KEGG   Streptomyces sp. JH002: H7827_26295
Entry
H7827_26295       CDS       T11115                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
strj  Streptomyces sp. JH002
Pathway
strj00270  Cysteine and methionine metabolism
strj00450  Selenocompound metabolism
strj00670  One carbon pool by folate
strj01100  Metabolic pathways
strj01110  Biosynthesis of secondary metabolites
strj01230  Biosynthesis of amino acids
strj04980  Cobalamin transport and metabolism
strj04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:strj00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    H7827_26295 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    H7827_26295 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    H7827_26295 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    H7827_26295 (metH)
   04980 Cobalamin transport and metabolism
    H7827_26295 (metH)
Enzymes [BR:strj01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     H7827_26295 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding CdhD Tautomerase_2
Other DBs
NCBI-ProteinID: XVJ78820
LinkDB
Position
5732092..5735604
AA seq 1170 aa
MASPILSPHTQADRAAALRRAFASRVVVADGGMGTMLQAAEPSLDDFEQLEGCNEVLNVT
RPDIVRSVHQEYFDAGVDCVETNTFGANLAALGEYDIPERIAELSEAGARIARETADDCA
ARDGRQRWVLGSIGPGTKLPTLGHIRYADLRDAYQQNAEGLIAGGADALLVETAQDLLQT
KAAVLGARRAAAATGVDLPLVVQVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATG
PAEMSEHLRYLSQHATIPISCMPNAGLPVLGKDGAHYPLGPAELADAHQTFIGEFGLSLI
GGCCGTTPEHLRQVVERVRGLTPGARDPRPEPGAASLYQTVPFRQDASYLAIGERTNANG
SKKFREAMLEGRWEDCVELAREQIREGAHLLDLCVDYVGRDGAADMSELAGRLATASTLP
IVLDSTEPAVLEAGLERLGGRAVINSVNYEDGDGPDSRFAKVTRMAVEHGAALMALTIDE
RGQARTPEDKVAIAERIIADLTGNWGVAESDIIIDCLTFTICTGQEESRRDGVHTIEAIR
ELKRRHPQVQTTLGLSNISFGLNPAARLVLNSVFLDECVKAGLDSAIVHAAKILPIARIE
DEQVQVALDLIHDRRREGYDPLQRFLELFEGVDAKSMRAGKTEELLALPLEERLRRRIVD
GERKGLEADLDEALTTRPALEIVNETLLEGMKTVGELFGSGQMQLPFVLQSAEVMKTAVA
HLEPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVTAILDA
AEEHRADVIGMSGLLVKSTVIMKENLEELNQRGMAADYPVILGGAALTRAYVEQDLHEVY
QGEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKKRRVAARPAALPQEDTEEPVGRSA
TATDVPLPTAPFLGTRVIKGIPLKDYAAWLDEDALFKGQWGLKGSRSGEGPDYEELLETE
GRPRLRGWLDRLHTDNLLEAAVVYGYFPCHAEGQDLVILDEDGKERTRFTFPRQRRGRRL
CLADFFRPADSGETDVVALQAVTVGSRVSGATAELFAADAYRDYLELHGLSVQLAEALAE
FWHARVRAELGIGGSDPAALAGMFRTEYQGCRYSLGYPACPDLEDRAKIAELLQPERIGV
TLSEEFQLHPEQSTDAIVLHHPEANYFNAR
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggcctcgcccatcctgtccccgcacacccaggccgaccgcgccgccgcactgcgccgg
gccttcgcctcccgcgtcgtcgtcgccgacggcggcatgggcaccatgctccaggccgcc
gagccctccctggacgacttcgagcagctggaagggtgcaacgaggtcctgaacgtcacc
cgcccggacatcgtgcgctccgtccaccaggagtacttcgacgccggcgtggactgcgtg
gagaccaacaccttcggcgccaacctcgccgcactcggcgagtacgacatccccgaacgc
atcgccgagctctccgaggccggtgcccgcatcgcccgcgagaccgccgacgactgcgcc
gcgcgcgacggacggcagcgctgggtactgggctccatcggccccggcaccaagctgccc
accctcggccacatccgctacgccgacctgcgcgacgcgtaccagcagaacgcggagggc
ctgatcgccggcggcgccgacgccctgctggtggagaccgcccaggacctgctccagacc
aaggccgccgtgctcggcgcccgccgcgccgcggccgccaccggcgtcgacctgccgctc
