Streptomyces sp. 4F: ASR50_24030
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Entry
ASR50_24030 CDS
T04265
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
strf
Streptomyces sp. 4F
Pathway
strf00020
Citrate cycle (TCA cycle)
strf00630
Glyoxylate and dicarboxylate metabolism
strf00785
Lipoic acid metabolism
strf01100
Metabolic pathways
strf01110
Biosynthesis of secondary metabolites
strf01120
Microbial metabolism in diverse environments
strf01200
Carbon metabolism
strf01210
2-Oxocarboxylic acid metabolism
Module
strf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
strf_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
strf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ASR50_24030 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
ASR50_24030 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ASR50_24030 (kgd)
Enzymes [BR:
strf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ASR50_24030 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ASR50_24030 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ASR50_24030 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ASR50_24030 (kgd)
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Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ALV52165
LinkDB
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Position
complement(5337637..5341434)
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AA seq
1265 aa
AA seq
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MSPQSPSNSSISTDTDQAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAPASSAPAGDAAAGAAVTPTAPSQPAPPAKAQAPAQPAPAAKAPAQTQAPAQAKAPAQP
AKQAAPAAKPAPARKAEPAGEAKSGPEQVTLRGPSAAVAKNMDASLELPTATSVRAVPVK
LLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNNSYAKVDGKPTLVKPEHI
NLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDNKLTMDDFTGVTVS
LTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDH
RVIQGAASGEFLRQVANLLLGENNFYDEIFEALRIPYEPVRWLKDIDASHDDDVTKAARV
FDLIHSYRVRGHVMADTDPLEYKVRKHPDLDIVEHGLTLWDLEREFAVGGFAGKSMMKLR
DILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERGHTKPEREEQLRILRRLNAAEAFE
TFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANIVGKS
YAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVLE
GVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINN
QVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVID
LICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQG
QLEKVFTEVREATSQPATAVPSDPQAEFPVAVNTAVSSEIVKRIAESQVNIPDHVTVHPR
LLPQLQRRATMVEDGTIDWGMGETLAIGSLLLEGVPVRLAGQDSQRGTFGQRHAVIIDNK
TGEEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDFVNGAQ
TVVDEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTSP
SNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAAAKADEFTTGQFRPVIGDDTVDPAAVK
KVVFCAGKVYYDLAAERKKRGADDTAIIRIERLYPLPGAELQAEIKKYPNAEKYLWAQEE
PANQGAWPFIALNLIDHLDLAVGADLPHDERLRRISRPHSSSPAVGSAKRHQAEQEQLVR
EVFEA
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcgggaaag
aaccccgctgcggccttcggtgccaacgaatggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtggaccgagcctggtgggacttcttcgccgactacaagccg
ggcgctcccgcgtcctcggctccggcgggtgacgcggccgcgggggccgcggtgaccccc
accgctccgtcccagccggccccgcccgcgaaggctcaggcgcccgcgcagcccgccccg
gccgccaaggccccggcgcagacgcaggcccccgcgcaggcgaaggccccggcccagccg
gcgaagcaggccgctcccgccgccaagccggcgccggccaggaaggccgagcccgcgggc
gaggcgaagagcggtcccgagcaggtcaccctgcgcggcccgtccgccgcggtggccaag
aacatggacgcctcgctggagctgcccacggccacgtccgtgcgcgcggtcccggtgaag
