Salmo trutta (river trout): 115204363 Help Entry 115204363         CDS       T08542                                  Name (RefSeq) ryanodine receptor 1-like   KO K04961   ryanodine receptor 1 Organism stru  Salmo trutta (river trout) Pathway stru04020   Calcium signaling pathway stru04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:stru00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     115204363    04020 Calcium signaling pathway     115204363  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:stru01009]     115204363   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:stru04147]     115204363    04040 Ion channels [BR:stru04040]     115204363 Protein phosphatases and associated proteins [BR:stru01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      115204363 Exosome [BR:stru04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    115204363 Ion channels [BR:stru04040]  Voltage-gated cation channels   Ryanodine receptor    115204363 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_8 Motif Other DBs NCBI-GeneID:  115204363 NCBI-ProteinID:  XP_029625730 Ensembl:  ENSSTUG00000035043 LinkDB All DBs Position 12:80812678..80925099 Genome browser AA seq 5093 aa AA seqDB search MAEGDGEEEIQFLRTDDQVVLQCTASILKEQIKLCLSCEGFGNRLCFLETTSNAQNVPPD LAICCFILEQSLSVRALQEMLANTTELNEAVDLDKWSSQGGGHRTLLYGHAILLKHTHSS MYLSCLTTSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVS SERYLHLSYASGDLMVDASFMQTLWTMNPVMSGCELAEGFLTGGYVLRLFHGHMDECLAI PAAEQGDNQRRIAHYEGGAVCSHARSLWRLEPLRIGWSGGHMKWGQSFRVRHITTGRYLC LDEEKGLMVVDSEKANAKMSAFCFRISKEKVEVVKKRDVEGMGTPEIKYGESMCFVQHIS TGLWLTYASVDAKSARLGPLKRKAILHKEGHMDDALTMARSQTEEFQAARMIYNTAGLFT QFIKALDSLSGKNKSSSGPPSLPMDSVALSLQDLIFYFQPPEEELEHEEKQTKLRSLKNR QNLFQEEGMITLVLDCIDRLNVYNTAAHFSEFAGEEAAESWKEIVNLLYELLASLIRGNR ANCALFCDNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHG RNHKVLDVLCSLCVCNGVAVRSNQNLITENLLPGRDLLLQSNIINYVTSVRPNIFLGTCG GSTQYKKWYFEVMVDHVEPFLTAQAFHLRVGWALTDGYSPYPGGGEGWGGNGVGDDLYSY AFDGLHLWSGRVPRHVATPNMHILAADDVVSCCLDLSVPSISFRINGHPVQGMFENFNLD GLFFPVVSFSAGVKVRFLLGGRQGDFKFLPPPGYAPCYEAVLPKDRLHIEPIKEYKHDVN GVRNLLGPTQSLSHTAFTPCPVDTAQIVLPPHLERIREKLAENSHELWAVTRIEQGWTYG SFQDDNKKLHPCLVDFQSLPEPEKNYNLAMSVETLKTLLALGCHVGMGDEKAEENLKNIK MPKTYMMSSGYKPAPLDLNHVKLTPNQTNLVERLAENGHNVWARDRVHQGWTYSIVQDIM NKRNPRLVPYNLLDEKTKKTNRDTVCAAVRTLIGYGYNIEPPDQESSGHGEGHSRGDKFR VFRAEKSYAVTQGKWYFEFDAVTVGEMRVGWARPSVRADKELGADELAYVFNGFKAQRWH VGNEPFGRIWLPGDVVGCMIDLVEQNIFFTLNGEMLISDSGSEMAFKDIDIGDGFIPVCS LGLSQVGRLNLGQNVSSLRYFTICGLQEGFEPFAINMKRDITMWFSKSLPQFIPVPTEHP HVDVSRVDGTVDNAPCLKLTHKTFGSQNANTDLLFLRLSMPVEFHETFKIMAGTTPLTRT LTIPEDQVLEVDPDSDFEVLKKSASRTEKEEEKEPSVPKEISVNGGENVKDASTEKSKKK GFLFKAKKAAFTPPPVVPTMPRLMEEVVPDDRDDDDIILNTTTYYYSVRVIAGQEPSGVW VGWITPDYHQYDLHFDLSKVRNVTVTVGDDKGNIHDSMKRSNCYMVWGGEFSSSQQTRVS