Streptomyces sp. N50: R2B38_09680
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Entry
R2B38_09680 CDS
T11501
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
strk Streptomyces sp. N50
Pathway
strk00010
Glycolysis / Gluconeogenesis
strk00020
Citrate cycle (TCA cycle)
strk00620
Pyruvate metabolism
strk00785
Lipoic acid metabolism
strk01100
Metabolic pathways
strk01110
Biosynthesis of secondary metabolites
strk01120
Microbial metabolism in diverse environments
strk01200
Carbon metabolism
strk01210
2-Oxocarboxylic acid metabolism
Module
strk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
strk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
R2B38_09680 (aceE)
00020 Citrate cycle (TCA cycle)
R2B38_09680 (aceE)
00620 Pyruvate metabolism
R2B38_09680 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2B38_09680 (aceE)
Enzymes [BR:
strk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
R2B38_09680 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
WOX09139
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Position
2247497..2250208
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AA seq
903 aa
AA seq
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MTDPYAIQPSELDQLPDRDPEETAEWQASLDAVTKAAGPHRAAYLMRRTLERAEGNGLAL
PKLLETDYVNTIPTAAEPSAPGDEALERRITAWNRWNAAAMVTRGAKHGVGGHIATFASA
AWLYETGFNHFFKGKESAEAPGSGDQLYIQGHASPGIYARAFLDGRLTEAHLDNFRQEAG
GNGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTARGIKDVSESHVWAFLGD
GEMDEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVI
KSLWGNAWDELFQLDTTGALVRRLREVPDAQVQTYQTRGAAYIREDFFGTDPALVELAKL
LSDDKILECFHLSRGGHEANKVYAAYKAAIEHKGGPTVILAQTVKGHTLGEGFASKNANH
QMKKLSTDEFKQMRDLLELPIKDSDFIDGVVPYGHPGADSPEVRYLQERRAALGGPAPAR
RTHALAPLPSAADKTFASFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEAR
TFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTS
YATHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGH
SPVIAATNPAALSYDPAFAYEVAAIVKDGLRRMYGEAAPGEDSNVFYYLTVYNEPIPQPA
KPAGLGIDEGIVKGLYRFNTAESAGLSPAANAARIQLLGSGTAIHWALKAQRMLSEEWGV
AADVWSATSWTELRRDALDADAALLRGEERVPYVRQALQGAEGPVLAVSDYMRQVPDQIA
QWVEQDWSSLGADGFGLSDTRDAARRYFGVDAESIVVAALAQLARRGEVKATAVKEARER
YGL
NT seq
2712 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacccctacgccatccagccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgaatggcaggcctccctggacgccgtcacgaaggctgccggcccgcac
cgtgccgcgtacctgatgcgccgcacactggagcgcgcggagggcaacggcctcgcgctg
cccaagctgcttgagacggactacgtcaacaccatcccgaccgccgccgagccgtccgcg
cccggcgacgaggcgctggagcgccggatcaccgcgtggaaccgctggaacgcggcggcc
atggtgacccgtggcgcgaaacacggcgtcggcggccacatcgcgaccttcgcgtccgcg
gcctggctgtacgagaccggcttcaaccacttcttcaagggcaaggagtccgcggaagcg
cccggctccggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgc
gccttcctcgacggccgcctcaccgaggcgcacctcgacaacttccgccaggaggccggc
ggcaacggcctcccgtcgtacccgcacccccgccgcctgccctggctctgggagttcccg
acggtgtcgatgggcctcggcccgctgtcggcgatctaccaggcgcgcttcaaccgctac
ctcaccgcgcgcggcatcaaggacgtctccgagtcgcacgtctgggcgttcctcggcgac
ggcgagatggacgagccggagtcgacggcggcactcgccctggcctcccgcgagggtctg
gacaacctgaccttcgtcatcaactgcaatctccagcgcctcgacggcccggtccgcgcg
aacttcaagatcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcatc
aagtccctgtggggcaacgcctgggacgagctgttccagctcgacaccacgggcgcgctc
gtacgccgcctgcgcgaggtaccggacgcccaggtgcagacgtaccagacgcgtggcgcc
gcctacatccgcgaggacttcttcggcacggacccggcgctcgtcgagctcgcgaagctg
ctcagcgacgacaagatcctcgagtgtttccacctctcgcgcggtggtcacgaggcgaac
aaggtgtacgccgcgtacaaggcggccattgagcacaagggtggcccgacggtcatcctg
gcgcagacggtcaagggccacacgctcggcgagggcttcgcctcgaagaacgccaaccac
cagatgaagaagctgtcgacggacgagttcaagcagatgcgtgacctgctcgaactcccc
atcaaggacagcgacttcatcgacggggtcgtaccgtacggccaccccggcgccgactcc
cccgaggtccgttacctccaggagcggcgtgcggcgctcggcggaccggccccggcccgc
cgtacgcacgcgctcgctccgctgccctccgccgccgacaagacgttcgcgtccttcgac
aaggggtccggcagccagaacgtcgctacgaccatggcgttcgtacggctggtgaaggac
ctggtccgcgacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgc
acgttcggtatggagtcgctgttcccgtccctcgggatctactcccccaagggccagacg
tacgagcccgtcgaccgcgaccagctcatgtactacaaggaagccaagaacggccagatc
ctcaacgaggggatcaccgaggccggttcgatggcggacttcatcgccgcgtcgacgtcg
tacgcgacgcacggcgaagcgatgatccccttctacatcttctactcgatgttcggctgg
cagcgcacggccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctggtc
ggagcgacagcgggccgcacgaccctcacgggcgagggccttcagcacgcggacggtcac
tcccccgtgatcgcggcgacgaacccggcggcgctgtcgtacgacccggcgttcgcgtac
gaggtcgcggcgatcgtgaaggacggcctccgccggatgtacggcgaggccgccccgggt
gaggactcgaacgtcttctactacctcaccgtctacaacgagccgatcccccagcccgcc
aagccggccggcctcggtatcgacgagggcatcgtcaagggcctgtaccgcttcaacacg
gcggagtctgctgggctttcgccggctgccaacgcggcgcggatccagctcctcggctcc
ggtacggcgatccactgggcgttgaaggcgcagcggatgctctccgaggagtggggtgtg
gcggctgacgtgtggtcggcgacgtcctggaccgagctgcggcgggacgcgctggacgcg
gatgcggcgttgctgcggggcgaggagcgggtgccgtacgtgcggcaggcgctgcagggg
gccgaggggccggtgctcgccgtctccgactacatgcgtcaggttcccgaccagatcgcg
cagtgggtcgagcaggactggtcttcgctcggcgcggacggcttcggtctgtcggatacg
cgtgacgcggctcggcggtacttcggggtcgacgcggagtcgatcgtcgtggcggccctc
gcgcagctggcgcggcgtggggaagtgaaggctacggcggtcaaggaggcgcgggagcgg
tacggcttgtag
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