcagcgcatcaccgcctggaaccgctggaacgcggcggcg
atggtgacccgcggcagcaagtacggcgtgggcggccacatcgccaccttcgcctcggcc
gcgtggctctacgagaccggcttcaaccacttcttccgcggcaaggagggggacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgcgttcctc
gacggccggatcggcgaggagcagctcgacaacttccgccgtgaggcgggcggcaacggc
ctgccgtcctacccgcacccgcggcgtctgccctggctgtgggagttccccaccgtgtcg
atgggcctcggcccgatctccgcgatctaccaggcgcgcttcaaccgctacctgaccagc
cgcggcatcaaggacgtctccgactcccacgtgtgggcgttcctcggcgacggcgagatg
gacgagcccgagtcgacgaccgcgctcaccctcgcctcccgcgagcagctggacaacctg
accttcgtcgtcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttcaag
atcgtccaggagctggaggcccagttccgcggcgccggctggaacgtgatcaagaccctg
tggggcaccgcctgggacgagctgttccagctcgacaccacgggcgccctggtccgccgc
ctccgcgaggtgccggacgcgcaggtgcagacgtaccagacgcgcgacgccgcctacatc
cgcgaggacttcttcggcaaggacccggcgctcgtcgagatggcgaagctgctgagcgac
gacaagatcctcgagtgcttccacctctcgcgcggcggccacgagtcccgcaaggtgtac
gccgcgtacaaggccgcgctgtcccacaagggcgcgccgaccgtgatcctggcgcagacc
gtcaagggccacaccctcggtgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaaggcgatgcgcgaccggctcgagctgccgatcccggac
tcgcggttcgtcgacggcgtggtgccctacgtgcacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgtgccgccctcggcggccccgccccggcccgccgcgtgcac
ccggtcgcgccgctgccgcagccggccgacaaggcgttcgccgcgttcgacaagggctcc
ggctcgcagaacgtggccaccacgatggcgttcgtccgcctcgtcaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagagcctcttcccgtccctcggcatctactcgccgatgggccagacgtacgagccg
gtcgaccgtgaccagctgatgtactacaaggaagccaagaacggccagatcttcaacgag
gggatcaccgaggccggcgccatggccgagttcatcgccgcgtcgacgtcgtactcgacg
cacggcgagacgatgatcccgttctacatctactactcgatgttcggctggcagcgcacc
ggcgaccagatgtggcagctcggcgaccagctgggccgcggcttcctggtcggcgccacc
gcgggccgcaccacgctgaccggcgagggcctccagcacgccgacggccactcccccgtc
atcgcggcgaccaacccggccgccctgacgtacgacccggcgttcgcctacgagatcgcg
gtcatcgtcaaggagggtctgcgccggatgttcggcgaggcgaagccggacgaggaccag
aacgtcttctactacctgacggtctacaacgagccgctgccgcagcccgcgaagccgcag
gcggcgggcgtcgacgagggcatcgtcaagggcctgtaccgcttcaacacggcggagtcc
gccggcctgtcgcccgccgccaacgccccgcgcatccagctgctgggctccggcacggcg
atccactgggcgctgaaggcgcaggcgatgctcgccgaggagtggggcgtgtccgccgac
gtgtggtccgccacctcgtggaccgagctgcgccgcgacgcgatggaggccgacgaggcc
ctgctccgcggcgaggaccgggtgccgtacgtccggcaggcgctccagggcgccgagggc
ccggtgctggcggtgtccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactactcctcgctgggcgccgacggcttcggcctgtcggacacccgtgaggcg
gcccgccgccacttcggcgtggacgccgagtcgatcgtcgtcgcggccctggcccagctc
gcccgccgcggcgaggtgaaggccaccgcggtgaaggaggcccgggagaagtacggcctg
tag

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