KEGG   Salmonella enterica subsp. enterica serovar Typhi Ty2: t0090
Entry
t0090             CDS       T00121                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase type I
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
stt  Salmonella enterica subsp. enterica serovar Typhi Ty2
Pathway
stt00670  One carbon pool by folate
stt00790  Folate biosynthesis
stt01100  Metabolic pathways
stt01240  Biosynthesis of cofactors
stt04981  Folate transport and metabolism
Module
stt_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:stt00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    t0090 (folA)
   00670 One carbon pool by folate
    t0090 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    t0090 (folA)
Enzymes [BR:stt01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     t0090 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AAO67823
UniProt: Q8Z9J9
LinkDB
Position
100644..101123
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNI
IISSQPGTDDRVQWVKSVDEAIAACGDAPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtggatcgcgtcatcggtatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcatggtttaaacgtaacacgttaaataaacctgtc
gtcatgggacgtcacacctgggagtccatcggacgccccttaccgggacgtaaaaatatt
attatcagcagccagccgggcaccgacgatcgcgtgcagtgggtgaagtctgtcgatgag
gcgattgccgcttgcggcgatgcgccggaaattatggtcattggcggcgggcgcgtgtac
gagcagttcctgccaaaggcgcagaagctttatctgacgcatattgatgcggaagtcgaa
ggcgatacccattttccggattatgaaccggatgactgggaatcggtattcagtgagttt
cacgatgccgacgcgcagaattctcacagctattgtttcgagattctggagcgtcgttaa

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