QEDFVIGCLIDLDTGLMTFTANGKEINTFYQVEPNTKLFPAVFVLPSSQNMLQVDLGKLK NIMPISAAMFRSERKNPVPQCPPRLDVQMLTPVIWSRMPNHFLSPETGRVNDRHGWMVEC REPLTMMALHIPEENRCIDVLELSERLDLLKFHYHTLKLYGSVCALGNNRVAHALCSHVD ESQLFYAIENTYLPGPMRSGYYDLLISMHLESAKRNRLMTNKEFIVPMTEETRSINLNSD TDKSHALPGVGLTTCLRPKLHFSPTGFVGTDLDIYTLSPFIPLHVLKAKALTMLTEAVQD GGQAMRDPVGGSVEFHFVPILKLISTLLIMGVFENEDVKHILKMIEPTVFSGEAEDAAQG EGDQTLALKERGLEVKEEEKGAVERGHETEMEDEGMGEEDEEMEAELEELEPIEKEEDEG EDDREKVDGEKGAEETEKEVKPGEAGEQVGLEEGLLHMKLPESVKLQMCTLLQYFCDCEL RHRVEAIIAFSDEFVSQVQANQRARYNELMLAYTMSAAETARKTREFRSPPQEQVNMLMN LKNIAEDEDCPVPDEVRDGLQAFHKNLLFHCSVHIEEEEVEEELDMSLKGRLLRMLDKWR HLRKKKVEEEEPEEETKPSTLQELISHTMVHWAQESFIQNPELVRLMFSLLHRQYDGLGE LIRALPKAYTINAISIKDTMDLLECLGQIRTLLIVQMGPEEERLMIQSIGNIMSNKVFYQ HPNLMRALGMHETVMEVMVNVLGGGDSKEIRFPLMVTNCCRFLCYFCRISRQNQRSMFDH LSYLLQNSGIGLGMRGSTPLDVAAASCIDNNELALALQEQDLEKVVKYLAGCGLQSCPQL LAKGYPDIGWNPCGGEKYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALRGEGG NGLLAAIEEAIKISEDPARDGPTVKKDRRFPGMFPGGEGQHEENKVHLGNAIMSFYSALI DLLGRCAPEMHLIQAGKGEALRIRAILRSLVPIEDLVGVISLSVQIPDFGKDNSIIEPKM SSSFVPDHKAPMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRAAASLDTVAFCTTEMALAL NRYLSLAVLPLITKCAFLFAGTDHRAIMIDSMLHTIYRLSRGRAFTKAQRDVIEECLMAL CKNLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWGNFGVSSEE ELHLTRKLFWGIFESLAHKKFDAELFKIAMPCICAIAGAIPPDYVDASYSSKTEKKASVD AEGNFDPKPVETTNTIIPERLDGFINKYAEYTHDKWAFEKIQNNWTYGEMLDEDSKTHPM LRPYKTFSEKDKEIYRWPIKESMKAIIAWEWTLDQTREGEEAKTEQKKAARKISQTAQAT YDPSQGYSPQPIEISHMALSRELQSMAEQLAENYHNTWGRKKKMELQSKGGGSHPLLVPY DTLTAKEKARDREKAHELLKFLQLNGFAVTRGMKDMESDISSIEKRFAYGFLQKLLKWME IAQEFIAHLEAVVSSGRVEKSPHEKEIKFFAKILLPLINQYFKNHCLYFLSTPAKVLGSG GHSSNKEKEMIASIFCKMAALVRHRVSLFGNDAPAIVNCLHILARSLDARTVMKSGPEIV KAGLRSFFEGAADDIEKMVENLKLGKVSKGNQQVKGVSQNINYTTIALLPVLTSLFDHIS QHQFGDDVILDDLQMSCYRIMCAIYSLGTVKNPHVERQRPALGECLAHLAAAMPVAYLEP HLNEYNSFSVYTTKTPRERGILGLPNEVQELCQDIPELDVLLKEIGDLAESGARYTEMPH VIEITLPMLCNYLPRWWERGVENFPELEGQICTDVTSEQLNQLLGSIMKIVVNNLGIDEA SWMKRLAVFSQPIVSRAKPEMLKSHFIPTMEKLKKRTGKVVAEEDHLRMEGKAEGDEEEG TIREEFAVLCRDLYALYPLLIRYVDNNRARWLTCPDPDAEELFRMVGEVFIFWSKSHNFK REEQNFVVMNEINNMSFLTADSKSKMSTGNDSEAGGSDVERTKKKRRGDRYSVQTSLIVA ALKKMLPIGLNMCSPADQELINLAKIRYSLRDTDEEVREFLQNNLHLQGKVENPSMRWQM SLYKEMAGKAEDADAPEKVVKRVQEVSAVLYYIEVTEHPFKSKKMVWHKLLSKQRRKAVV ACFRMTPLYNLPRHRASNMFLEGYKRNWIHTEGYSFEDRMIDDLSKAMDQEGEEEEETET KPDPLHQLILHFSRTALTEKSKLDTDYLYMAYADIMAKSCHIGEEDEGGEEVEEGAEDEM SFEMRQTELEKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGCMVSSTLKLGISIL NGGNVEVQQKMLEYLKDKKDVGFFLSVQALMQTCSVLDLNAFERQNKAEGLGMLSEEGTS EKVMSDDEFTCDLFRMLQLLCEGHNDDFQNYLRTQTGSTTTINIIICTVDYLLRLQESIS DFYWYYSGKEIIDEPGKKNFSKAMTVAKQIFNSLTEYIQGPCTGNQQSLTHSRLWDAVVG FLHVFAHLMMKLAQGKDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLV ESSSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFQKAMDSQKQYSPSEIQ FLLSCSEADENDMINFEEFADRFQEPAKDIGFNIAVLLTNLSEHVPHDLRLKNFLEQAES VLNYFRPFLGRIEIMGASRKIERIYFEISEVNRTQWEMPQVRESKRQFIFDVVNEGGESE KMEMFVNFCEDTIFEMNIASQISEQEEEEKEEDDDDPAEGGTDAGGGGGDEEGNGEEGEP ESISAFADFINSLLNFLSIFTFRNLRRQYRRVRKMTIKQIVVGLATFFWTILIGILHFIY SVCKGFFLLIWQTLFGGGLVEGAKNITVTEILASMPDPTQDEVHGDLPGEPEVGKEQEAG GVTDPIDTGGGEEEEEEDKKDKEGGGTPRIDAPGGLGDMGIEATVEPPTPEGTPLTKRKR QPEEGAAAAPDGQAVDGQAADGLAAEPAPAIKEPPPEPEKADTENGEKAEKEAENKEEKQ EEAIEKKPKSKKDKKQHREQGFQLWTELDIQRNKFLNYLSRNFYNLRFLALFIAFALNFI LLFYKVSDSPPGEGDEVEGSGMFEGSGLGVLFEGSGLFEGSAEEMEGSGGEEGGDEEEEG GPVYFFLEESTGYMQPTLTFLATLHTVIAFLCIIGYNCLKIPLVIFKREKELARKLEFDG LYITEQPEDDDIKGQWDRLVLNTLSFPSNYWDKFVKRKVLDKYGDIYGRERIAELLGMDL ASLDVSQQTDKKLEEPDNSTLAWFTSIDFKYQIWKFGVVFTDGTFLYLCWYTIMSFLGHY NNFFYACHLLDIAIGVKDLRTILSSVTHNGKQLMMTLGLLAVVVYLYTVVAFIFFRKFYN KSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDVYELYRVVFDITFFFFV IVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHN LANYMFFLMYLINKDETEHTGQESYVWKMYQERAWDFFPAGDCFRKQYEDQLA NT seq 15282 nt NT seq  +upstreamnt  +downstreamnt atggcagaaggagatggagaggaggagattcagttcctgcgtacggatgaccaggttgtg ctacaatgcacagcctccattctgaaagagcagatcaaactgtgtctgtcatgcgaaggc tttgggaaccgcctctgcttcctggagaccacctctaatgctcagaatgtgccacctgat ttggcgatctgctgcttcatcctggagcagtccttgtcggtacgagccttacaggagatg ctggccaacaccacggaactcaatgaggcagtcgatttggacaaatggtcatctcaagga gggggccaccgtaccctgctgtatggccacgctatccttctgaaacacactcactccagc atgtacctcagctgtttgactacctcaaggtcactcacagacaaactggcctttgatgtg gggttacaggaagattccacaggggaggcatgctggtggaccattcatcctgcgtccaag cagagatcagagggagagaaggtcagggtgggagatgacctcatcctggtcagtgtgtcc tctgagagatacctgcatctctcctatgccagtggtgacctcatggtggacgcctccttc atgcagaccctgtggaccatgaaccctgtgatgtctggctgtgaacttgcggaaggcttt ctgactggaggctatgttcttagactgttccatggtcacatggacgagtgcttggctatc cctgctgccgagcaaggagacaaccagcgcagaattgctcattatgaagggggtgctgtc tgtagccatgcccggtcactatggagactagaacccctccggattggatggagtggaggt cacatgaaatggggccagtcgttccgagtgcgtcatataaccacaggtcgctacctctgc ctggatgaagagaaaggactgatggtggtggactctgaaaaagccaacgccaagatgtca gccttctgcttcagaatctccaaggaaaaggtggaggtggttaagaagcgagatgtggag ggcatgggcacgccagagatcaagtatggggagtccatgtgttttgtacagcacatctcc actggcctctggcttacatacgcctctgtcgatgccaagtccgctcgcctgggacctctt aagaggaaggccatccttcataaggagggccacatggacgatgccctgaccatggcccgc tcccagacagaggagttccaggctgctcgtatgatctacaacacagcaggcctcttcacc cagttcatcaaagcgctggactctctgagtgggaagaacaagtcatcttcaggccccccg tctctgcccatggactcagtggccctctccctgcaggacctcatcttctacttccagccc ccagaggaggagctggagcacgaggagaaacagaccaaactacgctcccttaagaacaga cagaacctcttccaagaggagggcatgatcaccctggtgctggactgtattgaccgactc aatgtctacaacacggcggcccacttctccgagtttgcaggggaggaggctgccgagtct tggaaggagatagttaatctcctctatgagctgctggcctcactgatcagggggaaccgg gcaaactgtgcactgttctgtgataatctggattggctggtcagcaaactggaccgtctg gaggcctcctcaggcatcctggaggtgctatactgtgttctgattgagagtccagaggtt