KEGG   Streptomyces sp. PAMC 26508: F750_1455
Entry
F750_1455         CDS       T02619                                 
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
strp  Streptomyces sp. PAMC 26508
Pathway
strp00270  Cysteine and methionine metabolism
strp00450  Selenocompound metabolism
strp00670  One carbon pool by folate
strp01100  Metabolic pathways
strp01110  Biosynthesis of secondary metabolites
strp01230  Biosynthesis of amino acids
strp04980  Cobalamin transport and metabolism
strp04981  Folate transport and metabolism
Module
strp_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:strp00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    F750_1455
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    F750_1455
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    F750_1455
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    F750_1455
   04980 Cobalamin transport and metabolism
    F750_1455
Enzymes [BR:strp01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     F750_1455
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2 DUF2497
Other DBs
NCBI-ProteinID: AGJ53955
LinkDB
Position
complement(1468362..1471874)
AA seq 1170 aa
MASLPTPSADSRTRAAALREALATRVVVADGAMGTMLQAQDPTLEDFENLEGCNEILNVT
RPDIVRSVHEEYFAVGVDCVETNTFGANASALGEYDIPGRIHELSEAGARIARETADRFT
ESTGQQRWVLGSIGPGTKLPTLGHAPYTVLRDGFQQNAEGLIAGGADALIIETTQDLLQT
KAAVLGARRALEAMGSDLLVLCSLAFETTGTMLLGSEIGAALTALEPLGVDMIGLNCSTG
PAEMSEHLRYLTRHSRIPLLCMPNAGLPVLTKDGAHFPLDAEGLADAQETFVQEYGLSLV
GGCCGTTPEHLRRLVERVRGAALSTRDPRPEPGAASLYQTIPFRQDTSYLAIGERTNANG
SKKFREAMLDARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTLP
IVLDSTEVPVLRAGLEKLGGRAVLNSVNYEDGDGPESRFAKVAGLAAEHGAALIALTIDE
EGQARTVEHKVAIAERLIEDLTTNWGIRESDILIDCLTFTICTGQEESRKDGIATIGAIR
ELKRRRPDVQTTLGLSNISFGLNPAARVVLNSVFLDECVKAGLDSAIVHASKILPIARLE
EEQVKVALDLIHDRREEGYDPLQRLMELFEGVNMKSMKQGKAEELLALPLDERLQRRIID
GEKNGLEADLDEALLTTPALEIVNDTLLAGMKVVGELFGSGQMQLPFVLQSAEVMKSAVA
HLEPHMEKTDAEGKGTIVLATVRGDVHDIGKNLVDIILSNNGFNVVNLGIKQPVSAILDA
AQEHRADVIGMSGLLVKSTVIMKENLEELNQRKLAADYPVILGGAALTRAYVEQDLHEIY
EGEVRYARDAFEGLRLMDALVAVKRGVPGAALPELKQRRVPKRDTPVAEAVEPEEGVRSD
VSVTNPVPEPPFWGTRVIKGIQLKEYASWLDEGALFKGQWGLKQARAGDGPTYEELVERE
GRPHLRGWLDKLHTENLLEAAVVYGYFPCVSKGDDLILLHEDGSERTRFTFPRQRRGRRL
CLADFFRPEESGETDVIGLQVVTVGSKIGGATAELFEANSYRDYLELHGLSVQLAEALAE
YWHARVRSELGFAGEDPSDVEDMFALKYRGARFSLGYGACPDLEDRAKIAALLEPERIGV
KLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggcctcgttgccgaccccctcagctgacagccggacccgagccgcagcgctccgtgag
gcgctcgccacccgggtggtggtggccgacggtgccatgggcaccatgctccaggcccag
gaccccacccttgaggacttcgagaacctcgaaggctgcaacgagatcctgaacgtcacg
cgccccgacatcgtccggtcggtccacgaggagtacttcgcggtcggcgtggactgcgtc
gagaccaacacgttcggagccaacgcctccgccctcggcgagtacgacatccccggccgg
atccacgagctgtccgaggccggcgcgcgcatcgcccgcgagaccgccgaccggttcacc
gagtccaccgggcagcagcgctgggtgctcggctccatcggccccggcaccaagctcccg
acactggggcacgccccctacacggtcctgcgcgacggtttccagcagaacgccgagggc
ctgatcgcgggcggcgccgacgcgctcatcatcgagaccacgcaggacctcctgcagacc
aaggccgccgtgctcggcgcgcggcgggccctggaggccatgggcagcgacctcctggtg
