Streptomyces sp. N50: R2B38_11140
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Entry
R2B38_11140 CDS
T11501
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
strk Streptomyces sp. N50
Pathway
strk00010
Glycolysis / Gluconeogenesis
strk00020
Citrate cycle (TCA cycle)
strk00620
Pyruvate metabolism
strk00785
Lipoic acid metabolism
strk01100
Metabolic pathways
strk01110
Biosynthesis of secondary metabolites
strk01120
Microbial metabolism in diverse environments
strk01200
Carbon metabolism
strk01210
2-Oxocarboxylic acid metabolism
Module
strk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
strk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
R2B38_11140 (aceE)
00020 Citrate cycle (TCA cycle)
R2B38_11140 (aceE)
00620 Pyruvate metabolism
R2B38_11140 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2B38_11140 (aceE)
Enzymes [BR:
strk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
R2B38_11140 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
RL
Motif
Other DBs
NCBI-ProteinID:
WOX09400
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Position
2547308..2550055
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AA seq
915 aa
AA seq
DB search
MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDQRGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDQGDGGDQIFFQGHASPGIYARAFLLDRLSEQQLDAFRQ
EKSKAPYGLSSYPHPRSMPDFWEFPTVSMGLGPLGAIFQARMNRYMEARGIADTSRSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRTWDPLLAQDRDGVLVNQLNTTPDGQFQTYATETGAYIREHFFGHDHRLR
AMVENMTDDQILHLGRGGHDHQKVYAAFAAAKQHQGQPTVVLAQTVKGWTLGPNFEGRNA
THQMKKLTVADLKGFRDRLHLPITDQELESGAPPYFHPGRNSEEIQYMHDRRNALGGYVP
TRVVRSKPLALPEDKTYASVKKGSGQQSIATTMAFVRLLKDLMRDKEIGRRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAYSYEIAYIVQDGLRRMYGSDAEHPHGEDVFYYLTVYNEPIQH
PAEPSDVDVEGILKGVHRISRGASGTVPAQIMASGVAVPWALEAQRILAEEWNVRADVWS
ATSWNELRREAVEVERHNLLHPEEEQQVPYVTRKLSGAEGPFVAVSDWMRSVPDQISRWV
PGTYQSLGADGFGFADTRGAARRFFHIDAQSVVVAVLTELAREGKVDRSVLKQAIDRYQL
LDVASADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaatccgatcatcattggcggccttccgagtcaggttcct
gacttcgatcccgaagagacccaggagtggctcgactcgctcgacgccgccgtggaccag
cgcggccgtgagcgggcccgctatctgatgctccggctgatcgagcgggcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacacgatcgccaccaaggac
gagccgttcttccccggcaacgaggagatcgagcgcaagatcctgaacgcgacccgctgg
aacgccgcggtgatggtgtcccgggcccagcgtcccggcatcggcgtcggcggccacatc
gccacgttcgcgtcctccgcctcgctctacgacgtgggcttcaaccacttcttccggggc
aaggaccagggcgacggcggcgaccagatcttcttccaggggcacgcctcgccgggcatc
tacgcccgcgcgttcctcctggaccggctcagcgagcagcagctggacgcgttccgccag
gagaagtcgaaggcgccgtacgggctgtcctcgtacccgcacccgcggtcgatgccggac
ttctgggagttcccgaccgtgtcgatgggcctgggcccgctcggcgcgatcttccaggcg
cggatgaaccgctacatggaggcgcgcgggatcgcggacacgtcgcggtcgcacgtgtgg
gccttcctcggcgacggcgagatggacgagccggagtcgctcggccagctgtcgatcgcg
gcgcgcgagggcctggacaacctgaccttcgtcgtcaactgcaacctccagcggctcgac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgcagttccggggcgcc
ggctggaacgtcatcaagctggtctgggaccgcacctgggacccgctgctcgcccaggac
cgcgacggcgtgctggtcaaccagctcaacaccacgccggacggccagttccagacgtac
gccacggagaccggcgcgtacatccgcgagcacttcttcgggcacgaccaccggctgcgc
gcgatggtcgagaacatgaccgacgaccagatcctgcacctggggcgcggcggacacgac
caccagaaggtctacgcggccttcgcggcggccaagcagcaccagggccagccgaccgtc
gtcctcgcgcagacggtcaagggctggacgctgggccccaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgccgacctcaagggcttccgcgaccgcctccac
ctcccgatcaccgaccaggagttggagtccggcgcgccgccgtacttccacccgggccgg
aactcggaggagatccagtacatgcacgaccggcgcaacgcgctgggcggctacgtccca
acgcgtgtcgtccgctccaagccgctggccctccccgaggacaagacgtacgcgagtgtg
aagaagggttcgggccagcagtcgatcgccaccaccatggcgttcgtacgactgctcaag
gacctcatgcgggacaaggagatcggccgtcggttcgtgctgatcgcgccggacgagtac
cgcacgttcggcatggactccttcttcccgagcgcgaagatctacaacccgctgggccag
cagtacgagtcggtcgaccgtgaactcctgctcgcctacaaggagtcgccgaccgggcag
atgctgcacgacggcatctcggaggcgggctgtacggcctcgctgatcgcggcgggttcg
gcgtacgcgacacacggcgagccgctcatcccggtctacgtcttctactcgatgttcggt
ttccagcgcaccggtgaccagttctggcagatggccgaccagttggcgcgcggtttcgtg
ctgggtgcgaccgcgggtcgtacgactctgaccggcgagggactccaacacgcggacggc
cactcgcagttgctggcgtccaccaacccggggtgtgtcgcctacgacccggcgtactcg
tacgagatcgcgtacatcgtgcaggacgggctgcggcggatgtacggctcggacgcggaa
cacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagccgatccagcac
ccggccgagccgtccgatgtcgacgtggagggcatcctcaagggcgtccaccggatcagt
cggggcgcctcggggacggttccggcgcagatcatggcgtccggggtcgcggtcccgtgg
gctcttgaggcccagcggattctcgccgaggagtggaacgtccgggccgatgtgtggtcc
gcgacctcctggaacgagctgcggcgcgaggcggtcgaggtggagcggcacaacttgctg
catcccgaggaggagcagcaggttccttatgtcacgcggaagttgagcggggcggagggg
ccgttcgtggcggtttccgactggatgcggtcggttcctgaccagatctcgcggtgggtg
ccgggcacttatcagtcgttgggggctgatgggttcgggttcgcggacacgcggggggcg
gctcggcggttcttccacatcgacgcgcagtcggttgtggtggctgtgctgacggagttg
gcgcgggaggggaaggtcgatcggtccgtgttgaagcaggcgatcgatcggtatcagttg
ctggatgttgcttcggctgaccccggtgcggctggaggagatgcgtag
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