Streptomyces sp. N50: R2B38_28370
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Entry
R2B38_28370 CDS
T11501
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
strk Streptomyces sp. N50
Pathway
strk00020
Citrate cycle (TCA cycle)
strk00630
Glyoxylate and dicarboxylate metabolism
strk00785
Lipoic acid metabolism
strk01100
Metabolic pathways
strk01110
Biosynthesis of secondary metabolites
strk01120
Microbial metabolism in diverse environments
strk01200
Carbon metabolism
strk01210
2-Oxocarboxylic acid metabolism
Module
strk_M00009
Citrate cycle (TCA cycle, Krebs cycle)
strk_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
strk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
R2B38_28370
00630 Glyoxylate and dicarboxylate metabolism
R2B38_28370
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2B38_28370
Enzymes [BR:
strk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
R2B38_28370
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
R2B38_28370
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
R2B38_28370
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
R2B38_28370
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NCBI-ProteinID:
WOX12509
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Position
complement(6260492..6264319)
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AA seq
1275 aa
AA seq
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MSSQSPSNSTISTESDQAAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGAAAAPTSTSAGTAAAGAAAPTTPAPAAPAAPAPAPAAPAAPAPAAPAVPAPAPAAAAP
APVKAVAPAPAPAKAAVPAAQPKKAEPAAEASGGPEFITLRGPAAAVAKNMNASIEVPTA
TSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFQEKDGK
PTLVKPEHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLTM
DDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKV
MTLTSTYDHRVIQGAASGEFLRIVANLLLGESGFYDEIFEALRIPYEPVRWLKDIDASHD
NDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGF
AGKSLMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRIERSHSKPEREEQLRILR
RLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLN
VLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAQGTFTGLDGEQIKVTLAANPSH
LETVDPIIEGIVRARQDIINKGGTDFTVLPLALHGDAAFAGQGVVAETLNMSQLRGYRTG
GTIHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQ
AFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEA
EQALQDYQGQLEKVFTEVREATAQPGAVPMSDPQAEFPVAVNTAISSEVVKRIAESQVNI
PDNFHVHPRLLPQLQRRATMVEDGTIDWGMGETLAIGSLLLEGTPVRLSGQDSRRGTFGQ
RHAVLIDRQTGEDYTPLQYLSEEQARYNVYDSLLSEYAVMGFEYGYSLARPDALVMWEAQ
FGDFVNGAQSVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARVERFLQLCAQNN
MTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTTGQFRPVIGD
ATVTDPASVRKVVFVTGKLYYDLEAERAKRGTTDVAIIRVERLYPLPGAELQAEVNKYPN
VEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKR
HQAEQEQLVREVFEA
NT seq
3828 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtcacagtcccccagtaactcgaccatctcgaccgagtccgaccaagccgcgggt
aagaatcccgcggcggcgttcgggcccaacgagtggctcgtcgacgagatctatcagcag
tacctccaggatccgaactcggtagaccgagcctggtgggacttcttcgccgactacaag
ccgggcgcggctgccgccccgacctcgacttcggcgggtactgcggccgcgggggccgca
gcgcccaccactccagccccagcggcacccgccgccccggctccggctccggccgctcct
gccgcacccgcgcccgccgctccggcggtccccgcgccggcgcccgcagccgccgctccg
gcgccggtgaaggccgtagccccggctcccgcgcctgcgaaggcggcggtcccggccgct
cagccgaagaaggcggagcccgcggccgaggcctccggtggcccggagttcatcacgctg
cgcggtcccgccgccgcggtcgcgaagaacatgaacgcgtcgatcgaggtccccaccgcc
acgtcggtgcgcgcggtcccggtcaagctgctcttcgacaaccgcatcgtcatcaacaac
