Streptomyces sp. VN1: EZV63_10135
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Entry
EZV63_10135 CDS
T10674
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
strv Streptomyces sp. VN1
Pathway
strv00010
Glycolysis / Gluconeogenesis
strv00020
Citrate cycle (TCA cycle)
strv00620
Pyruvate metabolism
strv00785
Lipoic acid metabolism
strv01100
Metabolic pathways
strv01110
Biosynthesis of secondary metabolites
strv01120
Microbial metabolism in diverse environments
strv01200
Carbon metabolism
strv01210
2-Oxocarboxylic acid metabolism
Module
strv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
Enzymes [BR:
strv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EZV63_10135 (aceE)
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NCBI-ProteinID:
QIP70219
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Position
2247045..2249801
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AA seq
918 aa
AA seq
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MASASDRSDRSPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERA
REKRVAVPEMRSTDYVNTIPTKSEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVG
GHIATFASSASLYDVGFNHFFRGKDDGDGGDQVFFQGHASPGIYARAYLLDRLSEEHLDG
FRQEKSKAPHALSSYPHPRSMPDFWEFPTVSMGLGPIGAIFQARMNRYMHARGIADTSRS
HVWAYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESVF
RGAGWNVIKLVWDRTWDPLLAQDRDGVLVNRMNTTPDGQFQTYATESGAYIRDHFFGDDH
RLRTMVENMTDDQILHLGRGGHDHRKIYAAYKAALEHKGQPTVILAKTIKGWTLGPNFEG
RNATHQMKKLTVDDLKRFRDRLHLPISDKELESGPPPYYHPGRDTEEMQYMHDRRLGCGG
YVPTRVVRSKPLPLPDDKTYATVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAP
DEYRTFGMDSFFPSAKIYNPLGQQYESVDRELLLAYKEAPNGQMLHDGISEAGCTASLIA
AGSAYATHGEPLIPVYVFYSMFGFQRTGDQFWQMGDQLARGFVLGATAGRTTLTGEGLQH
ADGHSQLLASTNPACVAYDPAFGFEIAHIVKDGLRRMYGGDEQHPHGEDVFYYLTVYNEP
IRHPAEPENVDVEGILKGVHRFSEGTGGAIPAQIMASGVAVPWAVEAQRILAEEWNVRAD
VWSATSWNELRREAVACEEHNLLHPEEEQRVPYVTRKLAGAQGPFVAVSDWMRSVPDQIA
RWVPGTYQSLGADGFGFADTRGAARRFFHIDAESVVVGVLGELAREGKVDRSVLKQAIDR
YRLLDVTAADPGPAGGDA
NT seq
2757 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccgcatccgatcgcagcgatcgcagtccgatcatcattggcggcctcccgagt
caggttcccgacttcgatcccgaggagacccaggagtggctcgactccctcgacgccgcc
gtcgacgagcgcggccgggaacgggcccggtacctgatgctgcggctgatcgagcgggcc
cgcgagaagcgcgtggccgtgcccgagatgcgcagcacggactacgtcaacaccatcccg
accaagagcgagccgttcttcccgggcaacgaggagatcgagcgcaagatcctcaacgcc
acccgctggaacgccgcggtgatggtctcgcgcgcgcagcgccccggcatcggcgtcggc
ggccacatcgcgaccttcgcctcctcggcgtccctgtacgacgtgggcttcaaccacttc
ttccgcggcaaggacgacggcgacggcggcgaccaggtcttcttccaggggcacgcctca
ccgggcatctacgcccgcgcctacctcctcgaccggctcagcgaggagcacctcgacggc
ttccggcaggagaagtcgaaggcgccgcacgcgctgtcgtcgtacccgcacccgcggtcg
atgccggacttctgggagttcccgacggtctcgatgggcctcggcccgatcggcgcgatc
ttccaggcgcggatgaaccgctacatgcacgcgcgcggcatcgcggacacctcgcgctcg
cacgtgtgggcctacctgggcgacggtgagatggacgagccggagtcgctgggccagctg
tccatcgcggcccgggagggcctggacaacctgaccttcgtggtcaactgcaacctgcag
cgcctggacggcccggtgcgcggcaacggcaagatcatccaggagctggagtcggtcttc
cgcggcgccggctggaacgtgatcaagctggtctgggaccgcacctgggacccgctgctc
gcccaggaccgcgacggcgtgctggtcaaccgcatgaacacgaccccggacggccagttc
cagacctacgccaccgagtccggcgcgtacatccgcgaccacttcttcggcgacgaccac
cggctgcgcacgatggtcgagaacatgaccgacgaccagatcctgcacctgggccgaggc
ggccacgaccaccgcaagatctacgcggcgtacaaggcggcgctcgaacacaagggccag
ccgacggtcatcctggccaagacgatcaagggctggacgctgggccccaacttcgagggc
cgcaacgccacgcaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgac
cggctgcacctgccgatctccgacaaggagctggagtccggcccgccgccgtactaccac
ccgggccgggacaccgaggagatgcagtacatgcacgaccggcgcctgggctgcggcggg
tacgtgccgacccgggtcgtgcggtcgaagccgctcccgctgccggacgacaagacgtac
gcgaccgtgaagaaggggtcgggccagcagtccatcgcgacgacgatggccttcgtgcgg
ctactgaaggacctcatgcgggacaaggagatcggcaagcgcttcgtgctgatcgcgccg
gacgagtaccgcacgttcggcatggactcgttcttcccgagcgcgaagatctacaacccg
ctcgggcagcagtacgagtccgtggaccgcgagctgctcctcgcctacaaggaggcgccg
aacgggcagatgctgcacgacggcatctccgaggccggctgcacggcgtcgctgatcgcg
gcgggctcggcgtacgcgacgcacggcgaaccgctgatcccggtgtacgtgttctactcg
atgttcggattccagcgcaccggcgaccagttctggcagatgggcgaccagctggcgcgc
ggtttcgtgctgggggcgaccgccggccgtacgaccctgaccggcgagggcctccagcac
gccgacggccactcgcagctgctcgcctcgaccaacccggcgtgcgtggcgtacgacccc
gccttcgggttcgagatcgcgcacatcgtcaaggacgggctgcgccggatgtacggcggg
gacgagcagcacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagccc
atccggcacccggccgagcccgagaacgtggacgtcgagggcatcctcaagggcgtccac
cgcttcagcgagggcaccggcggcgcgatcccggcgcagatcatggcgtccggcgtcgcg
gtgccgtgggccgtggaggcccagcggatcctcgccgaggagtggaacgtacgggccgac
gtctggtcggccacctcctggaacgagctgcggcgcgaggccgtggcctgcgaggagcac
aacctgctgcaccccgaggaggagcagcgggtgccgtacgtgacccggaagctggcgggc
gcgcaggggccgttcgtggcggtgtccgactggatgcggtcggtgccggaccagatcgcc
cgatgggtgccggggacgtaccagtcgctgggcgcggacgggttcggcttcgcggacacg
cgcggggcggcgcggcggttcttccacatcgacgcggaatcggtcgtggtcggggtgctg
ggcgagctggcgcgggagggcaaggtcgaccggtcggtgctgaagcaggcgatcgaccgg
taccggctgctcgacgtgacggcggccgacccgggcccggcgggcggggacgcgtga
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