Streptomyces sp. JH002: H7827_07695
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Entry
H7827_07695 CDS
T11115
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
strj Streptomyces sp. JH002
Pathway
strj00020
Citrate cycle (TCA cycle)
strj00630
Glyoxylate and dicarboxylate metabolism
strj00785
Lipoic acid metabolism
strj01100
Metabolic pathways
strj01110
Biosynthesis of secondary metabolites
strj01120
Microbial metabolism in diverse environments
strj01200
Carbon metabolism
strj01210
2-Oxocarboxylic acid metabolism
Module
strj_M00009
Citrate cycle (TCA cycle, Krebs cycle)
strj_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
strj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
H7827_07695
00630 Glyoxylate and dicarboxylate metabolism
H7827_07695
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
H7827_07695
Enzymes [BR:
strj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
H7827_07695
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
H7827_07695
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
H7827_07695
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
H7827_07695
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
XVJ75501
LinkDB
All DBs
Position
1799908..1803660
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AA seq
1250 aa
AA seq
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MSPQSTDTSGVETEQAGSQKSPAAGFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GQAKQTGDGSPAPAKAPPTTAGQAPAAPAAPAAPAPAAAPAPAAPAAKPAAAAPAKAPAK
APAKEVSEGPELITLRGPAAAVAKNMNASRDLPTATSVRAVPVKLLFDNRIVINNHLKRA
RGGKVSFTHLIGYAMVQALKAMPSMNYSYAEKDGKPTLVKPEHVSLGLAIDLVKPNGDRQ
LVVAGIKKAETLTFFEFWQAYEDIVRRARSGKLTMEDFSGVTASLTNPGGIGTVHSVPRL
MPGQGVILGVGAMEYPAEFQGSSQATLNRLGISKVMTLTSTYDHRVIQGAASGEFLRQIS
QLLLGQHNFYDDIFEALRIPYEPVRWHQDIDVNHDDEVTKAARVFDLIHSYRVRGHLMAD
TDPLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFNGKSMMTLRDILGVLRDSYCRTTGI
EYMHIQDPKERKWIQDRVERGHTPPEREEQLRILRRLNASEAFETFLQTKYVGQKRFSLE
GGETVIPLLDSVLDEAAAASLDEAVIGMAHRGRLNVLANVVGKSYAQIFREFEGNLDPKS
MHGSGDVKYHLGTEGTFTGLSGEQITVSLAANPSHLEAVDPIVEGVARAKQDIIGKGGKD
FTVLPILIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGYTATAAAARSSMY
CTDVARMIEAPIFHVNGDDPEAVCRVARLAFEYRQAFNKDVVIDLVCYRRRGHNETDNPS
FTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFKEVREATGSP
APAEVPAPQAEFPVAVETAVSSEVVKRIAESQVNIPDRITVHPRLLPQMQRRAAMVEEGT
IDWAMGELLAVGSLLMEGTTVRLAGQDSRRGTFGQRHAVLIDRNTGEDYTPLLYLSEDQA
RFNVYDSLLSEYAAMGFEYGYSLARPDSLVMWEAQFGDFVNGASTVVDEFISSAEQKWGQ
TSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAAPTLPSNYFHLLRWQVHNPHH
KPLVVFTPKSMLRLKAAASKAEEFTTGGFRPLIGDATVDPDQVRKVVFCSGKVYYDLEAE
RTKRGVTDTAIIRLERLYPLPTDEIRTEIARFRNAATYVWAQEEPANQGAWPFIALNLVD
HLQLIIGSDSVAGADRLRRVSRPASSSPAVGSAKRHQVEQQTLLNEVFEL
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtccacggacacctcgggtgtcgagaccgaacaagccggatctcagaag
agccctgccgccggcttcggtgccaacgaatggctcgtcgacgagatctatcagcagtac
ctccaggacccgaactcagtagaccgggcttggtgggacttcttcgccgactacaagccg
ggccaggccaagcagaccggggacggctcgcccgcccccgccaaggccccgccgacgacc
gcgggtcaggcccccgcggcgcccgcggctccggccgcaccggcaccggccgctgctccg
gccccggcggcacccgccgccaagccggccgccgcggctccggcgaaggcaccggccaag
gccccggccaaggaggtgtccgagggccccgagctgatcacactgcgcggtccggccgcc
gcggtcgcgaagaacatgaacgcctcccgcgacctgccgaccgccacgtcggtccgtgcc
gtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctgaagcgcgcg
