Streptomyces sp. PAMC 26508: F750_4808
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Entry
F750_4808 CDS
T02619
Name
(GenBank) dihydrolipoamide succinyltransferase component (E2)
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
strp
Streptomyces sp. PAMC 26508
Pathway
strp00020
Citrate cycle (TCA cycle)
strp00630
Glyoxylate and dicarboxylate metabolism
strp00785
Lipoic acid metabolism
strp01100
Metabolic pathways
strp01110
Biosynthesis of secondary metabolites
strp01120
Microbial metabolism in diverse environments
strp01200
Carbon metabolism
strp01210
2-Oxocarboxylic acid metabolism
Module
strp_M00009
Citrate cycle (TCA cycle, Krebs cycle)
strp_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
strp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
F750_4808
00630 Glyoxylate and dicarboxylate metabolism
F750_4808
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F750_4808
Enzymes [BR:
strp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
F750_4808
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
F750_4808
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
F750_4808
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
F750_4808
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
2-oxoacid_dh
OxoGdeHyase_C
2-oxogl_dehyd_N
Trypco1
Motif
Other DBs
NCBI-ProteinID:
AGJ57247
LinkDB
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Position
complement(4980103..4983903)
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AA seq
1266 aa
AA seq
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MSSQSPSNSSISTDQEAGSGSNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGTSGTADKPVPAPTGAVTPAPAATNGATAQAPAAPQAAPAAPAAAAPAAPAAPAKAAPA
APAKAAPAKAAPAAAKADASTEAPAGPEYVTLRGPSAAVAKNMNASLELPTATSVRAVPV
KLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMNYSFAVKDGKPTLVKPEH
VNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARVGKLGMDDFSGVTA
SLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNKLGISKVMTLTSTYD
HRVIQGAASGEFLRVLAQLLLGENDFYDEIFKALRIPYEPVRWLKDIDASHDDDVTKAAR
VFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLERDFAVGGFAGKTMMKL
RDILGVLRESYCRTTGIEFMHIQEPKERKWLQDRVERPRPAPEREEQLRILRRLNAAEAF
ETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMAHRGRLNVLANIVGK
SYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEAVDPVL
EGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVIN
NQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLAFEYRQTFNKDVVI
DLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQ
GQLEKVFAEVREATSAPSQPHVPDVQAEFPVSVGTAVSSEVVKLIAESQVNIPDGITVHP
RLLPQMQRRAASVDNGTIDWGMGETLAIGSLLMEGTPVRLAGQDTRRGTFGQRHAVLVDQ
KTGEDYTPLLYLSEDQARYNVYDSLLSEYAAMGFEYGYSLARPESLVIWEAQFGDFVNGA
QTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNMTVAMPTL
PSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKVEEFTTGGFRPVIGDETVGAEAV
RKVVFVSGKLYYDLDAEREKRGDTETAIIRLERLYPLPGAEIQAEIAKYPNAEKYLWAQE
EPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQTQLV
NEVFEA
NT seq
3801 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagcatctcgaccgatcaagaagcgggctccggg
tccaacccggccgccgctttcggccccaatgagtggctcgtcgacgagatctaccagcag
tacctccaggaccccaactcggtcgaccgcgcctggtgggacttcttcgccgactacaag
ccgggtacgtccggcacggcggacaagcccgtccccgcacccacgggagcggtgaccccg
gccccggccgcgaccaacggcgccacggcacaggctccggccgcgccgcaggcggccccg
gccgcacccgcggccgccgctccggcggctccggccgccccggcgaaggccgctcccgcc
gctcccgccaaggcggcacccgcgaaggcggccccggccgccgcgaaggctgacgcctcg
accgaggccccggccggccccgagtacgtgacgctgcgcggcccgtcggccgccgtcgcg
