Streptomyces sp. JH002: H7827_26295
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Entry
H7827_26295 CDS
T11115
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
strj Streptomyces sp. JH002
Pathway
strj00270
Cysteine and methionine metabolism
strj00450
Selenocompound metabolism
strj00670
One carbon pool by folate
strj01100
Metabolic pathways
strj01110
Biosynthesis of secondary metabolites
strj01230
Biosynthesis of amino acids
strj04980
Cobalamin transport and metabolism
strj04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
strj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
H7827_26295 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
H7827_26295 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
H7827_26295 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
H7827_26295 (metH)
04980 Cobalamin transport and metabolism
H7827_26295 (metH)
Enzymes [BR:
strj01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
H7827_26295 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
CdhD
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
XVJ78820
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All DBs
Position
5732092..5735604
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AA seq
1170 aa
AA seq
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MASPILSPHTQADRAAALRRAFASRVVVADGGMGTMLQAAEPSLDDFEQLEGCNEVLNVT
RPDIVRSVHQEYFDAGVDCVETNTFGANLAALGEYDIPERIAELSEAGARIARETADDCA
ARDGRQRWVLGSIGPGTKLPTLGHIRYADLRDAYQQNAEGLIAGGADALLVETAQDLLQT
KAAVLGARRAAAATGVDLPLVVQVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATG
PAEMSEHLRYLSQHATIPISCMPNAGLPVLGKDGAHYPLGPAELADAHQTFIGEFGLSLI
GGCCGTTPEHLRQVVERVRGLTPGARDPRPEPGAASLYQTVPFRQDASYLAIGERTNANG
SKKFREAMLEGRWEDCVELAREQIREGAHLLDLCVDYVGRDGAADMSELAGRLATASTLP
IVLDSTEPAVLEAGLERLGGRAVINSVNYEDGDGPDSRFAKVTRMAVEHGAALMALTIDE
RGQARTPEDKVAIAERIIADLTGNWGVAESDIIIDCLTFTICTGQEESRRDGVHTIEAIR
ELKRRHPQVQTTLGLSNISFGLNPAARLVLNSVFLDECVKAGLDSAIVHAAKILPIARIE
DEQVQVALDLIHDRRREGYDPLQRFLELFEGVDAKSMRAGKTEELLALPLEERLRRRIVD
GERKGLEADLDEALTTRPALEIVNETLLEGMKTVGELFGSGQMQLPFVLQSAEVMKTAVA
HLEPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVTAILDA
AEEHRADVIGMSGLLVKSTVIMKENLEELNQRGMAADYPVILGGAALTRAYVEQDLHEVY
QGEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKKRRVAARPAALPQEDTEEPVGRSA
TATDVPLPTAPFLGTRVIKGIPLKDYAAWLDEDALFKGQWGLKGSRSGEGPDYEELLETE
GRPRLRGWLDRLHTDNLLEAAVVYGYFPCHAEGQDLVILDEDGKERTRFTFPRQRRGRRL
CLADFFRPADSGETDVVALQAVTVGSRVSGATAELFAADAYRDYLELHGLSVQLAEALAE
FWHARVRAELGIGGSDPAALAGMFRTEYQGCRYSLGYPACPDLEDRAKIAELLQPERIGV
TLSEEFQLHPEQSTDAIVLHHPEANYFNAR
NT seq
3513 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgcccatcctgtccccgcacacccaggccgaccgcgccgccgcactgcgccgg
gccttcgcctcccgcgtcgtcgtcgccgacggcggcatgggcaccatgctccaggccgcc
gagccctccctggacgacttcgagcagctggaagggtgcaacgaggtcctgaacgtcacc
cgcccggacatcgtgcgctccgtccaccaggagtacttcgacgccggcgtggactgcgtg
gagaccaacaccttcggcgccaacctcgccgcactcggcgagtacgacatccccgaacgc
atcgccgagctctccgaggccggtgcccgcatcgcccgcgagaccgccgacgactgcgcc
gcgcgcgacggacggcagcgctgggtactgggctccatcggccccggcaccaagctgccc
accctcggccacatccgctacgccgacctgcgcgacgcgtaccagcagaacgcggagggc