ttgaacattatccaggagaaccacattaaatctatcatttctctactggataagcatgga cgcaatcacaaggtgttggatgtgctctgctctttgtgtgtgtgtaatggggtggctgta aggtccaatcagaatctcatcacagagaatctgcttccgggtcgcgatctcctcctgcag tccaacatcatcaattatgtcaccagtgtgaggcccaacatcttcctaggaacgtgtgga ggatcaactcagtataagaagtggtattttgaggtgatggtggaccatgtagagcccttc ctgaccgcccaggccttccacctgcgtgtgggctgggctctgactgatggctacagcccc taccctggaggtggtgagggctggggtggtaacggggtgggggacgacctctactcatac gcctttgatggactccacctgtggtcaggacgagtcccacgtcatgtcgccacccccaac atgcacatcctagccgcagacgatgtggtcagctgctgccttgatctgagtgtgcccagt atttcgttccgtatcaacgggcacccggtgcagggcatgtttgagaacttcaatctggat ggcctattcttccctgtcgtcagcttctctgcaggcgtcaaggttcgttttctcctggga gggcgtcagggagactttaaattcctcccacccccaggctatgctccatgctatgaggct gtgctacccaaggatcgactgcatattgagcccatcaaggagtataagcatgatgtcaat ggtgtccgcaatctgttggggcctacacagtccctctcgcacacagccttcaccccttgc cctgtggacacagcacagattgtgcttccacctcacttggagcgcattcgggagaagctg gcagaaaacagccatgagctatgggctgtcactcgcattgaacaaggatggacctatggg tcgttccaagatgacaacaagaaactgcacccctgcctggtagatttccagagcctgcca gagccagagaagaattacaaccttgccatgtcagtagaaacactcaagactctactggcg ctgggctgccatgtgggcatgggagatgagaaagcagaggagaacctgaagaacatcaag atgcccaagacgtatatgatgagtagtggatacaagcctgcccctctggacctcaaccat gtcaagctgacacccaaccagactaacctagtggagagactggcagagaatgggcacaat gtgtgggctcgtgacagggttcaccagggatggacctacagcattgtacaggacataatg aacaagcgcaacccgcgcctggtgccatacaacctgctggacgaaaagaccaagaagacc aacagagacactgtctgtgcagctgtccgcactctcatcggctacggttacaacattgag ccacctgaccaagagagcagtggtcatggggaaggtcattcccgtggagataagttccgg gtgttccgagctgagaagtcatacgcggtgacccaggggaagtggtactttgagtttgat gctgtgactgtgggggagatgagagtgggttgggccagacccagtgtccgcgctgacaaa gagctgggagcagacgagctcgcctatgtcttcaatggtttcaaggctcaacgttggcat gtgggcaatgagccgtttggtcgtatctggttgccaggtgacgtggtgggctgtatgatt gacctggtagagcagaacatcttcttcaccctgaacggagagatgctcatcagtgactct ggctctgagatggccttcaaggacattgacataggagatggttttatccctgtgtgtagt ctgggcctgtctcaggttggccggctcaacctgggccagaacgtcagcagcctgcgctac ttcaccatctgtggccttcaggagggctttgaacccttcgccatcaacatgaagagagac attaccatgtggttcagcaagagcctgccccagttcattcctgttcctacagagcaccct cacgttgatgtgtcccgtgtggatgggacggtggacaatgctccctgtcttaaactgacc cacaagaccttcggttctcagaatgccaacaccgatctgctgttcctgaggctcagtatg cccgtggagttccacgagacctttaaaatcatggctgggaccacccccctgacacgaacc ctgaccatccccgaggaccaggtcctggaggtggaccccgactctgactttgaggtgctg aagaagtctgccagccgcacagagaaggaggaggagaaggagccctctgtgcctaaggag atctccgtcaacggaggagagaacgtgaaagatgcctctacagagaagagcaagaagaag gggttcctgttcaaggccaagaaggcagctttcactccgccccctgttgttcccaccatg ccccgcctgatggaggaagtggtcccagacgacagagatgacgatgacatcatcctcaac accaccacatactattattcagtgcgagttattgcgggacaagagcccagtggggtgtgg gtaggctggatcacccctgactaccatcagtacgacctgcactttgacctcagcaaagta agaaatgtcacagtcaccgtgggagatgacaaaggcaacatacatgacagtatgaagcgc