Streptomyces sp. JH002: H7827_23135
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Entry
H7827_23135 CDS
T11115
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
strj Streptomyces sp. JH002
Pathway
strj00010
Glycolysis / Gluconeogenesis
strj00020
Citrate cycle (TCA cycle)
strj00620
Pyruvate metabolism
strj00785
Lipoic acid metabolism
strj01100
Metabolic pathways
strj01110
Biosynthesis of secondary metabolites
strj01120
Microbial metabolism in diverse environments
strj01200
Carbon metabolism
strj01210
2-Oxocarboxylic acid metabolism
Module
strj_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
strj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
H7827_23135 (aceE)
00020 Citrate cycle (TCA cycle)
H7827_23135 (aceE)
00620 Pyruvate metabolism
H7827_23135 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
H7827_23135 (aceE)
Enzymes [BR:
strj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
H7827_23135 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
XVJ78245
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Position
complement(5039010..5041688)
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AA seq
892 aa
AA seq
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MPDPVRLRLSALDQLPDRDPEETAEWGASLDAVAAAAGPHRAGQLVRRTVEHAQASGIDV
PSLLETDYINSIPTGAEPDFPGDEALEARVTAWNRWNAAAMVTRGARYGVGGHIATFASA
AWLYETGFQHFFRGKDAADAPGSGDQLFIQGHASPGIYARAFLDGRLTEAHLDNFRQESG
GAGLPSYPHPRRLPWLWEFPTVSMGIGPLSAIYQARFNRYLENRGIKDTSASHVWAFLGD
GEMDEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRAAGWNVI
KTLWGSAWDDLLRADTTGALVRRLREVPDAQFQTYATRDVAYIRDHFFGTDPALAQLGAS
LPDAKIAECFHTSRGGHEPRKVYAAYRAAVEFKGAPTVVLAQTVKGHTLGDGFQSRNANH
QMKKLTMEQFRTMRDLLELPIPDSELSGDLVPYAHPGPDSPEVRYLQERRAALGGPAPAR
RVHQVVLPEPSEKAFKALEKGSGSQEVATTMVIVRLVKDLMREKESGRRWVPIVPDEART
FGMESMFPSAGIYSPLGQTYESVDRDQLLHYKEAVNGQILNEGITEAGSMADFTAAATAY
ATHGEPMIPFYIFYSMFGWQRTGDQMWALGDQLGRGFIVGATAGRTTLTGEGLQHADGHS
PLIASTNPAALTYDPAFAYEVGVIVKDGLRRMYGPDAEDVFYYLTVYNEPKPQPAMPEGV
EEGILRGLYRFNEGQAPSAEAPRVQLMASGTAIHWVLEAQRLLSEQWGVAADVWSATSWS
ELRRDALSCDAAQLRGEDRVPYVTRALRGARGPVLAVSDWMRAVPDQIGQWVEQDYSSLG
TDGFGLSDTREAARRHFGVDPQSIVVAALDRLARSGEVKRETVLAAREAYGL
NT seq
2679 nt
NT seq
+upstream
nt +downstream
nt
atgcccgatcccgtacgccttcggctctccgcgctcgatcagctgccggatcgtgatccc
gaggagaccgccgagtggggcgcgagcctcgacgccgtggccgccgccgccggcccgcac
cgggccggccaactggtgcgccgtacggtggagcacgcccaggccagcgggatcgatgtg
ccctcgctgctggagacggattacatcaactccatccccaccggcgccgagcccgacttc
cccggtgacgaggccctggaggcccgcgtcaccgcctggaaccggtggaacgccgccgcg
atggtcacccggggtgcccggtacggcgtgggcggccacatcgccaccttcgcctccgcc
gcctggttgtacgagaccgggttccagcacttcttccgcggcaaggacgcggcggacgcg
cccggctccggcgaccagctgttcatccagggccacgcctcccccggcatctacgcccgc
gccttcctcgacggccgcctcaccgaggcgcacctggacaacttccgccaggagtcgggc
ggcgccggcctgccctcgtacccgcacccgcggcggctgccgtggctgtgggagttcccc
accgtctccatgggcataggcccgctgtcggcgatctaccaggcgcggttcaaccgctac
ctggagaaccgcggcatcaaggacacctccgcctcgcacgtgtgggcgttcctgggcgac
ggcgagatggacgagcccgagtcgaccgccgcgctggcgctggccgggcgtgagggtctg
gacaacctcaccttcgtcatcaactgcaacctccagcggctcgacggcccggtgcgcgcg
aacttcaagatcgtgcaggaactggaggcccagttccgggcggccggctggaacgtcatc
aagaccctgtggggctccgcctgggacgacctgctgcgggccgacaccaccggcgcgctg
gtacggcggctgcgggaggtcccggacgcgcagttccagacgtacgccacccgcgacgtc
gcctacatccgcgaccacttcttcggcaccgacccggcgctggcccagctgggcgcctcg
ctgccggacgcgaagatcgccgagtgcttccacacctcgcgcggtggccacgagccccgc
aaggtgtacgccgcgtaccgggcggccgtggagttcaagggcgccccgaccgtggtgctg
gcccagaccgtcaagggccacaccctgggcgacggcttccagtcgcgcaacgccaaccac
cagatgaagaagctcacgatggagcagttccgcaccatgcgggacctgctggagcttccc
atcccggacagcgagctgtccggcgacctggtgccctacgcccaccccggccccgactcc
cccgaggtgcgctacctccaggagcggcgcgcggccctgggcggtccggcgccggcccgc
cgggtgcaccaggtggtgctgccggagccgtccgagaaggcgttcaaggcgctggagaag
ggctcgggctcgcaggaggtcgccaccaccatggtgatcgtccggctggtcaaggacctg
atgcgggagaaggagtcggggcggcgctgggtgccgatcgtccccgacgaggcccgtacc
ttcggcatggagtcgatgttcccgtccgccgggatctactcgccgctgggccagacctac
gagtcggtcgaccgcgaccagctgctgcactacaaggaagccgtcaacggccagatcctg
aacgaggggatcaccgaggccggttcgatggccgacttcacggcggcggccacggcgtac
gccacgcacggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcag
cgcaccggcgaccagatgtgggcgctgggcgaccagctgggccgcggcttcatcgtgggc
gccacggccggccgcaccacgctgaccggtgagggcctgcagcacgcggacggtcactcg
ccgctgatcgcctccaccaacccggcggcgctgacgtacgacccggcgttcgcgtacgag
gtgggcgtcatcgtcaaggacggtctgcgccggatgtacggcccggacgccgaggacgtc
ttctactacctgacggtctacaacgagccgaagccgcagcccgccatgcccgagggcgtg
gaggaaggcattctgcgcggcctgtaccgcttcaacgaggggcaggccccctcggcggag
gcgccgcgggttcagctgatggcgtcgggtacggccatccactgggtgctcgaggcccag
cgacttctgtccgagcagtggggtgtggccgccgacgtgtggtccgccacctcctggagc
gagctgcgccgtgacgccctgtcctgtgacgcggcgcagcttcgaggggaagaccgggtc
ccgtacgtgacgcgtgcgctgcggggcgcgcggggcccggtcctcgccgtgagcgactgg
atgcgggcggtgcccgaccagatcggtcagtgggtcgagcaggactactcctcgctcggc
acggacggcttcggcctctccgacacccgtgaggcggcccgccggcacttcggcgtggac
ccgcagtcgatcgtggtggcggcgctggaccggctggcccggtccggtgaggtcaagcgc
gagacggtgctggcggcgcgcgaggcctacggcctgtaa
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