Streptomyces tubercidicus: STRTU_002231
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Entry
STRTU_002231 CDS
T09099
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
stud
Streptomyces tubercidicus
Pathway
stud00020
Citrate cycle (TCA cycle)
stud00630
Glyoxylate and dicarboxylate metabolism
stud00785
Lipoic acid metabolism
stud01100
Metabolic pathways
stud01110
Biosynthesis of secondary metabolites
stud01120
Microbial metabolism in diverse environments
stud01200
Carbon metabolism
stud01210
2-Oxocarboxylic acid metabolism
Module
stud_M00009
Citrate cycle (TCA cycle, Krebs cycle)
stud_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
stud00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
STRTU_002231
00630 Glyoxylate and dicarboxylate metabolism
STRTU_002231
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
STRTU_002231
Enzymes [BR:
stud01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
STRTU_002231
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
STRTU_002231
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
STRTU_002231
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
STRTU_002231
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WAU11950
LinkDB
All DBs
Position
2645461..2649234
Genome browser
AA seq
1257 aa
AA seq
DB search
MSLQSPNSSSISTDQEGQGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGATAPSQPAEGSPAAPAAPAQSSAPAAEPKPASAEPATPAKPAASAPAPAKAAPAKAEP
AKPAAKPAADASLAPVGPEFVTLRGPSAAVAKNMSASLELPTATSVRAVPVKLLFDNRIV
INNHLKRARGGKVSFTHLIGYAMVQALKAMPSMNHSFAEKDGKPTLVKPEHVNLGLAIDL
VKPNGDRQLVVAAIKKAETLTFFEFWQAYEDIVRRARDNKLTMDDFTGVTASLTNPGGIG
TVHSVPRLMPGQSMIMGVGAMDYPAEFQGTSQDALNKLGVSKVMTLTSTYDHRVIQGAAS
GEFLRIMSQLLLGENEFFDDIFKSLRIPYEPVRWLRDIDASHDDDVTKAARVFELIHSYR
VRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSMMKLRDILGVLRD
SYCRTTGIEFMHIQDPKQRKWIQDRVERSHKSPEREEQLRILRRLNSAEAFETFLQTKYV
GQKRFSLEGGESVIPLLDAVIDAAAESRLDEAVIGMAHRGRLNVLANIVGKSYAQIFREF
EGNLDPKSMHGSGDVKYHLGAEGIFTGLDGEQIKVSLTANPSHLEAVDPVVEGVARAKQD
IINKGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAP
ESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRG
HNESDNPGFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTE
VRDATTAPVAPEVPQPKAEFPVYVDTAISQEVVKRIAESQVNIPEGRTVHPRLLPQLQRR
AAQVEDNAIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHAVLVDRQTGDDYTPL
LYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPEALVMWEAQFGDFVNGAQTVVDEFIS
SAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAAPTLPSNYFHLLR
WQVHNPHHKPLVVFTPKSMLRLKAAASRTEEFTSGGFRPVIGDSTVKPEDVRKVIFCSGK
VYYDLEAEREKRGANDTAIVRIERLYPLPGKELQAEIAKFPNAEKYLWTQEEPANQGAWP
FLGLNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQAQLVSEAFDA
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacagctcgagcatctcgaccgaccaagaggggcagggtaag
aaccctgctgccgcgttcggtcccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggcggcgccaccgcgccgagccagccggcggagggctcccccgccgctccggccgccccg
gcgcagtcgtccgcacccgcagccgagccgaagccggcctccgctgagccggccaccccg
gcgaagcccgctgcgagcgctccggcaccggcgaaggccgctccggcgaaggccgagccg
gccaagcccgccgcgaagccggccgccgacgcgagcctggctccggtcggtcccgagttc
gtcaccctgcgcggcccctcggccgcggtggcgaagaacatgagcgcctccctggagctg
ccgacggccacgtccgtccgcgcggtcccggtgaagctgctgttcgacaaccgcatcgtg
atcaacaaccacctcaagcgcgcccgcggtgggaaggtctccttcacccacctcatcggg