agtaactgctacatggtgtggggaggggagttcagcagctcccagcagacccgtgtcagt caggaggactttgtgattggctgccttattgacctggacacaggactcatgactttcaca gccaatgggaaagagatcaacaccttctaccaggtggagcccaacactaaactgttccca gctgtctttgtcctgccctccagtcagaacatgctgcaagtggacctggggaagctcaag aacataatgcctatttcagcagccatgttccgcagtgagcgtaagaacccggtccctcag tgtcctcccaggctggatgtccagatgctgaccccagtcatttggagccgcatgccaaac cacttcctgtccccagagacgggccgtgtgaacgacaggcacggttggatggtggagtgt agagagcctctcaccatgatggccctgcacatccctgaggagaacagatgtattgacgtc ctggagttgtcggagcgtttggacctgctgaagttccactaccacactctgaaactgtac ggctcggtctgtgccctggggaacaaccgcgtggctcacgccctgtgcagccatgttgac gagtctcagctattctacgccatagagaacacctacctgcctggaccaatgaggagcggc tactacgatctgctcatcagcatgcacctggagtcggccaagaggaaccgcctcatgacc aataaggagttcattgtgcccatgactgaagagacgcgcagcatcaacctcaactcagac actgacaaatcccatgctttaccaggggtgggcctcactacctgtctgcgccccaaactc cacttctcccccactgggtttgtagggacagacctggatatctacaccctcagccccttc atccccctacatgtgctgaaggcgaaggccctgaccatgctgacagaggctgtccaggat ggtggtcaagccatgagggatcctgtaggaggcagtgttgagttccactttgtccccatc ctcaagcttatcagcaccctgctcatcatgggtgtgtttgagaatgaagatgtcaagcac atcctgaagatgattgagcccacagtgttcagtggagaggcagaggatgctgcccaggga gagggggaccaaacattggccctcaaagaacggggattggaggtgaaggaagaagagaag ggagcagtagagaggggacatgaaacagaaatggaggatgaggggatgggtgaggaagat gaggaaatggaggcagagctggaggagttggagcctatagaaaaagaggaagacgagggg gaggacgacagagagaaagtggatggagagaaaggtgctgaggagacggagaaggaggtg aagcctggagaggcaggagaacaagtaggtctggaagaggggttactgcacatgaagctg ccagagtctgtcaagctacagatgtgcactctgctgcagtatttctgtgactgtgagttg cgccacagggtggaggccatcatagccttctcagacgagtttgtgagccaggtgcaggcc aaccagagagcccgctacaacgagctcatgctggcgtacaccatgagcgctgctgagacc gctcgcaagacccgcgagttccgctccccaccacaggagcaggtcaacatgctgatgaac ttgaagaacattgcggaggatgaggattgtcctgtgcctgacgaggtccgcgatggtctg caggcttttcacaagaacctgctgtttcactgcagtgtacatatcgaagaggaagaggta gaggaggagttggatatgtctctcaaaggacgactcctccgaatgctggacaagtggagg cacctccgtaagaagaaggtagaggaggaggaacctgaggaggagaccaaacccagcacc ctccaggagctgatctcccacaccatggtccactgggcccaggagtcattcatccagaac cctgagctggtgcgtctgatgttcagcctgctgcaccgtcagtatgacgggctgggggag ctgatccgggccctgcccaaagcctacaccatcaacgccatctccataaaggataccatg gacctgctggagtgcctgggacagatccgcacgctgctcatcgtccagatgggccccgag gaggagaggctcatgatccagagcatcgggaacatcatgagcaacaaagtgttttatcag caccccaacctgatgcgagcgctgggcatgcacgagactgtcatggaggtgatggtcaac gtgctgggtggtggcgactccaaggagatcagattccctcttatggtcaccaactgctgt cgtttcctgtgctacttctgtcgtatcagtcgtcagaaccaacgctccatgttcgatcac ctcagctacctgcttcagaacagtggcatcggccttggaatgcgtggctccacccctcta gacgtagctgcagcatcctgtattgataacaatgagctggctctggctctacaggaacaa gacctggagaaggtggtgaagtaccttgcaggctgtgggcttcagagctgtccccagctc ctggctaagggttaccctgacattggctggaacccttgtggcggagagaaatacttggac ttcctccgcttcgctgtctttgtcaacggagagagcgtagaagagaatgccaatgtggtg