Streptomyces tuirus: GCM10017668_48040
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Entry
GCM10017668_48040 CDS
T07360
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
stui
Streptomyces tuirus
Pathway
stui00020
Citrate cycle (TCA cycle)
stui00630
Glyoxylate and dicarboxylate metabolism
stui00785
Lipoic acid metabolism
stui01100
Metabolic pathways
stui01110
Biosynthesis of secondary metabolites
stui01120
Microbial metabolism in diverse environments
stui01200
Carbon metabolism
stui01210
2-Oxocarboxylic acid metabolism
Module
stui_M00009
Citrate cycle (TCA cycle, Krebs cycle)
stui_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
stui00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
GCM10017668_48040 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
GCM10017668_48040 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
GCM10017668_48040 (kgd)
Enzymes [BR:
stui01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
GCM10017668_48040 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
GCM10017668_48040 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
GCM10017668_48040 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
GCM10017668_48040 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BCL22961
UniProt:
A0A7G1NJS4
LinkDB
All DBs
Position
complement(5133266..5137081)
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AA seq
1271 aa
AA seq
DB search
MSPQSPSNSSISTDTDQAGKNPAASFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAASTPAGTAAAGAAGTTTAQAAAPAAPAQAPAPAAEKPAAAPAPAPAPAQAKPAAQA
PAQAPAPAQAAPAAKPAAAKKAEPAGEAPSGPEQVVLRGPAAAVAKNMNASLEVPTATSV
RAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKDGKPTL
VKPEHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLGMDDF
TGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTL
TSTYDHRVIQGAASGEFLRIVANLLLGENGFYDDIFEALRIPYEPVRWLKDIDASHDDDV
TKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGGFAGK
SMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHTKPEREEQLRILRRLN
AAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLA
NIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIAVSLVANPSHLEA
VDPVLEGVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTV
HIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFN
KDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQA
LQDYQGQLEKVFTEVREATSQPATVESTDPQAEFPVAVNTAVTTEVVKRIAESQVNIPDH
ITVHPRLLPQLQRRASMVEDGTIDWGMGETLAIGSLLLEGVPVRLAGQDSQRGTFGQRHA
VIIDRTTGDEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPEALVMWEAQFGD
FVNGAQTVVDEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQMCAQNNMTV
AMPTSPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAAAKAEEFTTGQFQPVIGDSSV
DPAAVKKVVFCAGKVYYDLEAERQKRGVTDTAIIRIERLYPLPGTELQAEIKKYPNAEKY
LWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAE
QEQLVREVFEA
NT seq
3816 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcggggaag
aaccctgccgcgtcgttcggtgccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagcca
ggggcggccgccgcctcgactccggcgggtaccgcggccgcgggggccgcggggaccacc
accgctcaggcggccgctccggccgctcccgcccaggcccccgcccccgcggccgagaag
cccgccgccgcgccggctcccgccccggctccggcccaggcgaagcccgccgcgcaggcc
ccggcccaggcacccgctccggcgcaggccgccccggccgccaagccggccgccgcgaag
aaggccgagcccgccggtgaggccccctcgggccccgagcaggtcgtgctgcgcggcccc
gccgccgccgtcgcgaagaacatgaacgcctccctggaggtgcccacggccacgtccgtg
cgcgccgtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctgaag
