Streptomyces sp. S6: EQG64_08720
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Entry
EQG64_08720 CDS
T07981
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stry
Streptomyces sp. S6
Pathway
stry00010
Glycolysis / Gluconeogenesis
stry00020
Citrate cycle (TCA cycle)
stry00620
Pyruvate metabolism
stry00785
Lipoic acid metabolism
stry01100
Metabolic pathways
stry01110
Biosynthesis of secondary metabolites
stry01120
Microbial metabolism in diverse environments
stry01200
Carbon metabolism
stry01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
stry00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
EQG64_08720 (aceE)
00020 Citrate cycle (TCA cycle)
EQG64_08720 (aceE)
00620 Pyruvate metabolism
EQG64_08720 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EQG64_08720 (aceE)
Enzymes [BR:
stry01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EQG64_08720 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QCW77524
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Position
1996692..1999424
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AA seq
910 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGDEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDQGDGGDQIFFQGHASPGIYARAFLLDRLSEAQLDAFRQ
EKSKAPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEAHGIADTSKSHVW
AYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRTGILVNKLNTTPDGQFQTYATETGAYIREHFFGDDPRLR
DMVKDMTDQQILHLGRGGHDHRKVYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVEDLKRFRDRLHIPITDKQLDEGYPPYYHPGRDSEEIQYMHDRRNSLGGYVP
TRVVRAKPLPQPEEKTYAAAKKGSGSQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLSRGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACVSYDPAFGYEIAHIMQDGLRRMYGEANEDVFYYLTVYNEPIQHPAEPE
NVDVEGILKGVYRFKQGEAGEIPAQILASGVAVPWAVEAQKILAEEWNVKADIWSATSWN
ELRREAVEVERYNLLHPEEEQRVPYVTRKLDGAEGPFVAVSDWMRSVPDQIARWVPGTYQ
SLGADGFGFADTRGAARRFFHIDAQSIVLAVLTELAKEGKIDRSALKTALDRYDLLDVAA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttccgagccaggtcccg
gattttgatcccgaggagacccaggaatggctcgactccctcgacgccgccgtcgacgag
cgaggccgtgagcgggcccgctatctgatgctccggctcatcgagcgcgcgcgtgagaag
cgcgtcgccgtgccggagatgcgcagcacggactacgtgaacacgatcgccacgaaggac
gagccgttcttccccggcgacgaggagatcgagcgcaaggtcctcaacgcgacgcgctgg
aacgcggccgtgatggtctcgcgggcgcagcgtcccgggatcggtgtcggcggtcacatc
gccaccttcgcctcctccgcctcgctgtacgacgtgggcttcaaccacttcttccgaggc
aaggaccagggcgacggcggcgaccagatcttcttccaggggcacgcgtccccggggatc
tacgcccgcgcgttcctgctggaccggctgagcgaggcccagctcgacgcgttccgccag
gagaagtcgaaggccccgaacgggctgtccagctacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggcccgctcggcgcgatctaccaggcg
cggatgaaccgctacatggaggcgcacggtatcgccgacacctccaagtcgcacgtctgg
gcgtatctgggcgacggcgagatggacgagcccgagtcgctggggcagctctccatcgcc
gcccgtgagggcctggacaacctgaccttcgtggtcaactgcaacctgcagcggctcgac
ggcccggtgcgcggcaacgggaagatcatccaggagctggagtcgcagttccggggcgcc
ggctggaacgtcatcaagctggtctgggaccgctcctgggacccgctgctggcgcaggac
cgcacgggcatcctggtcaacaagctgaacaccacgccggacggccagttccagacgtac
gccaccgagaccggtgcgtacatccgtgagcacttcttcggtgacgacccgcggctgcgg
gacatggtcaaggacatgaccgaccagcagatcctgcacctggggcgcggcggtcacgac
caccgcaaggtgtacgcggcctacgcggcggccaaggcccacaagggccagccgaccgtg
atcctggcgcagacggtcaagggctggacgctggggccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctcacggtcgaggacctcaagcggttccgggaccggctgcac
atcccgatcaccgacaagcagctggacgagggctacccgccctactaccacccgggccgc
gactcggaggagatccagtacatgcacgaccgccgcaacagtctgggcggctatgtgccg
acccgggtggtgcgtgcgaagcccctgccgcagcccgaggagaagacgtacgcggctgcg
aagaagggttcgggttcgcagtcgatcgccaccaccatggcgttcgtccgcatcctgaag
gacctcatgcgggacaaggagatcggtaagcgtttcgtgctgatcgcccccgacgagtac
cgcacgttcggtatggacgcgttcttcccgagcgcgaagatctacaacccgctgggccag
cagtacgaggcggtcgaccgcgatctgctgctcgcgtacaaggagtccccgaccggtcag
atgctgcacgacggcatctccgaggcgggctgcacggcctcgctgatcgccgccggttcg
gcgtacgcgacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggg
ttccagcgcaccggtgaccagttctggcagatggccgaccagctctcgcgcggtttcgtg
ctgggcgcgaccgccgggcgtacgaccctgaccggtgagggcctccagcacgcggacggc
cactcgcagctgctcgcctcgaccaacccggcctgtgtctcctacgacccggccttcggg
tacgagatcgcgcacatcatgcaggacgggctgcgccggatgtacggcgaggccaacgag
gacgtcttctactacctcaccgtctacaacgagccgatccagcacccggccgagccggag
aacgtggacgtggagggcatcctcaagggtgtctaccggttcaagcagggtgaggcgggc
gagatcccggcgcagatcctcgcgtccggtgtggcggtcccgtgggccgtcgaggcgcag
aagatcctcgccgaggagtggaacgtcaaggcggacatctggtcggccacctcctggaac
gagctgcggcgcgaggccgtggaggtggagcggtacaacctgctccacccggaggaggag
cagcgcgttccgtatgtgacgcgcaagctggacggggccgagggcccgttcgtggcggtc
tcggactggatgcgttcggtgccggaccagatcgcgcgctgggtgccggggacgtaccag
tcgctgggcgccgacggcttcggcttcgcggacacgcggggtgcggcgcgccggttcttc
cacatcgacgcccagtcgatcgtcctcgcggtgctcacggagctggcgaaggagggcaag
atcgaccggtcggccctgaagacggcgctggaccgttacgacctcctggatgtggccgca
gccgatccgggcgcggcgggcggcgacgcgtag
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