Streptomyces sp. RLB1-33: HEP84_18090
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Entry
HEP84_18090 CDS
T10398
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
strl Streptomyces sp. RLB1-33
Pathway
strl00010
Glycolysis / Gluconeogenesis
strl00020
Citrate cycle (TCA cycle)
strl00620
Pyruvate metabolism
strl00785
Lipoic acid metabolism
strl01100
Metabolic pathways
strl01110
Biosynthesis of secondary metabolites
strl01120
Microbial metabolism in diverse environments
strl01200
Carbon metabolism
strl01210
2-Oxocarboxylic acid metabolism
Module
strl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
strl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HEP84_18090 (aceE)
00020 Citrate cycle (TCA cycle)
HEP84_18090 (aceE)
00620 Pyruvate metabolism
HEP84_18090 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HEP84_18090 (aceE)
Enzymes [BR:
strl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HEP84_18090 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
RL
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QIY70814
UniProt:
A0A6H1L7L3
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Position
3974666..3977413
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AA seq
915 aa
AA seq
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MVSGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAFLLDRLSEQQLDAFRQ
EKSKAPYGLSSYPHPRLMPGFWEFPTVSMGLGPLGAIFQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRTWDPLLAQDRDGVLVNKLNTTPDGQFQTYATETGDYIRRHFFGDDHRLR
AMVENMTDDQILHLGRGGHDHKKIFAAFSAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVADLKGFRDRLHLPISDKELESGAPPYYHPGRNSEEIQYMHDRRKGLGGYVP
TRVVRSQPLALPDDKAYASVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGFEIAHIVKDGLRRMYGSSDEHPHGEDVFYYLTVYNEPIQH
PAEPADVDVDGILKGIHRYAEGTSGSVPAQILASGVAVPWAVEAQRILAEEWNVRADVWS
ATSWNELRREAVDVERHNLLHPEEEQRVPYVTQKLSGAEGPFVAVSDWMRSVPDQISRWV
PGTYQSLGADGFGFADTRGAARRFFHIDAQSIVVAVLTELAREGKVDRSVLKQAIDRYQL
LDVASADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggtttccggatccgatcgcaatccgatcatcattggcggccttcccagtcaggtcccg
gacttcgaccccgaagagacccaggagtggctcgactccctcgacgccgccgtcgacgag
cgcggccgtgagcgcgcccgctatctgatgctgcggctgatcgaaagggcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacacgatcgccaccaaggac
gagcccttcttccccggcaacgaggagatcgagcgcaaggtcctcaacgccacccgctgg
aacgcggccgtgatggtctcgcgcgcccagcgtcccggcatcggcgtcggcggccacatc
gccaccttcgcctcctccgcctcgctctacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccaggggcacgcctcccccggtatc
tacgcccgcgcgttcctcctcgaccggctctccgagcagcagctcgacgcgttccggcag
gagaagtcgaaggctccgtacggtctgtcctcgtacccgcacccgcgcctgatgccgggc
ttctgggagttcccgaccgtctccatgggcctcggtccgctcggcgcgatcttccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgcggacacctccaagtcacacgtctgg
gcgttcctcggggacggcgagatggacgagccggaatcgctcggacagctgtccatcgcc
gctcgagagggcctggacaacctgaccttcgtcgtcaactgcaacctccagcgcctcgac
ggcccggtacgcggcaacggaaagatcatccaggagctggagtcccagttccggggcgcc
ggctggaacgtcatcaagctggtctgggaccgcacctgggacccgctgctcgcgcaagac
cgcgacggcgtgctggtcaacaagctgaacaccaccccggacggccagttccagacgtac
gccaccgagacgggcgactacatccgccggcacttcttcggtgacgaccaccggctgcgg
gcgatggtcgagaacatgaccgacgaccagatcctgcacctggggcgcggcggtcacgac
cacaagaagatcttcgcggcgttctcggcggccaaggcgcacaagggccagccgacggtg
atcctggcgcagacggtcaagggctggacgctcggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgccgacctcaagggcttccgggaccgtctgcac
ctgccgatctccgacaaggagctggagtccggcgcgccgccgtactaccacccgggccgc
aactcggaagagatccagtacatgcacgaccgccgcaaggggctcggcggatacgtcccc
acgcgcgtcgtacggtcgcagccgctggccctgccggacgacaaggcgtacgcgagtgtg
aagaagggctccggtcagcagtcgatcgccacgaccatggcgttcgtgcgactgctgaag
gacctcatgcgggacaaggagatcggcaagcggttcgtgctgatcgcgcccgacgagtac
cgcacgttcggcatggactcgttcttcccgagcgcgaagatctacaacccgctcggccag
cagtacgagtccgtggaccgcgatctgctcctggcctacaaggagtcgccgaccggtcag
atgctgcacgacggcatctccgaggcgggctgcacggcctcgctgatcgccgcgggttcg
gcgtacgccacgcacggcgagccgctgatcccggtctacgtcttctactcgatgttcggt
ttccagcgcaccggtgaccagttctggcagatggccgaccagttggcgcgcggtttcgtc
ctgggcgcgaccgccggccgtacgactctgaccggtgagggccttcagcacgcggacggc
cactcgcagctgctcgcctcgaccaacccgggctgtgtcgcgtacgacccggcgttcggg
ttcgagatcgcgcacatcgtcaaggacggtctacgccggatgtacggctcgtccgacgaa
cacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagccgatccagcac
ccggccgagcccgcggacgtcgacgtcgacggcatcctcaagggcatccaccgctacgcg
gaagggacttcgggttccgtcccggcgcagatcctggcgtccggtgtcgccgtgccgtgg
gcggtcgaggcgcagcggatcctcgccgaggagtggaacgtacgcgccgacgtctggtcg
gcgacctcctggaacgagctgcggcgcgaggccgtcgacgtggagcggcacaatctgctg
caccccgaggaggagcagcgcgtcccctatgtgacgcagaagctgagcggcgccgagggt
ccgttcgtggccgtctccgactggatgcgatcggttccggaccagatctcgcgatgggtg
ccgggcacgtaccagtcgctcggcgcggacggcttcggcttcgcggacacgcgcggcgcg
gcccggcgcttcttccacatcgacgcgcagtcgatcgtggtcgcggtgctgaccgagctg
gcccgtgagggcaaggtcgaccggtcggtgctgaagcaggcgatcgaccgctatcagctg
ctcgacgtggcgtcggccgacccgggagccgcgggcggcgacgcgtag
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