Streptomyces sp. WP-1: QHG49_24215
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Entry
QHG49_24215 CDS
T10379
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
strw Streptomyces sp. WP-1
Pathway
strw00010
Glycolysis / Gluconeogenesis
strw00020
Citrate cycle (TCA cycle)
strw00620
Pyruvate metabolism
strw00785
Lipoic acid metabolism
strw01100
Metabolic pathways
strw01110
Biosynthesis of secondary metabolites
strw01120
Microbial metabolism in diverse environments
strw01200
Carbon metabolism
strw01210
2-Oxocarboxylic acid metabolism
Module
strw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
Enzymes [BR:
strw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
QHG49_24215 (aceE)
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NCBI-ProteinID:
WKE71892
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Position
complement(5489047..5491794)
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AA seq
915 aa
AA seq
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MASGSDRTPIIIGGLPSQVPDFDPEETQEWLDSLDAVVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIPTKSEPFFPGNEEIERRILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAYLLDRLTENQLDGFRQ
EKSAYPNGLSSYPHPRSMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEPESLGQLTLAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESVFRGA
GWNVIKLIWDRSWDPLLAQDRDGVLVNKMNMTPDGQFQTYATESGAYIRRHFFGDDHRLR
AMVENLSDDQILHLGRGGHDHRKIFAAFKAANEHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPISDRELESGLPPYYHPGRNSEEIQYMHDRRKGLGGYVP
TRVVRSKALALPDDKAYATVKKGTGQQSIATTMAFVRLLKDLMRDKEIGRRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPMIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACVAYDPAYAYEIAHIVQDGLRRMYGSSAEHPHGEDVFYYLTVYNEPIQH
PAEPADVDVEGIVKGVHKLSDGPGGAIPAQIMASGVAVPWALDAQRILAEDWNVRASVWS
ATSWNELRREAVACEQHNLLHPEEEQLVPYVTRKLSGAEGPFVAVSDWMRSVPDQIARWV
PGTYQSLGADGFGFADTRGAARRFFHIDAQSIVVAVLTELARAGRVDRSVLKQAIDRYQV
LDVTAAHPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaccccgatcatcattggcggccttccgagtcaggtgcct
gacttcgatcccgaagagacccaggagtggctcgactccctggacgccgtcgtggacgag
cgcggccgggagcgggcgcgctatctcatgctgcggctgatcgagcgagcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacacgatcccgaccaagagc
gagccgttcttcccgggcaacgaggagatcgagcgcaggatcctgaacgcgacgcgctgg
aacgcggccgtgatggtctcgcgcgcccagcgccccggcatcggcgtgggcggccacatc
gccaccttcgcctcctcggcgtccctgtacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggtgaccaggtcttcttccagggccacgcctcccccggcatc
tacgcccgcgcctatctgctggaccggctcaccgagaaccagctggacggcttccgccag
gagaagtcggcgtacccgaacggcctgtccagctacccgcacccgcgctccatgccggac
ttctgggagttcccgacggtctccatgggcctcggcccgctgggcgcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgcggacacctccaagtcgcacgtgtgg
gcgttcctgggcgacggcgagatggacgagcccgaatcgctcggccagctcacgctcgcg
gcccgggagggcctggacaacctgaccttcgtggtcaactgcaacctccagcgcctggac
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcggtcttccggggcgcc
ggctggaatgtgatcaagctgatctgggaccgctcctgggacccgctgctcgcgcaggac
cgggacggcgtcctggtcaacaagatgaacatgacgccggacgggcagttccagacgtac
gccaccgagtcgggcgcctacatccgccggcacttcttcggcgacgaccaccggctgcgc
gcgatggtcgagaacctgagcgacgaccagatcctgcacctgggccgcggcggccacgac
caccgcaagatcttcgcggcgttcaaggcggccaacgagcacaagggccagccgacggtc
atcctggccaagacgatcaagggctggacactgggcccgaacttcgagggccgcaacgcc
acccaccagatgaagaagctgacggtcgacgacctgaagcgcttccgggaccggctgcac
ctgccgatctccgaccgggagctggagtccggcctgccgccgtactaccacccggggcgg
aactcggaggagatccagtacatgcacgaccgccgcaagggcctcggcgggtacgtcccc
acgcgcgtggtgcgctccaaggcactcgcgctgccggacgacaaggcgtacgcgaccgtg
aagaagggcaccggtcagcagtccatcgcgaccacgatggcctttgtgcggctgctcaag
gacctcatgcgggacaaggagatcgggcggcgcttcgtgctgatcgcgccggacgagtac
cgcacgttcggcatggactccttcttcccgagcgcgaagatctacaacccgctcggccag
cagtacgagtcggtggaccgggaactgctcctcgcctacaaggagtcgccgaccggccag
atgctgcacgacggcatctccgaggcgggctgcacggcctcgctgatcgcggcgggttcc
gcgtacgcgacgcacggcgagccgatgatcccggtgtacgtcttctactcgatgttcggg
ttccagcgcaccggcgaccagttctggcagatggccgaccagctggcgcgcggcttcgtc
ctcggggcgacggcgggccgtacgacgctcaccggcgagggtctgcaacacgccgacggg
cactcgcagctgctggcctccacgaacccggcgtgcgtcgcgtacgacccggcgtacgcc
tacgagatcgcgcacatcgtccaggacgggctgcgccgcatgtacggcagctcggcggag
cacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagcccatccagcac
cctgcggagccggccgacgtggacgtcgagggcatcgtcaagggcgtccacaagctctcc
gacggtcccggcggggcgatcccggcgcagatcatggcgtcgggcgtcgccgtgccctgg
gccctcgacgcgcagcggatcctcgcggaggactggaacgtacgggcctcggtgtggtcc
gcgacgtcctggaacgagctgcggcgcgaggcggtggcctgcgagcagcacaacctcctg
cacccggaggaggagcagctcgtgccgtacgtgacgcgcaagctgagcggcgcggagggg
ccgttcgtggcggtgtccgactggatgcggtcggtgccggaccagatcgcgcggtgggtg
cccggcacctaccagtccctgggcgcggacggcttcggcttcgcggacacgcggggggcg
gcgcggcgcttcttccacatcgacgcgcagtcgatcgtggtggcggtgctcacggagctg
gcgcgggcggggcgggtggaccgctcggtgctgaagcaggcgatcgaccggtatcaggtg
ctggacgtgacggcggcgcatccgggggcggcggggggcgacgcgtag
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