Streptomyces sp. SAT1: A8713_21345
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Entry
A8713_21345 CDS
T04706
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
strt
Streptomyces sp. SAT1
Pathway
strt00020
Citrate cycle (TCA cycle)
strt00630
Glyoxylate and dicarboxylate metabolism
strt00785
Lipoic acid metabolism
strt01100
Metabolic pathways
strt01110
Biosynthesis of secondary metabolites
strt01120
Microbial metabolism in diverse environments
strt01200
Carbon metabolism
strt01210
2-Oxocarboxylic acid metabolism
Module
strt_M00009
Citrate cycle (TCA cycle, Krebs cycle)
strt_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
strt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
A8713_21345 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
A8713_21345 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
A8713_21345 (kgd)
Enzymes [BR:
strt01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
A8713_21345 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
A8713_21345 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
A8713_21345 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
A8713_21345 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ANH93390
UniProt:
A0A1A9J0P4
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Position
complement(4913129..4916959)
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AA seq
1276 aa
AA seq
DB search
MSPQSPSNSSISTETDQAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAAASTAPAGTAAAGAAGTTTAPQAAPAAPAKPAAQAPAAPAAAQPAAPAPAQPAPAP
APAKPAAQAPAPAKAAPAAAKPAPAKAEPAAEAPAGPEFVTLRGPSAAVAKNMNASLELP
TATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNNSFAEKD
GKPTLVKPDHINLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKL
TMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGIS
KVMTLTSTYDHRVIQGAASGEFLRVVANLLLGENGFYDEIFEALRIPYEPVRWLKDIDAS
HDDDVTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVG
GFAGKSMMKLRDILGVLRDSYCRTVGIEFMHIQDPKQRKWIQDRVERPHSKPEREEQLRI
LRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGR
LNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAGGTFTGLDGEQIKVSLAANP
SHLETVDPVIEGISRAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYR
TGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEF
RQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLE
EAEQALQDYQGQLEKVFTEVREATSQPAVPQSPDPQAGFPVRVSTAISAEVVKRIAESQV
NIPDHFTVHPRLLPQLQRRAAMVEDGTIDWGMGETLAIGSLLLEGVPVRLSGQDSRRGTF
GQRHAVLIDRETGEDYTPLLYLADEQARYNVYDSLLSEYAVMGFEYGYSLTRPDALVMWE
AQFGDFANGAQSVIDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERYLQLCAQ
NNMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTTGEFRPVI
GDDSVDPSAVKKVVFCAGKVYYDLDAERKKRGATDTAIIRIERLYPLPGAELQAEIKKYP
NAEKYLWTQEEPANQGAWPFIALNLIDHLDLAVGADVPHSERLRRISRPHSSSPAVGSAK
RHQAEQEQLVREVFEA
NT seq
3831 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctccaccgagaccgaccaagccgggaag
aaccccgcggccgcgttcggtgccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaactcggtagaccgtgcctggtgggacttcttcgccgattacaagccg
ggagccgccgccgctgcctccacggctccggcgggtaccgcggccgcgggggccgcgggc
accaccacggctccccaggcggcgcccgccgccccggcgaagcccgccgcgcaggccccg
gccgcacccgccgccgcgcagcccgccgctccggctccggcgcagcccgccccggccccc
gccccggcgaagcccgccgcgcaggccccggcccccgcgaaggccgccccggccgccgcg
aagccggcgcccgccaaggcggagcccgccgccgaggcaccggccggtcccgagttcgtg
acgctgcgcggcccgtccgccgcggtcgccaagaacatgaacgcctccctggagctgccc
acggccacgtccgtgcgcgccgtcccggtgaagctgctgttcgacaaccgcatcgtcatc