cgcgcccggggcgggaagatctccttcacgcacctgatcggctacgcgatggtgcaggcc
atcaaggccatgccgtcgatgaactactccttcgcggagaaggacggcaagccgaccctg
gtcaagccggagcacgtcaacttcggcctcgcgatcgacctggtcaagcccaacggcgac
cgccagctcgtggtcgcgggcatcaagaaggccgagacgctgaacttcttcgagttctgg
caggcctacgaggacatcgtccgccgcgcccgcgacggcaagctgggcatggacgacttc
accggcgtgacggtctccctgaccaaccccggcggcctcggcaccgtccactccgtgccg
cgtctgatgcccggccagtcggtgatcatgggcgtcggctccatggactacccggccgag
ttccagggcacgtcccaggacacgctgaacaagctcggcatctcgaaggtcatgacgctc
acgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcggatc
gtcgcgaacctcctcctcggtgagaacggcttctacgacgacatcttcgaggcgctgcgc
atcccctacgagccggtccgctggctcaaggacatcgacgccagccacgacgacgacgtc
acgaaggccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatg
gccgacaccgacccgctggagtaccagcagcgcaagcaccccgacctggacatcaccgag
cacggcctcacgctctgggacctggagcgcgagttcgccgtcggcggcttcgccggcaag
tcgatgatgaagctgcgcgacatcctcggcgtcctgcgcgactcgtactgccgcaccacc
ggcattgagttcatgcacatccaggacccgaagcagcgcaagtggatccaggaccgcgtg
gagcgcccgcacaccaagccggagcgcgaggagcagctgcgcatcctgcgccggctgaac
gcggcggaggccttcgagaccttcctgcagacgaagtacgtcggccagaagcgcttctcg
ctggagggcggcgagtccgtcatcccgctgctggacgcggtgctggactcggccgccgag
tcccgcctggacgaggtcgtcatcggcatggcccaccgcggccgcctgaacgtcctcgcc
aacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccg
aagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcacc
ggcctcgacggcgagcagatcgcggtctccctggtcgcgaacccctcgcacctggaggcg
gtggacccggtcctggagggcgtcgcgcgcgccaagcaggacatcatcaacaagggcggc
acggacttcaccgtcctgccggtggcgatccacggcgacgcggccttcgcgggccagggc
gtggtggccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtc
cacatcgtcatcaacaaccaggtcggcttcaccgcggcccccgagtcctcgcgttcctcc
atgtacgcgacggacgtggcccgcatgatcgaggcaccgatcttccacgtgaacggcgac
gacccggaggccgtggtccgtgtggcccgtctggccttcgagttccgccaggcgttcaac
aaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaac
ccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaag
ctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggccgagcaggcg
ctccaggactaccagggccagctggagaaggtcttcacggaggtccgtgaggccacgtcc
cagccggccacggtcgagtccacggacccgcaggccgagttcccggtcgccgtgaacacc
gcggtgaccacggaggtcgtcaagcggatcgccgagtcccaggtcaacatccccgaccac
atcaccgtccacccgcgtctgctgccgcagctgcagcgccgggcgtcgatggtcgaggac
ggcacgatcgactggggcatgggcgagaccctcgcgatcggctccctcctgctggagggc
gtcccggtccgcctggccggccaggactcgcagcgcggtacgttcggccagcgccacgcg
gtcatcatcgaccgcaccacgggcgacgagtacacgccgctgcagtacctctccgaggac
caggcgcggctcaacgtctacaactccctcctctccgagtacgcggcgatgggcttcgag
tacggctactcgctggcccgccccgaggcgctcgtgatgtgggaggcgcagttcggcgac
ttcgtcaacggtgcgcagacggtcgtggacgagttcatctcgtcggccgagcagaagtgg
gcgcagacctccggtgtcgtcctgctcctgccgcacggctacgagggccagggcccggac
cactcctcggcccgcccggagcgcttcctccagatgtgcgcccagaacaacatgacggtc
gccatgccgacgtcgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccg
caccacaagccgctggtggtcttcacgccgaagtcgatgctgcgcctgaaggcggcggcg
gcgaaggcggaggagttcacgaccgggcagttccagccggtcatcggcgactcctcggtc
gacccggccgcggtcaagaaggtcgtcttctgcgccggcaaggtctactacgacctcgag
gccgagcgtcagaagcgcggcgtgacggacacggcgatcatccgcatcgagcgcctgtac
ccgctgccgggtaccgagctccaggcggagatcaagaagtacccgaacgccgagaagtac
ctgtgggcccaggaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctg
atcgatcacctggacctcgcggtcggcgcggacgtcccgcacggcgagcggctgcggcgc
atctcccgcccgcacggctcgtccccggcggtgggttccgcgaagcggcaccaggcggag
caggaacagctggtgcgtgaggtgttcgaggcgtag
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