cacctgaagcgcgcccggggcgggaagatctccttcacccacctcatcggctacgcgatg
gtgcaggccatcaaggccatgccgtcgatgaactactccttccaggagaaggacggcaag
ccgaccctggtcaagccggagcacgtgaacttcggtctcgccatcgacctggtgaagccg
aacggcgaccgccagctcgtcgtcgccggcatcaagaaggccgagacgctgaacttcttc
gagttctggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaagctgacgatg
gatgacttcacgggcgtcaccgtgtcgttgaccaaccccggcggcctcggcaccgtccac
tcggtcccccgcctgatgcccggtcagtcggtcatcatgggcgtcggctcgatggactac
ccggcggagttccagggcaccagccaggacaccctgaacaagctcggcatctcgaaggtc
atgacgctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttc
ctgcggatcgtcgcgaacctcctgctcggcgagagcggcttctacgacgagatcttcgag
gcgctgcgcatcccgtacgagccggtccgctggctcaaggacatcgacgcgtcgcacgac
aacgacgtgacgaaggccgcccgcgtcttcgagctgatccactcctaccgggtccgcggc
cacgtcatggccgacaccgacccgttggagtaccgccagcgcaagcaccccgacctggac
atcaccgagcatggtctgacgctctgggacctggagcgggagttcgcggtcggcggcttc
gccggcaagtccctgatgaagctgcgcgacatcctgggcgtgctgcgcgactcgtactgc
cgcaccaccggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggatccag
gaccgcatcgagcgctcgcactccaagccggagcgcgaggagcagctgcgcatcctgcgc
cgcctgaacgcggcggaggccttcgagaccttcctgcagacgaagtacgtcggccagaag
cgcttctcgctcgaaggcggcgagtcggtcatcccgctcctcgacgcggtcatcgacagc
gcggccgagtcgcgcctcgacgaggtcgtcatcggcatggcccaccgcggccgcctgaac
gtgctcgcgaacatcgtcggcaagtcgtacgcccagatcttccgcgagttcgagggcaac
ctcgacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgcccagggc
accttcaccggcctggacggcgagcagatcaaggtcaccctcgcggcgaacccgtcccac
ctggagacggtcgacccgatcatcgagggcatcgtccgcgcccgccaggacatcatcaac
aagggcggcacggacttcacggtcctcccgctggccctgcacggtgacgcggccttcgcg
ggccagggcgtggtcgccgagacgctcaacatgtcgcagctgcgcggctaccgcaccggc
ggcacgatccacatcgtcatcaacaaccaggtcggcttcacggccgctccggagtcctcg
cgttcttccatgtacgcgacggacgtggcgaggatgatcgaggccccgatcttccacgtg
aacggcgacgacccggaggcagtggtccgcgtcgcgcgcctggccttcgagttccgtcag
gcgttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaacgag
tcggacaacccggccttcacccagcccctgatgtacgacctgatcgacaagaagcgctcg
gtgcgcaagctgtacaccgagtcgctgatcggtcgcggcgacatcacccttgaggaagcc
gaacaagccctccaggactaccagggccagctggagaaggtcttcacggaggtccgcgag
gcgacggcccagcccggtgccgttcccatgtcggacccgcaggcggagttcccggtcgcg
gtcaacacggcgatctcctccgaggtcgtcaagcgcatcgccgagtcccaggtcaacatc
ccggacaacttccacgtccacccgcgcctgctgccccagctgcagcgccgggcgacgatg
gtcgaggacgggacgatcgactggggcatgggcgagacgctggcgatcggttcgctgctg
ctggagggcaccccggtacgcctctccggccaggactcccgccgcggcacgttcggccag
cgccacgcggtcctcatcgaccggcagacgggcgaggactacaccccgctccagtacctc
tccgaggagcaggcgcgctacaacgtctacgactcgctcctctccgagtacgcggtcatg
ggcttcgagtacggctactcgctcgcccgtcccgacgcgctcgtgatgtgggaggcgcag
ttcggcgacttcgtcaacggcgcgcagtccgtggtcgacgagtacatctcggcggcggag
cagaagtggggccagacgtccggcgtcacgctcctgctcccgcacggctacgagggccag
ggcccggaccactcctcggcccgggtggagcgcttcctgcagctctgcgcgcagaacaac
atgacggtcgcgatgccgaccctcccgtcgaactacttccacctcctgcggtggcaggtg
cacaacccgcaccacaagccgctggtggtcttcaccccgaagtcgatgctgcgcctgaag
gccgccgcgtcgaagacggaggagttcacgacgggtcagttccgcccggtcatcggcgac
gcgacggtgacggaccccgcgtccgtccgcaaggtcgtcttcgtcaccggcaagctctac
tacgaccttgaggccgagcgcgccaagcgcggcaccacggacgtggcgatcatccgcgtc
gagcgcctgtacccgctgccgggtgcggagctccaggcggaggtcaacaagtacccgaac
gtcgagaagtacctgtgggcccaggaggagccggcgaaccagggtgcctggcccttcatc
gccctcaacctgatcgaccacctggacctcgcggtcggcgcggacgtgccccacggcgag
cgactgcggcgcatctcgcgcccgcacagctcgtcgccggcggtgggttccgcgaagcgt
caccaggccgagcaggagcagttggtgcgggaggtcttcgaggcgtaa
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