ctgatcgccggcggcgccgacgccctgctggtggagaccgcccaggacctgctccagacc
aaggccgccgtgctcggcgcccgccgcgccgcggccgccaccggcgtcgacctgccgctc
gtcgtccaggtcaccgtcgagaccaccggcaccatgctgctgggctccgagatcggcgcc
gccctcaccgccctggaaccgctgggcatcgacatgatcggcctgaactgcgccaccggg
ccggccgagatgagcgagcacctgcgctatctctcccagcacgccaccatccccatctcc
tgcatgcccaacgccgggctgcccgtcctcggcaaggacggcgcccactacccgctgggc
cccgccgagctcgccgacgcccaccagaccttcatcggcgaattcggcctctccctgatc
ggcggctgctgcggcaccacccccgagcacctgcggcaggtcgtggagcgggtgcgcggg
ctgacccccggcgcgcgcgacccgcgccccgagcccggcgccgcctccctctaccagacc
gtgccgttccggcaggacgcctcctacctcgccatcggcgagcgcaccaacgcgaacggc
tccaagaagttccgcgaggccatgctggagggccgctgggaggactgcgtcgagctggcc
cgcgaacagatccgcgagggcgcccacctgctcgacctgtgcgtggactacgtcggccgc
gacggcgccgccgacatgtccgaactggccggccggctcgccaccgcctccaccctgccc
atcgtgctggactccaccgagcccgccgtcctggaggccggcctggagcggctcggcggc
cgggccgtcatcaactccgtgaactacgaggacggcgacggccccgactcgcggttcgcc
aaggtcacccggatggcggtggagcacggcgcggcactgatggccctcaccatcgacgaa
cgcggccaggcccgcacccccgaggacaaggtcgccatcgccgagcgcatcatcgccgac
ctcaccggcaactggggcgtggccgagagcgacatcatcatcgactgcctcaccttcacc
atctgcaccggccaggaggagtcccgccgcgacggggtgcacaccatcgaggccatcagg
gagctgaagcggcgccacccccaggtgcagaccaccctgggcctgtccaacatctccttc
ggcctcaacccggcggcccggctcgtcctcaactcggtcttcctcgacgaatgcgtcaag
gccggcctggactccgccatcgtgcacgccgccaagatcctgcccatcgcccggatcgag
gacgaacaggtccaggtcgccctcgacctcatccacgaccggcgccgagagggctacgac
ccgctccagcgcttcctcgaactcttcgagggcgtggacgccaagtccatgcgggccggc
aagaccgaggaactgctcgccctgcccctggaggagcggctgcgccggcgcatcgtcgac
ggcgagcgcaagggactggaggccgacctcgacgaggcgctcaccacccgccccgccctg
gagatcgtcaacgagaccctgctggagggcatgaagacggtcggcgagctgttcggttcg
ggacagatgcagctgcccttcgtgctccagtccgccgaggtcatgaagaccgccgtcgcc
cacctcgaaccgcacatggagaagtccgacgacgagggcaagggcaccatcgtgctcgcc
accgtgcgcggcgacgtccacgacatcggcaagaacctggtcgacatcatcctgtccaac
aacggctacaacgtcgtcaacctcggcatcaagcagccggtgaccgccatcctggacgcc
gccgaggaacaccgcgccgatgtcatcgggatgtccgggctgctggtgaagtccacggtg
atcatgaaggagaacctggaggagctcaaccagcgcggcatggccgccgactacccggtc
atcctcggcggcgccgccctcacccgcgcctatgtcgagcaggacctgcacgaggtctac
cagggcgaggtccgctacgcccgcgacgccttcgagggcctgcggctgatggacgccctg
atcgccgtcaagcgcggcgtgcccggcgccaccctccccgagctgaagaagcgccgggtc
gccgcccgccccgccgccctgccgcaggaggacaccgaggagccggtgggccgctcggcc
accgccaccgacgtaccgctgcccaccgccccgttcctcggcacccgcgtcatcaagggc
atcccgctcaaggactacgccgcctggctggacgaggacgccctcttcaagggccagtgg
gggctcaagggcagccgcagcggcgagggccccgactacgaggaactgctggagaccgag
ggacgcccccggctgcgcggctggctggaccggctgcacaccgacaacctcctggaggcg
gccgtcgtctacggctacttcccctgccacgccgagggccaggacctggtgatcctcgac
gaggacggcaaggaacgcacccgcttcaccttcccccgccagcgccgcggccggcggctg
tgcctggccgacttcttccgcccggcggacagcggcgagacggacgtggtcgccctgcag
gccgtcaccgtcggctcccgggtctccggcgccaccgctgaactgttcgccgccgacgcc
taccgcgactatctggagctgcacgggctgtccgtccagctcgccgaggcgctcgccgag
ttctggcacgcccgggtccgcgccgaactgggcatcggcggctccgacccggccgccctg
gccggaatgttccgcaccgagtaccagggctgccggtactccctgggctaccccgcctgc
cccgacctggaggaccgcgccaagatcgccgagctgctccagcccgagcggatcggggtc
accctgtccgaggagttccagctgcaccccgagcagtccaccgacgcgatcgtcctgcac
caccccgaggccaactacttcaacgcccgctga
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