aagaacatgaacgcctccctggagctgccgacggccacgtcggtccgcgccgtgccggtg
aagctgctcttcgacaaccgcatcgtcatcaacaaccacctgaagcgggcccgtggcggg
aagatctccttcacgcacctcatcgggtacgcgatggtgcaggccctcaaggccatgccg
tcgatgaactactccttcgcggtgaaggacggcaagccgaccctggtcaagccggagcac
gtgaacctcggcctcgccatcgacctggtgaagccgaacggcgaccgtcagctcgtcgtc
gcggccatcaagaaggccgagaccctcaacttcttcgagttctggcaggcctacgaggac
atcgtccgccgtgcccgcgtcggcaagctcggcatggacgacttctccggggtcaccgcc
tcgctgacgaaccccggcggcatcggcaccgtgcactcggtgccccgcctgatgcccgga
cagggcctcatcatgggtgtcggcgccatggactaccccgcggagttccagggcacctcc
caggacaccctgaacaagctgggtatctcgaaggtcatgaccctgacctcgacgtacgac
caccgggtcatccagggtgccgcgtccggcgagttcctccgcgtcctggcccagctgctg
ctcggcgagaacgacttctacgacgagatcttcaaggcgctgcgcatcccctacgagccg
gtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcgcgg
gtcttcgagctgatccactcctaccgggtccgcggtcacgtgatggccgacaccgacccg
ctggagtaccgccagcgcaagcaccccgacctggacatcaccgagcacggcctcaccctg
tgggacctggagcgcgacttcgcggtcggcggtttcgccggcaagacgatgatgaagctc
cgcgacatcctcggcgtcctgcgtgagtcgtactgccgcaccaccggcatcgagttcatg
cacatccaggagccgaaggagcgcaagtggctccaggaccgggtggagcgtccgcgcccc
gctccggagcgcgaggagcagctgcggatcctgcgccgcctcaacgccgccgaggcgttc
gagacgttcctgcagaccaagtacgtcggccagaagcgcttctcgctggagggcggcgag
tccgtcatcccgctgctcgacgcggtcatcgactccgccgccgaggcccgcctcgacgag
gtcgtcatcggcatggcccaccgcggccggctgaacgtcctggcgaacatcgtgggcaag
tcgtacgcacagatcttccgggagttcgagggcaacctcgacccgcggtcgatgcacggc
tccggcgacgtcaagtaccacctgggcgccgagggcaccttcaccggtctggacggcgag
cagatcaaggtctcgctggccgccaacccctcgcacctggaggccgtcgacccggtcctc
gagggcatcgcgcgcgccaagcaggacatcatcaacaagggcggcacggacttcacggtc
ctgcccgtcgcgctccacggcgacgcggccttcgcgggccagggcgtcgtcgccgagacg
ctcaacatgtcgcagctgcgcggctaccgcaccggcggcaccgtgcacgtggtgatcaac
aaccaggtcggcttcaccgccgccccggagtcctctcgctcctcgatgtacgccacggac
gtggcgcgcatgatcgaggcgccgatcatccacgtcaacggcgacgacccggaggccgtg
gtccgcgtcgcgcggctcgccttcgagtaccggcagacgttcaacaaggacgtcgtgatc
gacctcatctgctaccgccgccgcggtcacaacgagggcgacaacccggagttcaccaac
ccgcagatgtacaccctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtcc
ctcatcggtcgtggcgacatcacgctggaagaggccgaacaggcgctccaggacttccag
gggcagctggagaaggtcttcgccgaggtccgcgaggccacctccgcaccgtcccagccg
cacgtcccggacgtccaggcggagttcccggtctcggtcggcaccgcggtgtcctccgag
gtcgtgaagctgatcgccgagtcgcaggtcaacatccccgacggcatcacggtgcacccg
cgtctgctgccgcagatgcagcgccgcgcggcctcggtggacaacggcacgatcgactgg
ggcatgggcgagaccctggccatcggttcgctgctgatggagggcaccccggtccggctc
gccggccaggacacccgccgcggcacgttcggtcagcgtcacgccgtcctcgtcgaccag
aagaccggcgaggactacaccccgctgctctacctctccgaggaccaggcccgttacaac
gtctacgactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcgctg
gcccgcccggagtccctggtgatctgggaggcccagttcggtgacttcgtcaacggcgcc
cagaccgtcgtggacgagttcatctcctccgccgagcagaagtggggccagacgtccggc
gtcaccctgctgctcccgcacggctacgagggccagggcccggaccactcgtccgcgcgc
ccggagcgcttcctgcagatgtgcgcgcaggacaacatgacggtcgcgatgccgaccctc
ccgtcgaactacttccaccttctgcgctggcaggtgcacaacccgcaccacaagccgctg
atcgtcttcaccccgaagtcgatgctgcgtctcaaggccgccgcctcgaaggtcgaggag
ttcaccaccggcggcttccgcccggtgatcggcgacgagacggtcggcgccgaggcggtc
cgcaaggtcgtgttcgtgtccgggaagctctactacgacctggacgccgagcgcgagaag
cgcggcgacacggagacggcgatcatccggctggagcgtctgtacccgctgccgggtgcg
gagatccaggccgagatcgccaagtacccgaacgccgagaagtacctctgggcccaggag
gagccggcgaaccagggtgcgtggccgttcatcgcgctcaacctgatcgaccacctggac
ctggccgtcggcgccgacgtgccgcacggtgagcgcctgcgccgcatctcgcgtccgcac
ggctcgtccccggcggtcggctcggccaagcgtcaccaggcggagcagacccagctggtc
aacgaggtcttcgaggcctga
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