gtgcgtcttctgatccgtcggccagagtgttttggcccggctctgagaggagagggtggg aacggcctgctggctgctatagaggaggccatcaagatctctgaggatcctgccagggac ggccccactgtcaagaaagacaggcgcttccccggcatgttccctggtggagaagggcag catgaggagaacaaggtgcatcttgggaatgccatcatgtccttctactcagctctcatt gacttgctgggacgctgcgctccagagatgcatttaatccaggctgggaagggtgaggct ctgaggatcagggccatcctgaggtccctggtgcccatagaggacctagtgggagtcatc agcctgtctgtccaaatcccagactttggaaaggataacagcatcattgaacccaagatg tcttccagttttgtgccggaccacaaggctcccatggtgctgttccttgacagagtgtat ggtattgacaaccaggacttcctgctccatgtgctggaggtgggcttcctgcctgacatg agggcagctgcttctctggacacagtggctttctgcaccacagagatggccctggctctg aaccgctacctctctctggccgtgctgcccctcatcaccaagtgtgccttcctgtttgcc ggcaccgaccaccgggccatcatgatcgactccatgctgcacaccatctaccgtctgtcc cgcggacgagccttcacaaaggcccagagagatgttattgaggagtgtctcatggctttg tgcaaaaatctacggccatccatgttacaacacctgttgagaaggctggtgtttgatgta ccaattctcaatgaatatgccaaaatgccacttaagcttttgaccaatcactatgagcgt tgttggaagtactattgcctgcccaacggctggggcaactttggagtgtcatcagaggag gagctgcatctcacccgcaaactcttctggggcatctttgagtccctggcccacaagaaa tttgatgctgagctgttcaaaattgccatgccgtgcatatgtgccattgctggcgccatc cctccagattatgtagatgccagctactcctccaagactgagaagaaagcctcggtggat gcagagggaaactttgatcccaaaccagtggagaccacaaatactatcatccctgagaga ttggatggtttcatcaacaaatatgctgaatacacacatgacaagtgggcttttgaaaag attcagaataactggacgtatggagagatgttggatgaagattctaaaactcaccccatg ctccgaccgtacaaaacattctcagagaaggacaaagagatctaccgttggcccatcaaa gagtccatgaaggctataattgcgtgggagtggactctggatcaaacgagggaaggagag gaagccaagactgagcaaaagaaggcggctcggaaaatctctcagactgcacaggcaacg tacgaccccagccaaggctacagtccccaaccgattgaaatctcccacatggcactgtca agagagctgcagtccatggcagaacagcttgcagagaactatcacaatacctggggtcgc aagaagaagatggagctgcagtccaaaggaggaggctcccaccctttgcttgtaccctac gacaccctgacagcaaaggaaaaggcacgagacagggaaaaggctcatgagcttcttaaa ttccttcaactcaatggatttgcagtcaccagggggatgaaagacatggagtcagacatc tcgtctatcgagaagcgttttgcttatggtttcctgcagaagttgttaaagtggatggag atcgcccaggagttcatagctcatcttgaggctgtggtgagcagtggcagagtggagaag tcgcctcatgagaaggagatcaaattctttgcaaagatcctgttgcccctgatcaatcag tactttaaaaaccactgtctgtacttcctgtccacaccggccaaagtcctgggtagtgga ggacattcctctaacaaggagaaggagatgattgccagcatcttctgtaaaatggctgct ctggtgagacacagagtttctctctttggaaatgacgcccctgctattgtcaactgtctt cacatcctggcacgatctctcgacgcaaggacggtgatgaagtctgggcctgaaatcgtg aaggcagggctcaggtcattctttgagggtgcagctgatgatatagagaagatggtggag aacctcaaactgggaaaggtgtctaaaggcaaccagcaggtgaaaggcgtgtcccagaac atcaactacaccaccattgctctgctcccagtcctcacctccctgttcgaccacatctct cagcaccagtttggagatgatgtcattttggatgatctccagatgtcgtgttaccgcatc atgtgcgccatctactcgttgggcactgtcaagaaccctcatgtggagaggcagaggcca gccctgggggagtgtctggcccatctggcggctgctatgcctgtggcctacctggagccc catctcaatgagtacaactccttctctgtttacaccaccaagacccccagagaaagaggc atcctgggtctgcccaatgaggtccaggagttatgccaggacataccagagctagacgtt ctattgaaagagatcggggacttggcagagtcaggtgcccgttacacagagatgccccat