tacgcgatggtgcaggccctcaaggccatgccgtcgatgaaccactccttcgcggagaag
gacggcaagccgacgctggtcaagcccgagcacgtcaacctcggtctggccatcgacctg
gtgaagccgaacggtgaccgccagctcgtcgtcgccgccatcaagaaggccgagacgctg
accttcttcgagttctggcaggcctacgaggacatcgtccgccgggcccgcgacaacaag
ctcacgatggacgacttcaccggagtcaccgcgtcgctgacgaacccgggcggcatcggc
accgtgcactcggtgccgcgtctgatgcccggccagtccatgatcatgggcgtcggcgcg
atggactaccccgcggagttccagggcacctcgcaggacgccctgaacaagctgggtgtc
tccaaggtcatgacgctgaccagcacctatgaccaccgggtgatccagggcgccgcctcc
ggcgagttcctgcggatcatgagccagctgctgctcggcgagaacgaattcttcgacgac
atcttcaagtcgctgcggattccgtacgagccggtccgctggctgcgcgacatcgacgcc
tcccacgacgacgatgtcaccaaggccgcccgggtcttcgagctgatccactcctaccgg
gtccgcggccacgtcatggccgacaccgacccgctggagtaccaccagcgcaagcacccc
gacctggacatcaccgagcacgggctcaccctgtgggacctggagcgcgagttcgcggtc
ggcggcttctccggcaagtccatgatgaagctgcgcgacatcctgggcgtgctgcgtgac
tcgtactgccgcaccaccggcatcgagttcatgcacatccaggaccccaagcagcgcaag
tggatccaggaccgggtcgagcgctcgcacaagtcgcccgagcgcgaggagcagctgcgc
atcctgcgccggctgaactccgccgaggcgttcgagacgttcctgcagacgaagtacgtc
ggccagaagcgcttctcgctggagggcggcgagtccgtcatcccgctgctggacgcggtc
atcgacgccgcggccgagtcgcggctggacgaggccgtcatcggtatggcccaccgcggc
cgcctcaacgtcctcgccaacatcgtcggcaagtcgtacgcgcagatcttccgggagttc
gagggcaacctcgacccgaagtcgatgcacggctccggcgatgtgaagtaccacctgggc
gccgagggcatcttcaccggcctggacggcgagcagatcaaggtctcgctgaccgccaac
ccctcccacctggaggccgtggacccggtcgtcgagggtgtcgcgcgcgccaagcaggac
atcatcaacaagggcggcacggacttcacggtcctgccgatccagctgcacggtgacgcg
gcgttcgccggccagggcgtggtcgcggagacgctgaacatgtcccagctgcgcggctac
cgcaccggcggcacggtgcacgtcgtcatcaacaaccaggtcggcttcaccgccgccccg
gagtcgtcgcgttcgtccatgtacgccaccgacgtggcccgcatgatcgaggcgccgatc
ttccacgtcaacggtgacgaccccgaggccgtcgtccgcgtggcccgtctggccttcgag
ttccgccaggcgttcaacaaggacgtggtcatcgacctgatctgctaccgccgccgcggc
cacaacgagtcggacaacccgggcttcacccagccgctgatgtacgacctgatcgacaag
aagcgctcggtgcgcaagctctacaccgagtccctcatcggtcgtggcgacatcactctg
gaagaggccgagcaggcgctgcaggacttccagggccagctggagaaggtcttcaccgag
gtccgcgacgccacgacggccccggtggcccccgaggtgccgcagcccaaggccgagttc
ccggtctacgtggacaccgcgatctcccaggaggtcgtcaagcggatcgccgagtcgcag
gtcaacatccccgagggccgcaccgtccacccgcgtctgctgccccagctgcagcgccgc
gcggcccaggtcgaggacaacgccatcgactggggcatgggcgagaccctcgccatcggc
tcgctgctgatggaggggacccccgtccggctcgccggccaggactcccgccgcggcacc
ttcggccagcgccacgcggtgctggtggaccggcagaccggcgacgactacaccccgctg
ctctacctctccgaggaccaggcccgcttcaacgtctacgactcgctgctcagcgagtac
gcggcgatgggcttcgagtacggctactccctggcccgcccggaggcgctggtcatgtgg
gaggcgcagttcggtgacttcgtcaacggcgcccagaccgtcgtcgacgagttcatctcc
tcggcggagcagaagtggggccagacgtccggcgtcaccctgctgctgccgcacggctac
gagggccagggcccggaccactcctcggcccggatcgagcgcttcctccagctgtgcgcg
cagaacaacatgacggtcgcggcgccgaccctgccgtcgaactacttccacctgctgcgc
tggcaggtccacaacccgcaccacaagccgctggtcgtcttcaccccgaagtcgatgctg
cgtctgaaggccgcggcgtcgcggacggaagagttcacgtcgggcggcttccgcccggtc
atcggggactccacggtcaagcccgaggatgtccgcaaggtcatcttctgctccggcaag
gtctactacgacctggaggcggagcgggagaagcgcggcgcgaacgacaccgcgatcgtc
cgtatcgagcgtctctacccgcttcccggcaaggagctccaggcggagatcgccaagttc
ccgaacgccgagaagtacctgtggacccaggaagagccggcgaaccagggtgcctggccg
ttcctcggcctcaacctgatcgaccacctcgacctggccgtcggcgccgatgtcccgcac
ggcgagcggctgcgccggatctcccggccgcactcctcgtcgccggccgtcggctccgcc
aagcgccaccaggcggagcaggcacagctggtctcggaggccttcgacgcctga
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