Streptomyces tsukubensis: B7R87_07520
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Entry
B7R87_07520 CDS
T07155
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stsu
Streptomyces tsukubensis
Pathway
stsu00010
Glycolysis / Gluconeogenesis
stsu00020
Citrate cycle (TCA cycle)
stsu00620
Pyruvate metabolism
stsu00785
Lipoic acid metabolism
stsu01100
Metabolic pathways
stsu01110
Biosynthesis of secondary metabolites
stsu01120
Microbial metabolism in diverse environments
stsu01200
Carbon metabolism
stsu01210
2-Oxocarboxylic acid metabolism
Module
stsu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
B7R87_07520
00020 Citrate cycle (TCA cycle)
B7R87_07520
00620 Pyruvate metabolism
B7R87_07520
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
B7R87_07520
Enzymes [BR:
stsu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
B7R87_07520
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AZK93743
UniProt:
A0A5H2UFU9
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Position
1997540..2000209
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AA seq
889 aa
AA seq
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MTDPVGKLPSELDQLPDRDAEETAEWAASLDAVAQHAGPHRAAYLMRRTLQHAEKAGVPV
PRLLETDYVNTIPTPAEPAFDGDEAMEARITAWNRWNAAAMVTRGARLGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLTEAHLDNFRQEAGGAG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLHNRSIKDTSNSHVWAFLGDGEM
DEPESTAALALAAREQLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKTL
WGNAWDELFALDTTGALVRRLREVPDAQFQTYATRDIAYIREHFFGAEPALAELAKVLTD
AKIAECFYTSRGGHEARKVYAAYRAALAHKGAPTVILAQTVKGHTLGKGFASKNANHQMK
KLSVDEFKDMRELLGLPIPDSAFADGVVPYGHPGADSPEVRYLQERRAALGGPAPVRRVH
QVVLPEPEERGFKALQKGSGNQEMATTMAFVRLVKDLMRDKETGRRWVPIVPDEARTFGM
ESLFPSAGIYSPLGQTYEPVDRDQLMYYKEATDGQILNEGITEAGSMADFIAAATSYATH
GEPMIPFYIFYSMFGWQRTGDQMWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHLI
ASTNPASLNYDPAFAYEIAVIVKDGLRRMYGPDAEDVFYYLTVYNEPKPQPAMPEGVEEG
ILKGLYRFREGTAARPDSPRLQLLASGTAIHWALEAQRMLADEWGVTADVWSATSWGELR
RDALEADEALLRGEERTPYVRQALAGAPGPVIAVSDWMRQVPDQISQWVEQDWSSLGTDG
FGLSDTREAARRHFGVDAPSITVAALAQLARRGEVPASAVKEARERYGL
NT seq
2670 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccgtaggcaagcttccgagcgagctggaccagctcccggatcgcgatgcc
gaggagaccgccgaatgggcggcatccctcgatgccgtcgcccagcacgccggcccccac
cgcgccgcgtacctgatgcgccgcaccctgcagcacgccgagaaggcgggcgtacccgta
ccccggctgctggagacggactacgtcaacaccatccctacccccgccgagcccgccttc
gacggcgacgaggcgatggaagcccggatcacggcctggaaccgctggaacgcggccgcc
atggtgacccgcggcgcccggctgggcgtcggcggccacatcgcgaccttcgcgtccgcg
gcctggctctacgagaccggcttcaaccacttcttccgcgggaaggagggcgacggcagc
ggcgaccagctctacatccagggccatgcctcgcccggcatatacgcccgtgccttcctc
gacggccgcctcaccgaggcccatctcgacaacttccgccaggaggcgggcggtgccggt
ctgccgtcgtacccgcatccgcgccggctgccctggctgtgggagttcccgacggtctcc
atgggcctgggcccgctctccgcgatctaccaggcgcggttcaaccgctatctccacaac
cggtcgatcaaggacacctccaactcgcacgtctgggccttcctcggcgacggcgagatg
gacgagcccgagtcgaccgcggccctcgccctggcggcccgggagcagctggacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggtccggtccgcgccaacttcaag
atcgtccaggagctggaggcccagttccgcggcgccggctggaacgtcgtgaagacgctc
tggggcaacgcctgggacgagctgttcgccctcgacaccaccggtgcgctggtccgccgg
ctgcgcgaggtgccggacgcccagttccagacgtacgcgacccgtgacatcgcgtacatc
cgcgagcacttcttcggcgccgagcccgccctcgccgagctggcgaaggtcctcacggac
gccaagatcgccgaatgcttctacacctcccgcggcggccacgaggcccgcaaggtgtac
gcggcctaccgcgccgccctcgcccacaagggcgcgccgaccgtgatcctcgcgcagacc
gtgaagggccacaccctcggcaagggctttgcgtcgaagaacgcgaaccaccagatgaag
aagctctcggtcgacgagttcaaggacatgcgggagctgctcgggctgccgatcccggac
agcgcgttcgccgacggcgtggtcccctacggccacccgggcgcggactcccccgaggtc
cgctacctccaggagcggcgcgcggccctcggcggccccgccccggtccgccgggtgcac
caggtggtgctgcccgagccggaggagcgcggtttcaaggccctgcagaagggctccggc
aaccaggagatggccaccaccatggccttcgtccgcctggtgaaggacctgatgcgggac
aaggagaccggccgccgctgggtgccgatcgtccccgacgaggcccgtaccttcggtatg
gagtccctcttcccgtccgcgggcatctactcgccgctcggccagacgtacgagccggtc
gaccgcgaccagctgatgtactacaaggaagccacggacggccagatcctcaacgagggg
atcaccgaggccgggtccatggcggacttcatcgccgccgcgacgtcgtacgcgacgcac
ggcgagccgatgatcccgttctacatcttctactccatgttcggctggcagcgcaccggc
gaccagatgtggcagctggccgaccagctcggcaagggcttcatcgtcggcgccaccgcg
ggccgtacgaccctcaccggtgagggcctccagcacgcggacggccactcgcacctgatc
gcgtccacgaacccggcgtcgctcaactacgacccggcgttcgcgtacgagatcgcggtg
atcgtcaaggacggtctgcgccggatgtacggtccggatgccgaggacgtcttctactac
ctgacggtctacaacgagcccaagccgcagcccgcgatgcccgagggcgtcgaggagggc
atcctcaagggcctgtaccgcttccgcgagggcaccgcggcccgtccggactcgccgcgg
ctccagctgctggcgtccggtacggcgatccactgggcgctggaggcgcagcggatgctc
gccgacgagtggggcgtcacggccgatgtgtggtcggcgacgtcctggggcgagctgcgc
cgggacgccctggaggcggacgaggcgctgctccgcggcgaggagcgcaccccgtacgtc
cgtcaggcgctggccggggcgccgggtccggtcatcgcggtcagcgactggatgcggcag
gtgccggaccagatcagccagtgggtcgagcaggactggtcgtccctcggcaccgacggc
ttcggtctgtcggacacccgtgaggcggcgcgccggcacttcggcgtggacgctccgtcg
atcaccgtggcggcgctggcgcagctcgcgcggcgcggcgaggttccggcctcggcggtg
aaggaagcccgggagcgctacgggctctga
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