gtaatcgagataactctgcccatgctgtgtaactacctgccccgctggtgggaaagagga gtagagaacttccctgagctggagggccagatctgcaccgacgtcacctctgagcagctc aaccagctgctgggcagcatcatgaagatcgtcgtcaacaacctgggaattgacgaggcc tcctggatgaagaggctggctgtcttctcccagcctattgtgagcagggccaagccagag atgctcaagtcccatttcatccccaccatggagaagctgaagaagaggacagggaaggtg gtggccgaggaggaccacctgcgtatggaggggaaggccgagggagacgaggaggagggc accatcagggaggagtttgctgtgctctgcagggacctgtacgccctctaccctctcctc atccgctatgtggacaataacagggcaaggtggttgacatgcccagacccagatgcagag gagctcttcagaatggttggagaggtcttcattttctggtccaaatctcataacttcaag cgagaggagcagaactttgtggtgatgaatgagattaataacatgtctttcctcactgct gacagcaagagcaagatgagcacgggcaacgactcggaggctggtggctcagatgtggag cgtaccaagaagaaaagacggggagatcgttattcagtgcagacgtcacttattgtggct gccctgaaaaagatgctccccatcggcctcaacatgtgctcccctgctgatcaggagctt attaacctggccaagatacgatactctttgagggacacggatgaggaagtaagggagttt ttgcaaaacaacctgcatcttcaaggcaaggtggagaacccgtccatgcgctggcagatg tccctgtataaggagatggcagggaaggctgaggatgctgacgctccagagaaggtggtg aagagggtgcaggaggtgtcagctgttctttattacattgaggtgactgagcaccccttc aaatccaaaaagatggtgtggcacaaactgctctccaagcagagacgcaaggctgtggta gcctgctttaggatgactccactctacaacctacccaggcatagagcttccaatatgttc ctggaaggatacaaacgcaactggatccatactgagggctactcctttgaggacagaatg atagacgacttgtctaaagccatggaccaggaaggagaggaagaggaagagacagagacc aagccagatccccttcaccaactcattttgcatttcagccgtacggctctcacagaaaag agtaaacttgatacagattacctatatatggcatacgctgatattatggcaaagagctgc cacattggtgaggaggatgaagggggagaggaggtggaggaaggggctgaggatgagatg tcctttgagatgcgacagacagaactggaaaaagagatggagaaacagagacttctgtac cagcagtcccgtctccataaccgtggggcggctgagatggtgctgcagatgatcagtgct tgcaaaggtgagactggctgtatggtgtcctccacccttaaactgggcatctccatccta aacggtggtaacgttgaggttcaacagaaaatgcttgagtacctgaaggacaagaaggat gttggcttctttttgagtgtccaggctctaatgcagacatgcagtgtcctggacctgaat gcctttgagagacagaacaaggcagagggtctgggaatgttgtcggaggagggaacaagt gaaaaagtcatgtcagatgatgagtttacatgtgatctgttccgcatgttgcagctgctc tgtgagggccacaatgacgatttccagaactacttgcggacacagacaggcagcaccacc actatcaacatcatcatctgcactgtggattacctcctccgactgcaggagtcaatcagt gatttctactggtattactctgggaaagagatcatcgatgagccaggcaagaagaacttc tccaaggccatgacagtggctaaacagatctttaacagtctgactgagtacatccagggt ccgtgtacaggcaaccagcagtccctgacccacagcaggctgtgggatgcagtagtaggc ttcctccacgtctttgcccacttaatgatgaagctggcacagggtaaagactccagccag attggcctgctgaaggagctactggacctccagaaagacatggtggttatgttgctctct ctactagagggtaatgtggtgaacggcaccattgcccgtcagatggtggacatgctggtg gaatcctccagcaacgtggagatgatcctcaagttctttgacatgttcctcaaactgaag gacattgtggcgtcagacgccttccgtgattacgtgactgacccccgagggttaatctct aagaaagactttcagaaggccatggacagccagaaacagtattctccctccgagatccaa ttcctgttgtcatgctcagaggctgatgagaacgacatgataaactttgaggagtttgcc gaccgcttccaggagccagctaaagacattggctttaacattgcagtgttgctgaccaac ctgtctgaacatgtgcctcatgacctcaggctgaagaacttcctagagcaggcagagagt