Streptomyces sp. PAMC 26508: F750_6225
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Entry
F750_6225 CDS
T02619
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
strp
Streptomyces sp. PAMC 26508
Pathway
strp00909
Sesquiterpenoid and triterpenoid biosynthesis
strp01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
strp00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
F750_6225
Enzymes [BR:
strp01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
F750_6225
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
F750_6225
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
AGJ58652
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Position
6636783..6638795
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AA seq
670 aa
AA seq
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MTATTDGSTGAANLRAAAASDPTESTSAAPDMMAVARHAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVKAAARFIRGEQLGDGTWNTFYEGPPDLSATVEAY
VALRLAGDRPDDPHMIRAAGWVREQGGIAESRVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFTLDELHTDPACPNPSRPTAPAASW
DGVFQRLDKALHLYHKVAPRRLRRIAMNEAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVSPDHPAL
VRAADWMLGEEIVRPGDWAVRKPGLAPGGWAFEFHNVNYPDIDDTAEVALALRRVRHPDP
ARVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAHDPRTRRGVEWLLAEQEASGAWFGRWGVNYIYGTGSVVPALIAAGLPAAHP
SVRRAVDWLRSVQNDDGGWGEDLRSYREEKWIGHGSSTASQTGWALLALLAAGERETRSV
ERGVAWLAATQQADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFATAT
AIGAGTGKGA
NT seq
2013 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggggccgcgaacctccgcgcggcagcggcgagc
gatccgaccgaatcgaccagtgccgcgcccgacatgatggccgtggcgcggcacgccgcg
gagcgctcggtggagcacctcctcggcaggcaggacgagcagggctggtggaagggcgac
ctcgccaccaacgtcaccatggacgcggaggacctgctgctccgtcagttcctgggcatc
caggacccggagaccgtcaaggccgcggcccgcttcatccggggcgagcaactcggcgac
ggtacctggaacaccttctacgaggggcctcccgacctctccgccaccgtcgaggcgtac
gtcgcgctgcggctggccggggaccggcccgacgacccccatatgatccgcgcggccggc
tgggtcagggaacagggcggcatcgcggaatcccgggtcttcacccggatctggctcgcg
ctcttcggctggtggaagtgggacgacctgcccgagctcccgcccgagctgatgttcttc
cccaagtgggtcccgctcaacatctacgacttcgggtgctgggcccgccagaccatcgtg
ccgctcaccatcgtgtccgcgaagcggccggtacgccccgccccgttcaccctggacgag
ctgcacaccgacccggcgtgccccaatccgtccaggccgaccgctcccgccgccagctgg
gacggggtgttccagcggctcgacaaggcgctgcacctctaccacaaggtcgccccgcgc
cggctgcggcgcatcgccatgaacgaggccgcccgctggatcatcgaacgccaggagaac
gacggctgctggggcggcatccagcctcccgccgtgtactccgtcatcgccctgcacctg
ctcggctacgacctcgaccacccggtcatgcgggccgggctggagtcgctggaccggttc
gccgtatggcgggaggacggcgcccgcatgatcgaggcctgccagtccccggtctgggac
acctgcctcgccaccatcgccctcgccgacgcgggggtgagtcccgaccaccctgcgctc
gtgagggcggcggactggatgctcggcgaggagatcgtgcggcccggcgactgggcggtc
cgcaagcccggacttgccccgggcggttgggcgttcgagttccacaacgtcaactacccc
gacatcgacgacaccgccgaggtcgctctggcgctccgccgtgtccgccacccggacccg
gccagggtcgacgccgccatcgaacgcggggtgcgctggaacctcggcatgcagtcgcgc
aacggcgcctggggtgccttcgacgcggacaacaccagccctttccccaaccggctgccg
ttctgcgacttcggcgaggtcatcgacccgccgtcggccgacgtcaccggacacgtcgtg
gagatgctggccgtcgagggacgggcgcacgacccccgcacccggcggggcgtcgagtgg
ctgctcgccgaacaggaggcgagcggggcgtggttcggccggtggggcgtcaactacatc
tacggaacgggctccgtggtgcccgcgctgatcgcggccggcctgcccgccgcgcacccc
tcggtgcgcagggccgtcgactggctgagatccgtgcagaacgacgacggcgggtggggc
gaggacctgcgctcctaccgtgaggagaagtggatcggccacggcagctcgaccgcctca
cagaccggctgggcgcttctcgccctgctggccgcgggggagcgggagaccaggtccgtc
gagcggggagtcgcctggctggccgcgacgcagcaggccgacggctcctgggacgaaccc
cacttcaccgggaccgggttcccctgggacttctccatcaactaccacctctaccgccag
gtgttccccctgacggccctcggccggtacgtctacggcgaccccttcgcgaccgccacc
gccatcggcgccggcaccggcaagggggcctga
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