ctctgctcgctggccttcgagacgaccggcaccatgctgctgggctccgagatcggcgcg
gcgctgaccgcgctcgaacccctcggcgtcgacatgatcgggctcaactgctcgaccggc
cccgccgagatgagcgagcacctgcgctacctcacgcgccactcccgcatcccgctgctc
tgcatgccgaacgccgggctgcccgtgctcaccaaggacggcgcgcacttcccgctcgac
gccgaaggcctggccgacgcccaggagaccttcgtccaggagtacggcctctccctcgtg
ggcggctgctgcggtacgacgccggaacacctgcgccggctcgtcgagcgggtccgcggc
gccgcgctgtcgacgcgcgacccccgccccgagccgggtgccgcgtcgctctaccagacc
atcccgttccggcaggacacctcgtacctcgcgatcggcgaacgcacgaacgccaacgga
tccaagaagttccgcgaggccatgctcgacgcccgctgggacgactgcgtggagatggcc
cgggaccagatccgcgaaggcgcgcacatgctcgacctctgcgtcgactacgtggggcgc
gacggcgtcgccgacatggaggaactggccggccgtttcgccaccgcctcgaccctgccg
atcgtcctcgactccaccgaggtccccgtcctgcgcgcaggcctggagaagctgggcgga
cgcgccgtactgaactccgtcaactacgaggacggtgacggtcccgagtcccgcttcgcg
aaggtcgccgggctcgccgccgagcacggcgccgcgctcatcgcgctgaccatcgacgag
gagggccaggcccgcaccgtcgagcacaaggtcgccatcgccgagcggctcatcgaggac
ctcaccaccaactggggcatccgcgagtcggacatcctcatcgactgcctgaccttcacc
atctgtaccggtcaggaggagtcccgcaaggacgggatcgccaccatcggcgccatccgc
gagctgaagcggcgccgccccgacgtccagaccacgctgggcctgtccaacatctccttc
ggcctgaaccccgccgcccgcgtcgtcctgaactccgtcttcctcgacgagtgcgtgaag
gccggcctggactccgcgatcgtccacgcctccaagatcctcccgatcgcccggctggag
gaggagcaggtcaaggtcgccctcgacctcatccacgaccgccgcgaggagggctacgac
cccctccagcggctcatggagctcttcgagggcgtcaacatgaagtcgatgaagcagggc
aaggccgaggaactcctcgccctgccgctggacgagcggctccagcgccgcatcatcgac
ggcgagaagaacggcctggaggcggacctcgacgaggcgctgctgaccacacccgcgctg
gagatcgtcaacgacacgctgctggccggcatgaaggtcgtgggtgaactgttcggctcc
ggccagatgcagcttcccttcgtgctccagtccgccgaggtcatgaagtccgcggtggcg
cacctcgaaccgcacatggagaagaccgacgccgagggcaagggcaccatcgtgctggcc
acggtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctgtccaac
aacggcttcaacgtggtcaacctgggcatcaagcagcccgtctccgcgatcctggacgcc
gcccaggagcaccgcgccgacgtcatcggcatgtcgggcctcctggtgaagtccaccgtg
atcatgaaggagaacctggaggagctgaaccagcgcaagctggcggccgactatccggtg
atcctcggcggggcggccctgacccgtgcctacgtcgaacaggacctccacgagatctac
gagggcgaggtccgttacgcccgcgacgccttcgaggggctccggctgatggacgccctc
gtcgcggtcaagcgcggtgtccccggcgccgccctccccgaactgaagcagcgcagggtg
cccaagcgggacacccccgtcgcggaggccgtggagcccgaggagggcgtgcgctccgac
gtctccgtcaccaatccggtcccggagccgcccttctggggcacccgcgtcatcaagggc
atccagctcaaggagtacgcctcctggctggacgagggagcactcttcaagggccagtgg
ggcctcaagcaggcccgggccggcgacgggccgacgtacgaggaactggtggagcgcgag
ggccgtccgcacctgcgcggctggctcgacaagctgcacaccgagaacctgctggaggcc
gccgtcgtctacggctacttcccctgcgtctccaagggcgacgacctgatcctgctgcac
gaggacggttccgagcgcacccgcttcaccttcccgcgccagcgtcgcggccgccgcctc
tgcctcgcggacttcttccgccccgaggagtccggggagaccgacgtgatcggtctccag
gtcgtcaccgtcggatcgaagatcggcggggccaccgccgagctgttcgaggcgaactcc
taccgcgactacctggagctgcacgggctctccgtgcagctcgccgaggcactcgccgag
tactggcacgcccgggtccgcagcgagctcgggttcgccggcgaggacccgtccgacgtc
gaggacatgttcgcgctcaagtaccgcggggcgcgcttctcgctgggctacggggcctgc
ccggacctggaggaccgggcgaagatcgccgccctcctggagcccgagcggatcggggtg
aagctctccgaggagttccagctgcatcccgaacagtccacggacgccatcgtcatccac
cacccggaggcgaagtacttcaacgcacggtag

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