gtactcaactacttccgccccttcctgggccgtatagagatcatgggtgccagcaggaag atagagcgtatttactttgagatcagcgaggtaaaccgcacacagtgggagatgcctcag gtcagagagtccaaacgacagttcatctttgatgtggttaatgaggggggcgagtcggag aagatggagatgtttgtcaacttctgcgaggacactatctttgagatgaacatcgcctcc cagatctcggaacaggaggaggaggagaaggaggaggatgatgatgatccagctgaagga ggaactgatgcaggaggaggaggtggagatgaagaaggcaatggagaggaaggagagcca gagtccatctctgcctttgcagacttcatcaacagcttattgaacttcctgagtatcttc acattccgtaacctgcgacggcagtaccgcagggtaaggaagatgaccatcaagcagata gtggtgggtctggctaccttcttctggactatcctcatcggcatcctgcacttcatctac agtgtatgtaagggcttcttcctgctcatctggcaaactctatttggcggaggcctggtg gagggagcaaagaacatcacggtgacagagatcctggccagtatgcctgaccccacccag gatgaggtgcatggggacctgccaggggagcctgaggttgggaaggagcaggaggcagga ggggtgactgacccaatagacacaggtggtggagaggaggaggaggaggaggacaaaaaa gacaaggaaggtggggggaccccacgcatcgatgctcctggtggacttggtgacatggga attgaggccactgttgagcctcctactcctgagggaactcctttgaccaagaggaaacgg caaccagaggagggtgctgctgcagcacctgatggccaagctgttgatggccaagcagct gatggcctagctgctgaaccggctcctgccataaaggagccccctccagagcctgagaag gcagacactgaaaatggagagaaggccgagaaagaagctgagaacaaagaggagaagcag gaggaagcgatagaaaagaaacccaagtctaagaaagataagaagcaacacagggagcaa gggttccaactctggactgagctggacatccaaagaaacaaattcttgaactacctctct cggaacttttacaatctgcgttttctggcactgttcattgcatttgccctgaactttatt ctactcttctacaaggtgtcggacagcccccctggagaaggtgatgaggtggagggctct ggcatgtttgagggctcagggttgggagtgctgtttgagggaagtgggctgtttgagggc tcagcggaggagatggagggatctggtggggaggaaggaggagacgaggaagaggagggg ggcccagtctacttcttcttggaggagagcactggctacatgcagcccaccctcaccttc ctggctaccctgcacaccgtcatcgccttcctctgcatcatcggttacaactgtctaaag atccctcttgtgatctttaaaagagaaaaggagttggccaggaaactggagtttgatggt ctttacatcacagagcagcctgaggatgatgacatcaaaggccaatgggacagactggtc ctcaacacactctctttcccaagcaactactgggacaagtttgttaagcgaaaggtcctg gataagtatggagacatttacggcagagagaggattgcagagctcctaggcatggattta gcctcgttggatgtcagtcaacaaactgataagaagctggaggaacccgacaattctacg ttggcctggtttacgtctattgacttcaagtaccagatctggaaatttggagttgtgttc acagacgggacttttctctatctgtgttggtacacgatcatgtcctttcttggacattac aacaacttcttctatgcctgtcacttgctggacatagccatcggtgtgaaggatctgcgt actatcctgtcctctgtcacccacaatgggaaacaactcatgatgacattgggcttgttg gcagtggtggtgtatctctacactgtagtggcctttatctttttccgcaagttttacaac aagagtgaagatgaggatgagccggatatgaaatgtgatgacatgatgacttgctacctc ttccatatgtacgtgggcgtgcgtgctggcggtggcataggggacgagatcgaggacccg gcaggagacgtgtacgagctctaccgggtcgtctttgacatcacctttttcttctttgtc attgtcatcctgttggccatcatccagggtctgatcattgatgccttcggagagctcaga gaccaacaggagcaggttaaggaagacatggagaccaagtgcttcatctgtggaattgga agcgactactttgatacgacaccgcacggcttcgagacccacaccctggaggaacacaac ttggccaactacatgttcttcttaatgtacctcatcaacaaagatgagacggagcacact ggccaggagtcgtatgtgtggaagatgtaccaggagcgagcgtgggacttcttccctgct ggcgactgtttcagaaagcaatatgaggatcagcttgcataa

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