cgcggcgggaaggtgtccttcacgcacctcatcggctacgccatggtgcaggcgctgaag
gcgatgccgtccatgaactactcctacgcggagaaggacggcaagccgaccctcgtcaag
ccggagcacgtcagcctgggcctggccatcgacctggtcaagcccaacggtgaccggcag
ctggtggtggccggcatcaagaaggcggagacgctcaccttcttcgagttctggcaggcg
tacgaggacatcgtgcgccgcgcccgctccgggaagctgacgatggaggacttctccggc
gtcaccgcctccctgaccaaccccggcggcatcggcaccgttcactcggtgccgcgcctg
atgcccggccagggcgtcatcctgggcgtcggcgcgatggagtacccggcggagttccag
ggttcctcccaggccacgctcaaccgcctgggcatctccaaggtgatgaccctcaccagc
acctacgaccaccgggtcatccagggcgccgcctccggtgagttcctgcgccagatctcg
cagttgctgctcggtcagcacaacttctacgacgacatcttcgaggcgctgcggatcccc
tacgaaccggtccgctggcaccaggacatcgacgtcaaccacgacgacgaagtcaccaag
gccgcccgggtgttcgacctgatccactcctaccgggtgcgcggccacctcatggccgac
accgacccgctggagtacaagcagcgcaagcaccccgacctggacatcaccgagcacggc
ctcaccctgtgggacctggaacgtgagttcgcggtcggcggcttcaacggcaagtcgatg
atgacgctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcatc
gagtacatgcacatccaggatcccaaggaacgcaagtggatccaggaccgcgtcgagcgc
gggcacaccccgcccgagcgcgaggagcagctgcgcatcctgcgccggctgaacgcctcc
gaggcgttcgagacgttcctgcagaccaagtacgtgggccagaagcggttctcgctggag
ggcggcgagaccgtcatcccgctgctcgactccgtgctggacgaggccgccgccgcgtcc
ctggacgaggccgtcatcggcatggcccaccgcggccggctgaacgtgctggccaacgtc
gtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcg
atgcacggctccggcgacgtgaagtaccacctgggcaccgagggcaccttcaccggcctg
tccggcgagcagatcaccgtgtcgctggcggccaacccctcccacctggaggcggtcgac
ccgatcgtcgagggtgtcgcgcgcgccaagcaggacatcatcggcaagggcggcaaggac
ttcaccgtcctgccgatcctcatccacggtgacgcggcgttcgcgggccagggtgtggtc
gccgagacgctgaacatgtcgcagctgcgcggctaccgcaccggcggcaccgtgcacatc
gtcatcaacaaccaggtcgggtacacggcgacggccgccgccgcccgttcctcgatgtac
tgcaccgacgtggcgcggatgatcgaggccccgatcttccacgtcaacggtgatgacccc
gaggccgtgtgccgcgtggcgcggctggccttcgagtaccggcaggcgttcaacaaggac
gtcgtcatcgacctcgtctgctaccggcgccgcgggcacaacgagacggacaacccgtcc
ttcacccagcccctgatgtacgacctgatcgacaagaagcgttcggtgcgcaagctgtac
accgaatcgctgatcggccggggcgacatcaccctggaggaggccgagcaggcgctccag
gacttccagggccagctggagaaggtcttcaaggaggtccgcgaggccaccggttcgccg
gcccccgccgaggtccccgccccgcaggcggagttcccggtggcggtggagacggccgtc
agctccgaggtcgtcaagcggatcgccgagtcgcaggtcaacatccccgaccggatcacc
gtgcacccgcgtctgctgccgcagatgcagcgccgcgcggcgatggtcgaggaggggacg
atcgactgggcgatgggcgaactgctcgcggtcggctcgctgctgatggagggcacgacc
gtccgcctggccggccaggactcgcggcgcggcaccttcggccagcggcacgcggtgctg
atcgaccggaacaccggcgaggactacaccccgctgctgtacctgagcgaggaccaggcc
cggttcaacgtctacgactcgctgctgagcgagtacgcggcgatgggcttcgagtacggc
tactcgctggcccgcccggactccctggtgatgtgggaggcgcagttcggtgacttcgtc
aacggcgcctcgaccgtcgtggacgagttcatctcctcggcggagcagaagtggggccag
acctccggggtcaccctgctgctgccgcacgggtacgagggccagggcccggaccactcc
tcggcccgcatcgagcggttcctccagctgtgcgcgcagaacaacatgacggtcgcggcg
ccgacgctgccgtcgaactacttccatctgctgcgctggcaggtgcacaacccgcaccac
aagccgctggtcgtcttcaccccgaagtcgatgctgcggctgaaggcggcggcctccaag
gcggaggagttcaccaccggtggcttccggccgctgatcggtgacgcgacggtggacccg
gaccaggtgcgcaaggtggtgttctgctccggcaaggtctactacgacctggaggcggag
cgcaccaagcgcggggtcacggacacggcgatcatccgtctggagcggctctacccgctg
ccgacggacgagatccgcaccgagatcgcccggttccgcaacgcggccacctacgtgtgg
gcgcaggaggagccggccaaccagggtgcgtggccgttcatcgcgctgaacctggtggac
cacctccagctcatcatcggctcggactccgtggcgggcgccgaccggctgcggcgggtg
tcgcgtccggcgtcgtcctcgcccgcggtgggttcggccaagcggcaccaggtcgagcag
cagaccctgctgaacgaggtgttcgagctgtag
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