Streptomyces sp. PAMC 26508: F750_1305
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Entry
F750_1305 CDS
T02619
Symbol
whiE-KS
Name
(GenBank) polyketide beta-ketoacyl synthase WhiE-KS
KO
K05551
minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
strp
Streptomyces sp. PAMC 26508
Pathway
strp00253
Tetracycline biosynthesis
strp01056
Biosynthesis of type II polyketide backbone
strp01100
Metabolic pathways
strp01110
Biosynthesis of secondary metabolites
Module
strp_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
strp00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
F750_1305 (whiE-KS)
00253 Tetracycline biosynthesis
F750_1305 (whiE-KS)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
strp01004
]
F750_1305 (whiE-KS)
01008 Polyketide biosynthesis proteins [BR:
strp01008
]
F750_1305 (whiE-KS)
Enzymes [BR:
strp01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
F750_1305 (whiE-KS)
2.3.1.260 tetracycline polyketide synthase
F750_1305 (whiE-KS)
Lipid biosynthesis proteins [BR:
strp01004
]
Polyketide synthase
Component type
F750_1305 (whiE-KS)
Polyketide biosynthesis proteins [BR:
strp01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
F750_1305 (whiE-KS)
Nonaketide PKS
F750_1305 (whiE-KS)
Decaketide PKS
F750_1305 (whiE-KS)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
AGJ53813
LinkDB
All DBs
Position
1322785..1324056
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AA seq
423 aa
AA seq
DB search
MNRRVAVTGIGVVAPGGTGTKEFWSLITSGRTATGPLTAFDATPYRSRIAAQCAFDPLAA
GFSPREVRRLDRAALFAVACAREALADAGLASGTPPVPERTGVSLGTAVGCTTSLENEYA
VVSDGGRDWLVDHRHAVPQLVDYLVPSSLAREVAWAADALGPAAVISAGCTSGLDAVGHA
CEIIREGTADVMLTGGTDAPISPITVASFDAIRATSARNDDPATASRPFDRTRDGFVLGE
GAAVLVLEEWSHAVGRGAHVYAEIGGHASRGNAYHMTGLRPDGREMAEAITRALDEARLD
PTAVDYVNAHGSGTLQNDRHESAAFLRALGEHARGIPVSSIKSMIGHSLGAIGAIEIAAC
ALALEHGVVPPTANLHEPDPDCPLDYVPVTAREQRLDAVLTVGSGFGGFQSAMVLTRPEG
TRR
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
gtgaaccgcagggtcgccgtcaccggaatcggcgtggtcgcacccggcggcaccgggacg
aaggagttctggtcactgatcacttccggccggaccgcgacgggccccctgacggccttc
gacgcgacgccctaccgttcgcgcatcgccgcgcagtgcgccttcgacccgctggccgcc
ggcttctccccgcgtgaggtccgcagactggaccgcgcggccctgttcgccgtggcctgc
gcccgggaggcgctcgcggacgccgggctcgcgtcaggcactcccccggtgcccgagcgg
accggtgtgtccctgggcaccgcggtcggctgcacgacgagcctggagaacgagtacgcc
gtcgtcagcgacggcggccgcgactggctcgtggaccaccgccacgccgtgccgcagctg
gtggactacctcgtccccagcagcctggcccgggaggtggcgtgggcggcggacgccctc
ggtcccgccgcggtgatctcggccggctgcacgtccgggctcgacgccgtggggcacgcc
tgcgagatcatccgcgagggcaccgccgacgtcatgctcaccggcgggaccgacgcgccg
atctcccccatcaccgtcgcctccttcgacgccatcagggcgacctccgcgcgcaacgac
gacccggcgaccgcctcgcggccgttcgaccgtacccgggacggcttcgtcctgggtgag
ggcgccgccgtgctggtgctggaggagtggtcgcacgccgtgggccggggtgcgcacgtc
tacgccgagataggcggtcacgcctcgcgcggcaacgcctaccacatgacgggtctgcgg
ccggacggccgggagatggcggaggcgatcacccgggccctcgacgaggcccggctggac
ccgaccgcggtcgactacgtcaacgcgcacggctccggaacgctgcagaacgaccggcac
gagtcggccgccttcctgcgcgcgctcggcgagcacgcccggggcattcccgtcagctcc
atcaagtcgatgatcggccactcgctcggcgcgatcggggccatagagatcgcggcgtgc
gccctcgccctggagcacggagtcgtgcctcccaccgccaacctccacgaaccggacccc
gactgcccgctcgactacgtgccggtcaccgccagggagcagcgcctggacgccgtcctc
acggtgggcagcggtttcggcggcttccagagcgccatggtgctcacccggcccgaaggg
acacgccgatga
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