ctgctgttcgacaaccgcatcgtcatcaacaaccacctgaagcgcgcgcggggcgggaag
atctccttcacgcacctcatcggctacgccatggtgcaggccatcaaggccatgccgtcg
atgaacaactcgtacgccaaggtggacggcaagccgaccctggtgaagccggagcacatc
aacctcggtctcgccatcgacctggtcaagcccaacggcgaccgccagctcgtcgtcgcg
gcgatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggacatc
gtccgtcgcgcccgcgacaacaagctgacgatggacgacttcaccggtgtcacggtctcc
ctgaccaaccccggcggcctcggcaccgtccactccgtgccgcgtctgatgcccggccag
tccgtgatcatgggcgtcggctccatggactacccggcggagttccagggcacctcccag
gacaccctgaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctacgaccac
cgggtgatccagggcgccgcctccggcgagttcctgcgccaggtcgcgaacctcctcctc
ggcgagaacaacttctacgacgagatcttcgaggccctgcgcatcccctacgagccggtc
cgctggctcaaggacatcgacgccagccacgacgacgacgtcaccaaggccgcccgggtc
ttcgacctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctc
gagtacaaggtccgcaagcaccccgacctggacatcgtcgagcacggcctcaccctgtgg
gacctggagcgcgagttcgccgtcggcggtttcgccggcaagtcgatgatgaagctgcgc
gacatcctcggcgtgctccgcgactcgtactgccgcaccaccggcatcgagttcatgcac
atccaggaccccaagcagcgcaagtggatccaggaccgcgtggagcgcggccacaccaag
ccggagcgcgaggagcagctgcgcattctgcgccggctgaacgcggcggaggccttcgag
accttcctgcagaccaagtacgtcggccagaagcgcttctcgctggagggcggcgagtcc
gtcatcccgctgctcgacgcggtgctggactcggccgccgagtcccgcctggacgaggtc
gtcatcggcatggcccaccgcggccgcctcaacgtcctcgccaacatcgtcggcaagtcg
tacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctcc
ggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggcctggacggcgagcag
atcaaggtctcgctggtcgccaacccctcgcacctggaggcggtcgacccggtcctggag
ggcgtcgcccgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtcctg
ccggtggccatccacggcgacgcggccttcgcgggccagggcgtggtggccgagaccctg
aacatgtcgcagctgcgcggctaccgcaccggcggcaccgtgcacgtcgtcatcaacaac
caggtcggcttcaccgcggcccccgagtcctcgcgctcctccatgtacgcgacggacgtg
gcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccggaggcggtggtg
cgcgtcgcgcgcctggccttcgagttccgccaggcgttcaacaaggacgtggtgatcgac
ctcatctgctaccgccgccgcggtcacaacgagtccgacaacccggccttcacccagccg
ctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctc
atcggtcgcggcgacatcaccctggaagaggccgagcaggcgctgcaggactaccagggc
cagctggagaaggtcttcaccgaggtccgcgaggccacctcgcagccggccacggccgtc
ccgtcggacccgcaggccgagttcccggtcgccgtgaacaccgcggtgagctcggagatc
gtgaagcggatcgccgagtcccaggtcaacatcccggaccacgtcaccgtccacccgcgt
ctgctgccgcagctgcagcgccgggccacgatggtcgaggacggcacgatcgactggggc
atgggcgagaccctcgccatcggctccctcctgctggagggcgtcccggtccggctggcc
ggccaggactcgcagcgcggcaccttcggccagcgccacgcggtgatcatcgacaacaag
acgggcgaggagtacacgccgctccagtacctctccgaggaccaggcgcgcctcaacgtc
tacaactcgctgctgtccgagtacgcggccatgggcttcgagtacggctactcgctggcc
cgcccggacgcgctcgtgctctgggaggcgcagttcggcgacttcgtcaacggcgcgcag
acggtcgtggacgagttcatctcgtcggccgagcagaagtgggcccagacctccggtgtg
gtcctgctcctcccgcacggctacgagggccagggcccggaccactcctcggcccgcccg
gagcgcttcctgcagctctgcgcccagaacaacatgacggtcgccatgccgacctcgccg
tcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtg
gtcttcacgccgaagtcgatgctgcgtctcaaggccgccgcggcgaaggcggacgagttc
acgacgggccagttccgcccggtcatcggcgacgacacggtcgacccggccgccgtgaag
aaggtcgtcttctgcgccggcaaggtctactacgacctggccgccgagaggaagaagcgc
ggcgcggacgacacggcgatcatccgcatcgagcgcctgtacccgctgccgggtgccgag
ctccaggcggagatcaagaagtacccgaacgccgagaagtacctgtgggcgcaggaggag
ccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccacctggacctg
gcggtcggcgccgacctgccgcacgacgagcgtctgcgccgcatctcgcggccgcacagc
tcgtccccggcggtcggctccgccaagcgccaccaggccgagcaggagcagctggtgcgc
gaggtcttcgaggcctga
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