gtcgtccaggtcaccgtcgagaccaccggcaccatgctgctgggctccgagatcggcgcc
gccctcaccgccctggaaccgctgggcatcgacatgatcggcctgaactgcgccaccggg
ccggccgagatgagcgagcacctgcgctatctctcccagcacgccaccatccccatctcc
tgcatgcccaacgccgggctgcccgtcctcggcaaggacggcgcccactacccgctgggc
cccgccgagctcgccgacgcccaccagaccttcatcggcgaattcggcctctccctgatc
ggcggctgctgcggcaccacccccgagcacctgcggcaggtcgtggagcgggtgcgcggg
ctgacccccggcgcgcgcgacccgcgccccgagcccggcgccgcctccctctaccagacc
gtgccgttccggcaggacgcctcctacctcgccatcggcgagcgcaccaacgcgaacggc
tccaagaagttccgcgaggccatgctggagggccgctgggaggactgcgtcgagctggcc
cgcgaacagatccgcgagggcgcccacctgctcgacctgtgcgtggactacgtcggccgc
gacggcgccgccgacatgtccgaactggccggccggctcgccaccgcctccaccctgccc
atcgtgctggactccaccgagcccgccgtcctggaggccggcctggagcggctcggcggc
cgggccgtcatcaactccgtgaactacgaggacggcgacggccccgactcgcggttcgcc
aaggtcacccggatggcggtggagcacggcgcggcactgatggccctcaccatcgacgaa
cgcggccaggcccgcacccccgaggacaaggtcgccatcgccgagcgcatcatcgccgac
ctcaccggcaactggggcgtggccgagagcgacatcatcatcgactgcctcaccttcacc
atctgcaccggccaggaggagtcccgccgcgacggggtgcacaccatcgaggccatcagg
gagctgaagcggcgccacccccaggtgcagaccaccctgggcctgtccaacatctccttc
ggcctcaacccggcggcccggctcgtcctcaactcggtcttcctcgacgaatgcgtcaag
gccggcctggactccgccatcgtgcacgccgccaagatcctgcccatcgcccggatcgag
gacgaacaggtccaggtcgccctcgacctcatccacgaccggcgccgagagggctacgac
ccgctccagcgcttcctcgaactcttcgagggcgtggacgccaagtccatgcgggccggc
aagaccgaggaactgctcgccctgcccctggaggagcggctgcgccggcgcatcgtcgac
ggcgagcgcaagggactggaggccgacctcgacgaggcgctcaccacccgccccgccctg
gagatcgtcaacgagaccctgctggagggcatgaagacggtcggcgagctgttcggttcg
ggacagatgcagctgcccttcgtgctccagtccgccgaggtcatgaagaccgccgtcgcc
cacctcgaaccgcacatggagaagtccgacgacgagggcaagggcaccatcgtgctcgcc
accgtgcgcggcgacgtccacgacatcggcaagaacctggtcgacatcatcctgtccaac
aacggctacaacgtcgtcaacctcggcatcaagcagccggtgaccgccatcctggacgcc
gccgaggaacaccgcgccgatgtcatcgggatgtccgggctgctggtgaagtccacggtg
atcatgaaggagaacctggaggagctcaaccagcgcggcatggccgccgactacccggtc
atcctcggcggcgccgccctcacccgcgcctatgtcgagcaggacctgcacgaggtctac
cagggcgaggtccgctacgcccgcgacgccttcgagggcctgcggctgatggacgccctg
atcgccgtcaagcgcggcgtgcccggcgccaccctccccgagctgaagaagcgccgggtc
gccgcccgccccgccgccctgccgcaggaggacaccgaggagccggtgggccgctcggcc
accgccaccgacgtaccgctgcccaccgccccgttcctcggcacccgcgtcatcaagggc
atcccgctcaaggactacgccgcctggctggacgaggacgccctcttcaagggccagtgg
gggctcaagggcagccgcagcggcgagggccccgactacgaggaactgctggagaccgag
ggacgcccccggctgcgcggctggctggaccggctgcacaccgacaacctcctggaggcg
gccgtcgtctacggctacttcccctgccacgccgagggccaggacctggtgatcctcgac
gaggacggcaaggaacgcacccgcttcaccttcccccgccagcgccgcggccggcggctg
tgcctggccgacttcttccgcccggcggacagcggcgagacggacgtggtcgccctgcag
gccgtcaccgtcggctcccgggtctccggcgccaccgctgaactgttcgccgccgacgcc
taccgcgactatctggagctgcacgggctgtccgtccagctcgccgaggcgctcgccgag
ttctggcacgcccgggtccgcgccgaactgggcatcggcggctccgacccggccgccctg
gccggaatgttccgcaccgagtaccagggctgccggtactccctgggctaccccgcctgc
cccgacctggaggaccgcgccaagatcgccgagctgctccagcccgagcggatcggggtc
accctgtccgaggagttccagctgcaccccgagcagtccaccgacgcgatcgtcctgcac
caccccgaggccaactacttcaacgcccgctga

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