aacaaccacctcaagcgggcccgcggcgggaagatctccttcacgcacctcatcggctac
gcgatggtccaggccatcaaggccatgccctcgatgaacaactcgttcgccgagaaggac
ggcaagccgaccctggtcaagccggaccacatcaacctcggtctcgccatcgacctggtc
aagcccaacggcgaccgccagctcgtcgtcgcggcgatcaagaaggccgagacgctgaac
ttcttcgagttctggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaagctg
acgatggacgacttcaccggcgtcaccgtctccctcaccaaccccggcggcctcggcacg
gtccactccgtgccgcgtctgatgcccggccagtcggtgatcatgggcgtcggctccatg
gactacccggcggagttccagggcaccagccaggacaccctgaacaagctcggcatctcc
aaggtcatgacgctcacgtcgacctacgaccaccgggtgatccagggcgccgcctccggc
gagttcctgcgtgtcgtcgccaacctgctgctcggcgagaacggcttctacgacgagatc
ttcgaggcgctgcgcatcccctacgagccggtccgctggctcaaggacatcgacgccagc
cacgacgacgacgtcaccaaggccgcccgcgtcttcgagctgatccactcctaccgggtc
cgcggccacgtcatggccgacaccgacccgctggagtaccagcagcgcaagcaccccgac
ctggacatcaccgagcacgggctcaccctgtgggacctggagcgcgagttcgccgtcggc
ggcttcgccggcaagtcgatgatgaagctgcgcgacatcctcggcgtgctgcgcgactcg
tactgccgcacggtcggcatcgagttcatgcacatccaggaccccaagcagcgcaagtgg
atccaggaccgcgtggagcgcccgcactccaagccggagcgcgaggagcagctgcgcatc
ctgcgccggctgaacgccgctgaggccttcgagaccttcctgcagacgaagtacgtcggc
cagaagcgcttctccctggagggcggcgagtccgtcatcccgctgctcgacgcggtcctc
gactcggccgccgagtcgcgcctggacgaggtcgtcatcggcatggcccaccgcggccgg
ctgaacgtgctcgccaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgag
ggcaacctcgacccgaagtcgatgcacggctccggcgacgtgaagtaccacctgggcgcc
gggggcaccttcacgggcctggacggcgagcagatcaaggtctcgctggccgcgaacccc
tcccacctggagacggtcgacccggtcatcgagggcatctcccgcgccaagcaggacatc
atcaacaagggcggcacggacttcaccgtcctgccggtggcgatccacggcgacgcggcc
ttcgcgggccagggcgtggtggccgagaccctgaacatgtcgcagctgcgcggctaccgc
accggcggcacggtccacatcgtcatcaacaaccaggtcggcttcaccgcggcgcccgag
tcctcgcgctcctcgatgtacgccaccgacgtggcccgcatgatcgaggccccgatcttc
cacgtcaacggcgacgaccccgaggccgtcgtgcgcgtggcgcggctcgccttcgagttc
cgccaggcgttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcac
aacgagtcggacaacccggccttcacccagccgctgatgtacgacctgatcgacaagaag
cgctccgtgcgcaagctctacaccgagtccctgatcggtcgcggcgacatcaccctggaa
gaggccgaacaggcgctccaggactaccaggggcagctggagaaggtcttcaccgaggtc
cgcgaggccacctcgcagccggccgtcccgcagtccccggacccgcaggccggcttcccg
gtgcgggtgagcaccgcgatctccgccgaggtcgtcaagcggatcgccgagtcccaggtc
aacatccccgaccacttcaccgtccacccgcgcctgctgccgcagctccagcgcagggcg
gcgatggtcgaggacggcaccatcgactggggcatgggcgagaccctggccatcggctcg
ctgctgctggagggcgtcccggtccggctgtccggccaggactcccgccgcggcaccttc
ggccagcgccacgcggtgctgatcgaccgcgagaccggcgaggactacaccccgctgctg
tacctggccgacgagcaggcccgctacaacgtctacgactcgctgctctccgagtacgcg
gtcatgggcttcgagtacggctactcgctgacccgcccggacgcgctggtgatgtgggag
gcccagttcggcgacttcgccaacggcgcccagtcggtcatcgacgagtacatctcggcc
gccgagcagaagtggggccagacctccggcgtcacgctgctgctgccgcacggctacgag
ggccagggcccggaccactcctcggcccgcatcgagcgctacctccagctgtgcgcgcag
aacaacatgacggtcgcgatgccgaccctgccgtcgaactacttccacctcctgcggtgg
caggtgcacaacccgcaccacaagccgctggtggtcttcaccccgaagtcgatgctgcgc
ctgaaggccgccgcctcgaagacggaggagttcacgacgggtgagttccgcccggtcatc
ggcgacgactcggtcgacccgagcgccgtgaagaaggtcgtcttctgcgcgggcaaggtc
tactacgacctcgacgccgagcggaagaagcgcggcgcgacggacaccgcgatcatccgc
atcgagcgcctgtacccgctgccgggtgccgagctccaggcggagatcaagaagtacccg
aacgccgagaagtacctgtggacgcaggaggagccggcgaaccagggtgcctggccgttc
atcgcgctcaacctgatcgaccacctggacctggcggtcggcgcggacgtgccgcacagc
gagcggctgcgccgcatctcgcgtccgcactcctcctccccggccgtgggctccgccaag
cggcaccaggccgagcaggagcagctggtgcgcgaggtgttcgaggcgtga
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